Midterm Study Guide

Hemodynamic Monitoring & Support Devices

📍 Arterial Lines

  • Leveling: Transducer at 4th ICS, mid-axillary line (phlebostatic axis = right atrium = best place to get a reading and zero out device)

    • Radial is easiest access point for transducer

  • Purpose: Continuous BP monitoring, frequent ABGs

  • Complications: Infection, bleeding, thrombosis, neurovascular injury

📊 Square Wave Test

Assesses the accuracy and functionality of an arterial blood pressure monitoring system. Checks if fluid is properly transmitted to transducer.

Finding

What It Means

Action

Normal: Square + 1–2 oscillations + dicrotic notch

Accurate reading

No intervention

Overdamped

Falsely low BP, no notch

Check for air, clots, kinks, loose connections

Underdamped

Falsely high BP, extra oscillations

Shorten tubing, stabilize patient

Steps: Rapid flush (creates square) → observe waveform → interpret

💧 Central Venous Pressure (CVP)

  • Normal: 2–8 mmHg

  • High (>13–15): Hypervolemia / RV failure → Diuretics (Lasix)

  • Low (<2): Hypovolemia → Fluids

LVAD (Left Ventricular Assist Device)

  • Purpose: Pumps blood from LA → aorta (supports LV)

  • Safety: If battery dies → patient dies

  • Patient Teaching:

    • Carry spare batteries + charger at all times

    • Know how/when to change batteries (before alarm)

    • Avoid water immersion

    • Have emergency contact info ready

CAD, Angina, ACS, & MI

🚨 Not All Chest Pain = MI

  • May see cold, clammy, ashen/gray skin from vasoconstriction

  • Other causes: angina, anxiety, GI, pulmonary

  • Always: ECG + troponins + full assessment

💢 Angina Quick Table

Type

Description

Relief

Troponins

Stable

Predictable, exertional

Rest + sublingual nitro

Normal

Unstable

New/worse, >10 min, unrelieved by rest

Medical emergency (can lead to MI)

Normal

Silent

Ischemia w/o symptoms (common in DM)

N/A

Normal

Key: Angina = no cardiac cell death → no troponin rise

📊 STEMI vs NSTEMI

Feature

STEMI

NSTEMI

ECG

ST elevation

No ST elevation

Troponins

Occlusion

Complete blockage

Partial blockage

Urgency

Emergent: PCI <90 min / thrombolytic <30 min

Urgent cath 12–72 hr

Thrombolytics

🧪 Troponins

  • Draw ASAP in suspected MI

  • ↑ = STEMI or NSTEMI

  • Normal = angina

💊 Nitrates

Action:

  • Vasodilate → ↑ coronary blood flow, ↓ afterload, ↓ O₂ demand

Side Effects (too much): Hypotension, headache

Education:

  1. Sit/lie down before taking

  2. 1 dose → wait 5 min

  3. No relief after 3 doses (15 min) → call 911

  4. Keep in dark glass container/same container, replace q6mo

  5. No PDE-5 inhibitors (Viagra, Cialis)

🩺 Modifiable CAD Risks

  • Hypertension

  • Smoking

  • Hyperlipidemia

  • Obesity

  • Inactivity

  • Diabetes control

Congestive Heart Failure (CHF)

🩺 S/S of CHF

  • Chest pain

  • SOB / orthopnea

  • Dizziness / lightheadedness

  • Swelling (edema)

  • Sudden weight gain

  • Fatigue / weakness

  • Assessment Findings:

    • Crackles in lungs

    • S3 heart sound

    • Tachycardia

    • Hypotension (late, when heart can’t compensate)

    • Hypervolemia

  • Treatment:

    • Diuretics (first check potassium)

Common Reasons for Readmission

  • Noncompliance (not taking meds as prescribed)

  • Wrong meds or incomplete discharge orders

  • Cannot afford meds

📏 Patient Education

  • Daily weights — report >2 lb in 1 day or >5 lb in 1 week

  • Low sodium diet — ≤2 g/day

  • Fluid restriction — ≤2 L/day

🔄 Compensation Mechanisms in CHF

  • SNS activation → ↑ HR, ↑ contractility, vasoconstriction

  • RAAS activation → ↑ sodium & water retention → ↑ preload

  • Ventricular remodeling → dilation & hypertrophy (long-term damage)

💊 Medications for HF Patients

Med

Class/Action

Effect

Side Effects

Inotropes (dobutamine, milrinone, isoproterenol)

↑ contractility

↑ CO

Dobutamine → HTN; milrinone → hypotension

Nitroprusside

Vasodilator

↓ afterload

Cyanide toxicity

Carvedilol

Beta-blocker

↓ SNS, ↓ afterload

Can mask hypoglycemia, bradycardia

Torsemide

Loop diuretic

↓ preload (fluid offload)

Hypokalemia

Eplerenone

Aldosterone antagonist

↓ preload

Hyperkalemia

Dysrhythmias & Lethal Rhythms

💀 Lethal Rhythms

Rhythm

Key Features

Shockable?

