Impact of substance use on population health
Definition of disease burden related to substance use
Application of evidence-based interventions for harm prevention
Population-level strategies for substance use prevention and treatment
2021: Over 100,000 U.S. deaths from opioid overdoses
Alcohol accounts for over 5% of global disease burden
22.3% of the global population uses tobacco
Substance Use Defined: Use of psychoactive substances affecting the CNS leading to altered mood and perception.
Substance use varies by:
Quantity and type of consumption
Cultural norms
Socioeconomic status
Quality of substances (e.g., toxic illicit alcohol)
Categories:
Stimulants
Depressants
Inhalants
Dissociative anesthetics
Narcotics
Hallucinogens
Cannabis
Stages include:
Abstinence
Low Risk Use
At Risk Use
Substance Use Disorder
Adverse Health Consequences
Economic resources limit prevention policy enforcement.
Advocate understanding of context, disease burden, and evidence-based interventions.
Increases risks for health issues, crime, and adverse environmental factors.
Range of harms: Acute (immediate effects) and Chronic (long-term effects).
Acute Harm:
AlcoAlcohol: Liver diseasehol: Poisoning, impaired judgment
Opioids: Overdose, respiratory depression
Cocaine: Heart attacks
Methamphetamine: Psychosis
Chronic Harm:
Opioids: Addiction
Cocaine: Heart disease
Substance use measurement includes:
Abstinence
Low-risk use
Harm-related use
Risk is not clearly defined.
Key U.S. surveys:
Behavioral Risk Factor Surveillance System (BRFSS)
National Survey on Drug Use and Health (NSDUH)
National Epidemiologic Survey on Alcohol and Related Conditions (NESARC)
Excessive Use:
Men: >15 drinks/week
Women/Adults >65: >8 drinks/week
Heavy Drinking:
Men: >5 drinks/occasion
Women/Adults >65: >4 drinks/occasion
No safe level of alcohol during pregnancy.
Fetal alcohol spectrum disorders (FASD) occur from prenatal exposure.
Risks vary by age due to metabolic changes.
Influencing factors include:
Environment
Gender
Socioeconomic status
Preference to view substance use disorder (SUD) as harm-related rather than purely clinical.
Maladaptive substance use causing significant impairment or distress, classified as moderate or severe based on:
Physiological dependence
Tolerance
Withdrawal symptoms
Primary Prevention: Education programs, public awareness campaigns, and legislation.
Secondary Prevention: Screening, early identification, and harm reduction strategies.
Tertiary Prevention: Rehabilitation, support groups, and social support services.
Aims to reduce harm related to at-risk substance use without solely focusing on abstinence.
Strategies target community-level impact.
Facilities that provide a safe environment and medical supervision for drug use to prevent overdose and disease transmission.
Benefits include reduced overdose rates and increased treatment access.
Linked to over 200 conditions and responsible for 5.3% of global deaths.
Affects vulnerable populations, including pregnant women and older adults.
Universal screening method for alcohol use harm.
Screening: Assessment of substance use patterns.
Brief Intervention: Short conversations to encourage behavior change.
Referral to Treatment: Connecting individuals to specialized treatment options.
Responsible for over 8 million deaths annually.
Preventable death leading cause in the U.S. from smoking and exposure to secondhand smoke.
Assessment includes quantity, frequency, and history of use.
Cessation strategies involve healthcare provider support and counseling.
WHO's MPOWER framework outlines actions to reduce tobacco use at individual and population levels.
Rising opioid overdose rates noted (100,306 deaths in 2021).
Medication-Assisted Treatment (MAT) effective for OUD and AUD in comprehensive treatment settings.
Integrates medication with counseling to treat SUD, emphasizing improved survival rates and reduced illicit use.
Easily manufactured, associated with severe health consequences, including mental illness and environmental impact.
Vary by drug type; rebound effects are common post-use, increasing risks for comorbid disorders and adverse consequences.
Principles of community care, types of substance use, and prevention methods.