Human Nutrition (2.13-2.20)
- Diet: The total nutrients that we need for our growth and development
- Balanced Diet: The diet that provides all the required nutrients in appropriate proportions * If the diet does not provide you nutrients we suffer from malnutrition
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- Components of a Balanced Diet:
- Carbohydrates
- Proteins
- Fats
- Vitamins
- Minerals
- Water
- Dietary fibre
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Dietry Needs
- @@Energy requirements vary from one individual to the next@@ depending on age, sex, body composition and physical activity level
- The basal metabolic rate (BMR) is the rate at which a person uses energy to maintain the basic functions of the body * Infants and young children tend to have a proportionately high BMR for their size due to their rapid growth and development. * Men usually have a higher BMR than women since they tend to have more muscle. * Older adults usually have a lower BMR than younger people since their muscle mass tends to decrease with age
- Energy is obtained, from the food and drink we consume by respiration * To lose weight energy expenditure must exceed intake * To gain weight energy intake must exceed expenditure
- Pregnant women need more energy than a non pregnant female likewise lactating mothers also need extra energy for the production of milk * This is due to increased maternal and fetal metabolism for fetal and placental growth during pregnancy
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Components of a balanced diet
- Carbohydrates: Source of energy * Bread, cereal, pasta, rice, potatoes
- Protein: Growth and repair * Meat, fish, eggs, pulses, nuts
- Lipids: Insulation and energy storage * Butter, oil, nuts
- Dietary fibre: Provides bulk for intenstine to push food through * Vegetables, whole grains
- Water: Needed for chemical reactions to take place in cells

- @@Malnutrition is caused by not eating a balanced diet@@ * Obesity: excessive nutrients * Starvation: insufficient nutrients * Coronary heart disease: excessive saturated fat and cholesterol * Kwashiorkor: too much carbohydrates, too little protein * Constipation: lack of fibre
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Alimentary Canal
- Ingestion: Taking in of substances e.g. food and drink into the body through the mouth
- Egestion: Passing out of food (as feces) that has not been digested or absorbed via the anus
- Mechanical digestion: Break down of food into smaller pieces without chemical change to food molecules
- Chemical digestion: Break down of large insoluble molecules into small soluble molecules
- Absorption: Movement of chemically digested food molecules through the small intestine walls into the blood
- Assimilation: Movement of digested food molecules into the cells of the body where they are used and become a part of the cells

- Mouth: Digestion of food starts in the mouth. Teeth break down the food (mechanical digestion) and mix it with the enzymes in saliva (chemical digestion)
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- Oesophagus: This is a thin tube that connects the mouth to the stomach * Bolus are passed down by peristalsis from the mouth to the stomach. * Peristalsis: the contraction and relaxation of the esophagus wall muscles which creates a wave-like motion that pushes the food down the canal.
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- Stomach: This is a muscular bag which mixes food and drink with acid * Mechanical digestion occurs as the stomach walls squeeze the food to liquefy it * Gastric juices contain pepsin (a protease) which chemically digests proteins. It also contains hydrochloric acid which kill bacteria, but also maintains an optimum acidic pH for pepsin
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- Liver: This releases a chemical called bile into the intestines * Bile emulsifies fat into droplets to increase the surface area for lipases to come and digest them (mechanical digestion) * Bile is also basic which assists in neutralizing the acidity of the food coming from the stomach into the intestine
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- Pancreas: Secretes pancreatic juice containing enzymes into the intestines which break down carbohydrates, protein and lipids in food
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- Small intenstine: Carbohydrates, proteins and lipids are digested here and absorbed into the blood
1. Duodenum: The first part of the small intestine. It receives pancreatic juice 2. Ileum: Second part of the small intestine
1. Inner walls have finger like extensions (villi) which increases the surface area for nutrient absorption
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- Large intestine: Undigested food (mainly fibre) passes into the large intestine. Water reabsorbed here
1. Colon: The second part of the large intestine.Reabsorbs water from undigested food and also bile salts to return back to the liver. 2. Rectum: Stores faeces until egestion 3. Anus: Muscles control egestion of feces
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Diarrhoea
Diarrhoea: The loss of watery faeces
- Can cause loss of significant amounts of water and ions causing tissues to stop working properly
- Treated by Oral Rehydration Therapy * Drink with small amount of salt and sugar dissolved
- Caused by infection by vibrio cholerae bacteria
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- The Bacteria releases toxins which causes chloride ions to be secreted into the small intestine. This causes the @@osmotic movement of water into the gut@@, and leads to diarrhea.
- Bacteria attach to the wall of the small intestine
- They produce a toxin
- Due to the toxin chloride ions are released from inside the cells and into the lumen of the intestine.
- The chloride ions accumulate in the lumen of the small intestine and @@lower the water potential@@ there
- When the water potential is lower than the cells lining the intestine, @@water moves out of the cells into the intestine by osmosis.@@
- Large quantities of water are lost from the body in watery faeces
- The blood contains too little chloride ions and water -dehydration

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Mechanical Digestion
- Mechanical digestion: breakdown of food into smaller pieces without chemical change to the food molecules * @@Primarily done through chewing, stomach churning, and the emulsification of fats by bile in the duodenum@@
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- The teeth increase the surface area of food so it can be exposed to saliva for faster digestion * Incisors - chisel-shaped for biting and cutting * Canines - pointed for tearing, holding and biting * Premolars and molars - larger, flat surfaces with ridges at the edges for chewing and grinding up food


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Dental decay
- Dental decay is caused by bacteria which is present on the surface of our teeth.
- The bacteria and food deposits form a layer called plaque.
- Bacteria in plaque feed on sugars which @@produce acid@@ * The acids gradually @@dissolve the enamel coating of the teeth@@, working its way into the dentine * Dentine is softer than enamel and so dissolves more easily and quickly
- As the hole deepens it may eventually reach the nerves which result in pain
\ Dental Care
- Avoid sugary food so that bacteria cannot make acid
- Regular cleaning to remove plaque
- Use floss to remove trapped food
- Visit the dentist regularly for treating early decay and removal of thick plaque
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Chemical Digestion
- Chemical digestion: Breaking down large, insoluble food into smaller soluble nutrients that can be absorbed and used by the cells * Carried out by enzymes

Bile has two main roles:
- It is alkaline to neutralise the hydrochloric acid which comes from the stomach
- The enzymes in the small intestine have a higher (more alkaline) optimum pH than those in the stomach
- It breaks down large drops of fat into smaller ones (emulsification). The larger surface area allows lipase to chemically break down the lipid into glycerol and fatty acids faster
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Absorption
- Absorption: movement of digested food molecules from the digestive system into the blood * Absorption takes place in the second section of the small intestine, the ileum
- Due to its long length, folded surface, and presence of microvilli the ileum is adapted for absorption. * @@These adaptations largely increase the surface area allowing for faster more efficient absorption@@

- Microvilli on the surface of the villus increase surface area for faster absorption of nutrients
- Wall of villus is one cell thick meaning that there is only a short distance for absorption to happen by diffusion and active transport
- Well supplied with a network of blood capillaries that transport glucose and amino acids away from the small intestine in the blood
- Lacteal runs through the centre of the villus to transport fatty acids and glycerol away from the small intestine in the lymph
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