2A-2B

Question

Answer

What elements belong to Group IIA?

Beryllium (Be), Magnesium (Mg), Calcium (Ca), Strontium (Sr), Barium (Ba), Radium (Ra)

What is the mnemonic for Group IIA elements?

Be My Cute Sweet Baby Rat

What are the general properties of Group IIA metals?

Harder, less reactive than Group IA; activity increases down the group; form M2+ ions; basic oxides and hydroxides.

Is beryllium used in medicine?

No, it’s the most toxic alkaline earth metal.

What is beryllium used for?

Fluorescent lamps.

What type of cation is magnesium in the body?

2nd most abundant intracellular cation.

What compound in plants contains magnesium?

Chlorophyll.

What reagent contains magnesium in organic chemistry?

Grignard reagent (RMgX).

What are magnesium’s pharmacologic actions?

Laxative, depressant, natural Ca-channel blocker.

What is the antidote for magnesium toxicity?

Calcium gluconate.

List important magnesium compounds and their uses.

MgCO3 – Antacid/laxative; MgO – Universal antidote; MgSO4 – Epsom salt; Mg(OH)2 – Milk of Magnesia; Talc – Dusting powder; Mg citrate – Cathartic.

What type of cation is calcium in the body?

2nd most abundant extracellular cation.

What is the major calcium compound in bones and teeth?

Hydroxyapatite.

Which vitamin is required for calcium absorption?

Vitamin D.

What are calcium’s pharmacologic roles?

Blood coagulation, muscle contraction, neurotransmitter release.

Name common calcium deficiency diseases.

Osteoporosis, Osteomalacia, Rickets, Hypocalcemia.

List important calcium compounds and their uses.

CaCO3 – Antacid; CaCl2 – Electrolyte; Ca gluconate – Mg antidote; Ca lactate – Supplement; Ca(OH)2 – Antacid/saponifier; CaO – Quicklime; Ca3(PO4)2 – Bone ash; Ca(OCl)2 – Disinfectant; CaSO4 – Plaster of Paris.

What is strontium used for?

Red fireworks, bone scan tracer.

What compound in Sensodyne acts as desensitizer?

Strontium chloride (SrCl2).

What is barium toxicity called?

Baritosis.

What is the antidote for barium poisoning?

Epsom salt (MgSO4).

What color does barium produce in fireworks?

Green.

What is barium sulfate used for?

Radiopaque agent for GIT imaging.

Who discovered radium?

Curie.

What is the first radioactive element discovered?

Polonium.

What are radium’s medical uses?

Radiotherapy, diagnostic imaging.

Which elements belong to Group IIB?

Zinc (Zn), Cadmium (Cd), Mercury (Hg).

What is the mnemonic for Group IIB?

Zinc Can Melt.

What are general properties of Group IIB metals?

Exhibit auto-complexation; only zinc is amphoteric.

Where is zinc found biologically?

Insulin, carbonic anhydrase.

What is zinc used for industrially?

Galvanized iron (iron coating).

What are zinc deficiency and toxicity diseases?

Deficiency – Parakeratosis; Toxicity – Metal Fume Fever.

What is zinc’s main ore?

Sphalerite.

List important zinc compounds and their uses.

ZnCl2 – Disinfectant; ZnO – Protectant; ZnS – White sulfide; ZnSO4 – Emetic; Zn silicate – Protectant; Zn eugenol – Dental cement.

What is the toxic disease caused by cadmium?

Itai-Itai disease.

What are the antidotes for cadmium poisoning?

BAL or EDTA.

What are cadmium’s uses?

Astringent, used in stink bombs.

List important cadmium compounds and their uses.

CdCl2 – Emetic; CdS – Anti-seborrheic; CdSO4 – Ophthalmic antiseptic.

What are other names for mercury?

Quicksilver, Messenger of the gods.

What is the natural source of mercury?

Cinnabar (HgS).

What are mercury-related diseases?

Minamata disease, Acrodynia (Pink disease), Erethism.

What is the antidote for mercury poisoning?

EDTA.

List important mercury compounds and their uses.

Hg2Cl2 – Calomel (cathartic); HgCl2 – Corrosive sublimate; HgI/HgI2 – Syphilis/ulcers; HgO – Yellow precipitate; NH2HgOH – White precipitate (anti-infective).

Most toxic metal?

Beryllium (Be).

Natural Ca-channel blocker?

Magnesium (Mg).

Antidote for Mg toxicity?

Calcium gluconate.

Antidote for Ba poisoning?

Magnesium sulfate (Epsom salt).

Antidotes for Cd and Hg poisoning?

BAL or EDTA.

Disease associated with cadmium?

Itai-Itai disease.

Disease associated with mercury?

Minamata/Pink disease, Erethism.

Disease associated with barium?

Baritosis.

Disease associated with zinc?

Parakeratosis.

Universal Antidote components?

1 part MgO, 2 parts Charcoal, 1 part Tannic Acid.

Sensodyne active ingredient?

Strontium chloride (SrCl2).

Radiopaque compound for imaging?

Barium sulfate (BaSO4).

Bone tracer element?

Strontium (Sr).

Metal used to galvanize iron?

Zinc (Zn).

First radioactive element discovered by Curie?

Polonium.