First Steps & Treatment

Ventricular Tachycardia (VT)

Wide QRS, no P wave, fast rate

Check pulse first

With pulse & stable = IV amiodarone.

With pulse & unstable = IV amiodarone + synchronized cardioversion;

Without pulse = CPR + defibrillation

Ventricular Fibrillation (VF)

Chaotic, irregular QRS, no CO

Defib VFib → CPR immediately

Asystole

Flat-line, no ventricular activity

CPR + ACLS (epi), Do NOT shock

2nd Degree AV Block Type II

PR normal & consistent, randomly drops QRS

(pacing, not shock)

Can deteriorate to asystole → pacemaker

3rd Degree AV Block

P waves & QRS independent, regular P-P & R-R

(pacing, not shock)

Pacemaker; dopamine/epi as bridge

📌 Other Key Dysrhythmias

Rhythm

Key Features

Treatment

SVT

Narrow complex tachycardia

Vagal maneuver → adenosine → cardioversion if SBP >90

Atrial Fibrillation

Irregularly irregular, no P waves

Rate control (β-blocker, CCB), amiodarone, anticoagulation

Unstable Tachycardia

Any rapid rhythm causing instability

Immediate cardioversion

1st Degree AV Block

PR >0.20 sec, consistent

Monitor, not lethal

2nd Degree AV Block Type I (Wenckebach)

PR gets longer, drops QRS

Usually benign, monitor

Synchronized Cardioversion vs. Defibrillation

Method

Use For

Synchronized Cardioversion

Unstable VT (with pulse), SVT,  A-Fib

Defibrillation

VFib, pulseless VT

If PT has pauses in the heart on monitor -> anticipate pacemaker. 

AAA, TAA, & Dissection

🔍 Key Definitions

  • AAA (Abdominal Aortic Aneurysm)Bulge in abdominal aorta

  • TAA (Thoracic Aortic Aneurysm) – Bulge in thoracic aorta

  • Dissection – Tear in aortic intima → blood enters media → separation of layers

🕒 Assessment

  • Any aneurysm: Assess q6–12 hrs for changes

  • Goal: Detect expansion or rupture early

Predisposing Factors

  • Older age

  • Hypertension

  • Atherosclerosis

  • Genetic connective tissue disorders (Marfan, Ehlers-Danlos)

📍 AAA Specifics

  • Clue: No circulation below diaphragm → Blue Toe Syndrome (poor perfusion to legs)

  • Possible abdominal bruit

  • Pulsatile abdominal mass (don’t palpate vigorously!)

📍 TAA Specifics

  • Compresses airway/lungs → cough, dyspnea

  • May cause hoarseness, dysphagia if compressing recurrent laryngeal nerve/esophagus

💥 AAA Rupture

  • Grey Turner’s Sign → flank bruising from retroperitoneal bleed

💢 Dissection

  • Symptoms:

    • Sudden, severe tearing/ripping back pain

    • Hypotension/weakness

    • Muffled heart sounds (possible pericardial tamponade)

  • Intervention: Emergency surgery ASAP

🫀 Treatment for Any Aneurysm

  • Control BP & HR to reduce aortic wall stress

    • β-blockers, vasodilators as ordered

  • Surgery if:

    • Symptomatic

    • Rapidly expanding

ABGs, ARDS, ARF, Respiratory Failure

📊 ABG Basics

Value

Normal Range

pH

7.35 – 7.45

PaCO₂

35 – 45 mmHg

HCO₃⁻

22 – 26 mEq/L

PaO₂

80 – 100 mmHg

🧮 Interpreting ABGs

  1. Look at pH – Acidotic (<7.35) or alkalotic (>7.45)?

  2. Look at PaCO₂ – If abnormal in opposite direction of pH → respiratory cause.

  3. Look at HCO₃⁻ – If abnormal in same direction as pH → metabolic cause.

  4. Compensation:

    • Uncompensated – opposite value normal

    • Partially compensated – opposite value abnormal but pH still abnormal

    • Fully compensated – opposite value abnormal but pH normal

📍 Acid-Base Types

Condition

pH

PaCO₂

HCO₃⁻

Respiratory Acidosis

Normal or ↑ (comp)

