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Chapter 2
Chapter 2
Signals are constantly sent and recieved to maintain homeostasis
Organism → Communication → Cell → Communication → Organism
communication
first and second messengers
hormones
growth factors
cytokines
neurotransmitters
action potenial
cell responses
secretion
contraction
metabolic
Communication modes
probably not all of the modes we have
endocrine
hormones
takes longer
travels in bloodstream
paracrine
different types of cells, but next to each other (diffusion)
controls development and differentiation
growth factors, cytokines, vasoactive agents, neurotransmitters
autocrine
same type of cells next to each other
basically paracrine, but with the same type of cell
juxtacrine
next to each other, giving handshakes
integral membrane proteins
B and T cels
adhesion molecules, membrane-bound cytokines, extracellular matrix
synaptic
specialized paracrine
neurotransmitters
Signal Pleiotropy
one signal has many meanings
different cell types and different receptors/proteins do different things with the same signal
Early and Late Responses
Early (fast): just have to modify a protein (seconds)
Late (slow): requires transcription/translation (min-hour)
Vocab Review
Ligand: binds to a receptor
Agonist: binds to and activates receptor
Antagonist: binds to and inhibits receptor
Receptor: binds ligand and transduces signal
transduction/transduce: to change the form of
Second messanger: ligand produced (cAMP) or relased (Ca2+) into cytosol that carries the signal around the cell
Inverse agonist: binds to receptor and inhibits its intrinsic activity (keeps it inactive)
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Period 8: 1945-1980
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L2 Movement mechanics and Contraction types
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Studied by 37 people
5.0
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Romanticism and Realism (in class 1/25)
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Studied by 1 person
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Chapter 1: Introduction to Forensic Medicine
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Studied by 47 people
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Exam 1 Study Guide // CH 1-3
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Studied by 13 people
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AFPF casus 4
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Studied by 3 people
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