Patho Exam 1
• Key Terms (all)
• Pathophysiology Terms Concept Map
• Understanding Pathophysiology
• Modifiable vs Nonmodifiable Risk Factors
• Clinical Manifestations
o signs vs symptoms
o precipitating factors
o remissions vs exacerbations
o subacute
o asymptomatic
o acute vs chronic vs insidious
o local vs systemic
• Diagnosis and Treatment
o Diagnosis
o Prognosis
o Mortality vs Morbidity
• Health vs Illness
• Individual Health
• Population Health
o incidence vs prevalence
o endemic, epidemic, pandemic
• Disease Prevention (including examples of each)
o Primary Prevention
o Secondary Prevention
o Tertiary Prevention
• Evidence-Based Practice
2
Chapter 2 (12-20 questions)
• Key Terms on Quizlet
• Plasma Membrane
• DNA, RNA, and genes
• Cellular Mechanisms of Transportation
o Passive Transport: diffusion, osmosis, & facilitated diffusion
o Active Transport
o Figure 2.3 Mechanisms of cellular membrane transport (p. 13)
o Cellular Function
• Cellular Adaptation & Response to Stress
o Atrophy
o Hypertrophy
o Hyperplasia
o Metaplasia
o Dysplasia
o Ischemia
o Figure 2.5 Adaptive Cell Changes (p. 16)
o Figure 2.6 Breast tissue adaptation to trophic signals (p. 17)
• Cellular Injury & Death
o Apoptosis
o Necrosis
o Causes of cell injury and death pp. 20-21
o Figure 2.10 Cellular Response to Stress (p. 20)
o Figure 2.11 Cellular Response to Oxidative Stress (p. 20)
• Clinical Models (Patho, Clinical Manifestations, Diagnosis & Treatment)
o Cerebral Atrophy
o Cardiac Hypertrophy
o Acromegaly
o Cervical Metaplasia & Dysplasia
o Environmental Toxin Injury and Cardiovascular Disease
3
Chapter 3 (12-20 questions)
• Key Terms on Quizlet
• Lines of Defense
o First Line of Defense
o Second Line of Defense
o Third Line of Defense
o Figure 3.1 (p. 37)
• Manifestations of Inflammation (acute vs chronic; & local vs systemic)
• Acute Inflammation
o Figure 3.3 Tissue In jury Concept Map (p. 39)
o Initial steps in the inflammatory response (p. 41)
o Table 3.3 Local Manifestations of Acute Inflammation (p. 42)
o Table 3.4 Common Blood Tests Used to Detect Acute Inflammation
(p. 43)
o Table 3.5 Common Pharmacologic Agents Used to Treat
Inflammation (p. 43)
• Healing and Tissue Repair
o Figure 3.5 Phases of healing and tissue repair concept map (p. 44)
o Sealing the Wound
o Clearing the Debris
o Restoring Structural Integrity
o Restoring Functional Integrity
• Healing by Intention
o Healing by Primary Intention
o Healing by Secondary Intention
• Complications of Healing and Tissue Repair
o Infection
o Ulcers
o Dehiscence
o Keloids
o Adhesions
• Chronic Inflammation
o Table 3.6 Comparison of Acute and Chronic Inflammation (p. 51)
• Clinical Models (Patho, Clinical Manifestations, Diagnosis, & Treatment)
o Sinusitis (acute and chronic)
o Skin and Burn Injuries
o Burns
o Rheumatoid Arthritis
4
o Gastritis (acute and chronic)
o Pancreatitis (acute and chronic)
o Inflammatory Bowel Disease
o Crohn Disease
o Ulcerative Colitis
Chapter 4 : Altered Immunity (12-20 questions)
• Key Terms on Quizlet
• Review of immune function
• Three lines of defense – first, second, and third
• B cells vs. T-cells
• Table 4.1 Function of Immune Defense Components (focus on B
lymphocytes & T lymphocytes) p. 76
• Figure 4.1 Cellular components involved in immune defense concept map p.
77
• Table 4.2 Primary Rôle of Immunoglobulin Classes p. 78
• Natural killer cells
• Lymphatics
• Innate vs Adaptive Immunity
• Active vs Passive Immunity
• Altered immune function
• Hypersensitivity and hypersensitivity Reactions
• Autoimmunity vs alloimmunity
• Vaccines
• Clinical Models (patho, clinical manifestations, Diagnosis, Treatment)
o HIV/AIDS
o Anaphylactic Reaction
o Systemic Lupus Erythematosus (SLE)
o Table 4.5 Treatment Options for SLE p. 100
o Rh Factor