Respiratory Alkalosis

Normal or ↓ (comp)

Metabolic Acidosis

Normal or ↓ (comp)

Metabolic Alkalosis

Normal or ↑ (comp)

🫁 Respiratory Failure

  • PaO₂ <60 mmHg (hypoxemia) and/or PaCO₂ >45 mmHg (hypercapnia)

  • Types:

    • Hypoxemic → Low O₂, normal/low CO₂ (O₂ problem)

    • Hypercapnic → High CO₂ (ventilation problem)

🔴 Hypercapnic Respiratory Failure

  • Cause: Hypoventilation, airway obstruction, neuromuscular weakness

  • On vent:Peak Inspiratory Pressure (PIP) = bad (obstruction, bronchospasm, kinked tube, mucus plug)

  • Fix: Suction, check tubing, bronchodilators

💥 ARDS (Acute Respiratory Distress Syndrome)

  • Cause: Inflammatory injury to alveoli → ↑ permeability → pulmonary edema

  • Criteria:

    • Acute onset

    • Refractory hypoxemia

    • PaO₂/FiO₂ ratio ≤300

  • Treatment:

    • Low tidal volume ventilation

    • ↑ PEEP

    • Prone positioning

    • Treat cause

Airway & Ventilator Management

🛡 VAP (Ventilator-Associated Pneumonia) Bundle

  • HOB ≥30° (prevent aspiration)

  • Oral hygiene (chlorhexidine rinse per protocol)

  • Suction as needed (keep airway clear, prevent micro-aspiration)

  • Daily sedation vacation & readiness-to-wean assessment (if protocol)

💢 If Pt is “Fighting the Vent”

  • If necessary → Paralytic (neuromuscular blocker) per order to improve synchrony with ventilator

  • Always pair paralytics with sedation & analgesia

🚨 Sudden Respiratory Distress on Vent

Steps:

  1. Remove from ventilator

  2. Manually ventilate with Ambu bag + 100% O₂

  3. Call for help 

Bad Respiratory Pattern: 

  • Apneustic (spaced mountains) -> caused by brain stem injury/lesion or CVA

Acute Intracranial Problems

🧮 Key Formulas

  • CPP (Cerebral Perfusion Pressure) = MAP − ICP

    • Normal CPP: 60–100 mmHg

    • <50 mmHg: Ischemia risk

    • <30 mmHg: Incompatible with life

  • MAP (Mean Arterial Pressure) = (SBP + 2 × DBP) ÷ 3

Signs of Increased ICP

  • Halo Sign: Clear/yellow CSF ring around blood on dressing

  • Battle Sign: Bruising over mastoid (possible basilar skull fracture).

  • Cushing’s Triad:

    • Widened pulse pressure

    • Bradycardia

    • Irregular respirations

📊 Glasgow Coma Scale (GCS)

  • Mild: 13–15

  • Moderate: 9–12

  • Severe: <8 → consider intubation

💥 Management of High ICP

  • Surgical: Craniotomy if indicated

  • Medical: Mannitol (osmotic diuretic) to pull fluid from brain

  • Positioning: HOB 30°, neck neutral/midline

  • Environment: Calm, minimal stimulation

  • Avoid: Coughing, straining, Valsalva

  • Temp control: Prevent fever (↑ metabolic demand)

  • Ventilation: Keep CO₂ in normal range (hypercapnia → vasodilation → ↑ ICP)

Spinal Cord Injuries (SCI)

1. Causes of Spinal Cord Injuries

  • Violence (e.g., gunshots, stab wounds)

  • Sports injuries (contact sports, tackles)

  • Diving accidents (hitting head on shallow water)

  • Falls (especially in elderly or high falls)

2. Types of SCI Injury

  • Primary Injury:

    • Direct trauma to spinal cord

      • Penetrating (stab, bullet) or blunt trauma (impact, compression)

    • Immediate damage

  • Secondary Injury:

    • Progressive damage after primary injury

      • Inflammation, ischemia, edema cause further permanent damage

    • Monitor carefully for worsening neuro status

3. Most Unstable Injury

  • Flexion-Rotation injury = Most unstable spinal injury

4. Respiratory Concerns in SCI

  • Cervical injuries (C1–C8) especially risky for breathing

  • Higher cervical lesions → respiratory muscle paralysis (diaphragm, intercostals)

5. Autonomic Dysreflexia (AD)

  • Occurs in SCIs above T6 and can lead to a life-threatening hypertensive crisis if not managed properly.

