Adult Brain Regions: Understand the different areas of the adult brain, which include:
Cerebrum: Divided into lobes - frontal, parietal, temporal, occipital.
Cerebellum: Coordinates movement and balance.
Diencephalon: Thalamus, hypothalamus, and epithalamus functions.
Brain Stem: Midbrain, pons, and medulla with vital functions.
White and Gray Matter:
Gray Matter: Comprised of neuron cell bodies, unmyelinated axons; involved in processing information, found on the outer layer of the brain.
White Matter: Composed primarily of myelinated axons; responsible for communication between different brain regions.
Ventricles of the Brain:
Four ventricles: Left and right lateral, third, and fourth ventricles.
Function: Produce and circulate cerebrospinal fluid (CSF).
Know the path of CSF circulation:
From lateral ventricles → third ventricle → cerebral aqueduct → fourth ventricle → subarachnoid space.
Cerebral Cortex:
Major functional areas include sensory, motor, and association areas.
Functions of regions:
Frontal Lobe: Decision making, problem-solving, motor function.
Parietal Lobe: Processing sensory information, spatial orientation.
Temporal Lobe: Auditory processing, memory, and language.
Occipital Lobe: Visual processing.
Diencephalon Structures and Functions: Know major features like:
Thalamus: Relay station for sensory information.
Hypothalamus: Regulates homeostasis, temperature, thirst, and sleep.
Epithalamus: Involved in the sleep-wake cycle.
Brain Stem Regions: Understand individual components:
Midbrain: Vision, hearing, motor control.
Pons: Relays messages between cerebellum and cerebrum; regulates breathing.
Medulla Oblongata: Controls autonomic functions such as heart rate and respiration.
Cerebellum: Coordinates voluntary movements, balance, and motor learning.
Limbic System and Reticular Formation:
Limbic System: Key role in emotions and memory.
Reticular Formation: Regulates arousal and consciousness.
Meninges: Three layers with distinct characteristics:
Dura Mater: Outermost, tough layer.
Arachnoid Mater: Middle layer, web-like structure.
Pia Mater: Delicate, innermost layer adhering to the brain's surface.
Cerebrospinal Fluid (CSF):
Functions: Cushions the brain, provides nutrients, removes waste.
Composition includes water, glucose, electrolytes, and proteins.
Homeostatic Imbalances: Familiarize with conditions like:
Hydrocephalus: Accumulation of CSF leading to increased intracranial pressure.
Multiple Sclerosis: Autoimmune disease affecting myelin sheath in CNS.
Spinal Cord Structure and Function:
Comprised of segments: cervical, thoracic, lumbar, sacral regions.
Dorsal Horns: Sensory neuron synapses; receive sensory input.
Ventral Horns: Motor neurons; send output to skeletal muscles.
Flaccid vs. Spastic Paralysis:
Flaccid Paralysis: Result of lower motor neuron injury; leads to muscle atrophy and weakness.
Spastic Paralysis: Result of upper motor neuron damage; characterized by stiff, tight muscles.
Spinal Cord Trauma: Understand terms like paraplegia (loss of function in legs) and quadriplegia (loss of function in all four limbs).
Poliomyelitis and ALS:
Poliomyelitis: Viral infection affecting spinal cord and motor neurons, leading to paralysis.
Amyotrophic Lateral Sclerosis (ALS): Progressive neurodegenerative disease affecting motor neurons, causing muscle weakness and atrophy.
Sensory Receptors Classifications:
By stimulus type (mechanoreceptors, thermoreceptors, photoreceptors, etc.).
By location (exteroceptors for outside stimuli, interoceptors for internal stimuli).
Unencapsulated vs. Encapsulated Receptors:
Unencapsulated: Free nerve endings; example includes nociceptors (pain).
Encapsulated: Specialized structures; example includes Meissner's corpuscles (light touch).
Adaptation:
Sensory receptors can decrease sensitivity to constant stimuli, facilitating attention to changes.
Regeneration of Nerve Fibers:
PNS has regenerative capacity due to Schwann cells; CNS has limited regeneration capacities.
Plexuses: Locations include:
Cervical Plexus: Innervates neck and diaphragm.
Brachial Plexus: Innervates upper limbs.
Lumbar Plexus: Innervates lower limbs.
Sacral Plexus: Innervates pelvic region and lower limbs.
Motor Control Levels:
Cortex: Higher control, planning of movements.
Basal Ganglia: Coordination and regulation of movement.
Cerebellum: Fine-tuning and balance.
Reflex Arc Components:
Sensory receptor, sensory neuron, integration center (CNS), motor neuron, effector.
Muscle Spindles and Golgi Tendon Organs:
Muscle Spindles: Detect muscle stretch and send signals to spinal cord.
Golgi Tendon Organs: Monitor tension in muscles.
Stretch and Crossed Extensor Reflexes:
Stretch Reflex: Maintains muscle tone and posture (e.g. patellar reflex).
Crossed Extensor Reflex: Allows adjustment of opposite limb during withdrawal from stimulus (e.g. stepping on a nail).
Abnormal results in superficial reflex tests can indicate neurological issues.