Respiratory System

  • Primary Purpose of the Respiratory System:

    • Continuous absorption of oxygen (O) & excretion of carbon dioxide
    • Filtering air to prevent allergens & microbes from reaching the lungs
    • Transporting oxygenated blood to tissues
    • Warming & humidifying inspired gas
  • Trachea Branch Point:

    • Branches into two main stem bronchi at the "Carina"
  • Aspirated Objects:

    • Most aspirated objects/fluids end up in the right main stem bronchus because:
    • Right bronchus is larger & more in-line with the trachea
  • Left Lung Features:

    • The left bronchus is shorter than the right
    • Anatomical correspondence of the left lung to the right lung's middle lobe is the "Lingula"
  • Terminal Bronchioles Characteristics:

    • Smallest purely conducting airways
    • Average 3 to 4 mm in diameter
    • Generally five divisions below segmental bronchi
  • Flow Type Beyond Terminal Bronchioles:

    • Laminar flow
  • Mucosa Cell Types:

    • Most common in larger airways: Pseudostratified ciliated columnar epithelium
  • Effects of Histamine Release:

    • Causes bronchoconstriction (1)
  • Functions of Airway Mucus:

    • Protects airways from water loss & toxic particles
    • Traps inhaled contaminants
  • Ciliary Action:

    • "Mucociliary escalator" - forward stroking of cilia
  • Classification of Airway:

    • From nares to terminal bronchioles is called "Conducting airways"
  • Definition of Acinus:

    • Comprises all structures distal to a terminal bronchiole
    • Represents the functional unit of the lungs
  • Alveolar Cells:

    • Type I cells cover over 90% of the alveolar-capillary membrane
    • Type II cells secrete pulmonary surfactant
  • Surfactant Importance:

    • Promotes lung stability
  • Phagocytic Cells in Lungs:

    • Alveolar macrophages ingest foreign material
  • Collaterals for Ventilation:

    • Canals of Lambert & Pores of Kohn
  • Thoracic Anatomy:

    • Midclavicular line = anatomical landmark
    • Thin serous membrane on thoracic wall: Parietal pleura
  • Sternum Parts:

    • Upper portion: "Manubrium"
  • Diaphragm Movement:

    • During tidal breathing: Pulled down 1 to 2 cm
  • Diaphragm Innervation:

    • Nerves arise from spinal nerves C3 to C5
  • Accessory Muscles of Inspiration:

    • External intercostals & scalene muscles elevate ribs
  • Pleural Fluid Function:

    • Reduces friction
  • Chest Radiograph Observations:

    • Costophrenic angle blunted mainly by excess fluids
  • Pulmonary Circulation:

    • Delivers oxygenated blood to the heart (via left atrium)
  • Airway Opening in Unconscious Patient:

    • Neck extension needed
  • Trachea Length:

    • Approximately 10 to 12 cm in adults
  • Costal Pleura & Diaphragmatic Pleura Angle:

    • Known as Costophrenic angle.