  • Avoid: Full bladder, bowel impaction, tight clothing, SCDs, pain stimuli

  • Symptoms:

    • Sudden hypertension (↑BP)

    • Flushing above injury level (facial)

    • Bradycardia (slow HR)

    • Headache, sweating

  • Emergency!

    • Sit patient up

    • Remove triggering factors immediately

    • Catheterize bladder if needed

    • Notify provider promptly

6. Cauda Equina Syndrome (CES)

  • Injury below L1–L2 (nerve roots, not spinal cord itself)

  • Symptoms:

    • Complete sensory loss in saddle area (between legs, buttocks, inner thighs, back of legs)

    • Asymmetric lower extremity weakness & pain

    • Bowel/bladder dysfunction (urgent!)

  • Needs urgent surgical decompression

7. Guillain-Barré Syndrome (GBS)

  • Autoimmune ascending paralysis (starts in legs → moves up)

  • Severe respiratory muscle weakness → monitor closely

  • Treatment: IV Immunoglobulins (IVIG) or plasmapheresis

Cranial Nerves

CN # & Name

Type

Main Function

I – Olfactory

Sensory

Smell

II – Optic

Sensory

Vision

III – Oculomotor

Motor

Eye movement (up, down, medial), eyelid opening, pupil constriction

IV – Trochlear

Motor

Eye movement (down & inward)

V – Trigeminal

Both

Facial sensation, corneal reflex, chewing

VI – Abducens

Motor

Lateral eye movement

VII – Facial

Both

Facial expressions, taste (anterior 2/3 tongue), eyelid closing, saliva/tear production

VIII – Vestibulocochlear

Sensory

Hearing & balance

IX – Glossopharyngeal

Both

Taste (posterior 1/3 tongue), gag reflex, swallowing

X – Vagus

Both

Parasympathetic control of heart, lungs, digestion; gag reflex

XI – Accessory

Motor

Shoulder shrug & head rotation

XII – Hypoglossal

Motor

Tongue movement

Assessments:

  • CN I Olfactory (Smell)

    • Assessment: Close 1 nostril and identify familiar scents.

  • CN II Optic (Vision)

    • Assessment:

      • Visual Field: Ask pt to look at bridge of your nose and indicate when object from periphery is seen (peripheral vision).

      • Visual Acuity: Ask pt to read Snellen chart.

  • CN III (Oculomotor), CN IV (Trochlear), CN VI (Abducens)

    • Assessment: Ask pt to hold head steady and assess extraocular muscles by moving finger in 6 directions and PERRLA (Pupils Equal, Round, Reactive to Light & Accommodation)

  • CN V Trigeminal (facial sensation/corneal reflex/chewing)

    • Assessment: Ask pt to close eyes and identify light touch & pinpricks on face, clench teeth and assess strength

  • CN VII Facial (Facial expression/taste anterior 2/3 tongue)

    • Assessment: Ask pt to raise eyebrows, close eyes tightly, purse lips, smile & frown. Taste test (sweet/salty).

  • CN VIII Vestibulocochlear (hearing/balance) → Sensory

    • Assessment:

      • Hearing: Ask pt to close eyes and indicate when he/she hears rustling of fingertips.

  • CN IX Glossopharyngeal (swallowing/gag reflex/taste posterior ½ tongue) and CN X Vagus (Parasympathetic to heart, lungs, digestive system, gag reflex)

    • Assessment: Gag reflex

  • CN XI Accessory (Sternocleidomastoid/neck and trapezius muscle movement) → Motor

    • Assessment: Shoulder shrug and turns head side-to-side against resistance.

  • CN XII Hypoglossal (Tongue movement) → Motor

    • Assessment: “Stick out your tongue” and push tongue side-to-side against resistance from a tongue blade.

Stroke 

Topic

Key Points

Ischemic Stroke

Clot → ischemia → thrombectomy + thrombolytics if within window

Hemorrhagic Stroke

Bleeding → avoid worsening bleed → stop bleed (causes: trauma)

Right-sided stroke signs

Impulsive, left neglect, memory, safety risks

*Left-sided stroke signs

Slow, cautious, speech difficulties (expressive aphasia)

*Aneurysm rupture

Worst headache + N/V → emergency

*Aphasia

Language impairment → use simple, supportive communication (gestures, yes/no, picture boards)


Expressive aphasia: Difficulty producing speech

Receptive aphasia: Difficulty understanding speech