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Trematodes (Flukes)

  • Small, flat, leaf-like worms, flattened dorso-ventrally with no body cavity

  • Body mass consists of: mesodermal parenchyma, where internal organs are embedded

  • Oral and ventral suckers that help attach to the host

  • Infest various organs of the human host

    • e.g. intestinal veins, urinary bladder, liver, lung

  • Use freshwater snails as an intermediate host

Liver Fluke

Classification

Domain: Eukaryote

Kingdom: Animalia

Phylum: Platyhelminthes (flatworms)

Class: Trematodes (flukes)

Hermaphroditic Flukes

Hermaphrodite: organism that has both kinds of reproductive organs and can produce both gametes associated with male and female sexes

Life cycle beginning: hermaphroditic adult fluke produces eggs in the human (definitive host)

  • eggs are excreted into the environment

  • first larval stage (miracidium) develops inside the eggs

  • the larvae seek out and infect suitable snail species (first intermediate host)

  • asexual reproduction occurs in the snail

    • several intermediate development forms can be distinguished (sporocyst, redia) and the final larval stage (cercaria)

  • leave the snail and seek out second intermediate host

    • a fish or crustacean

  • in the second intermediate host, the cercaria form cysts called metacercaria excysts

  • if the infected raw or under-cooked fish or crustacean is eaten by a human, the metacercaria excysts, and the fluke invades tissues (such as the lung or liver) and begins producing eggs

Sexual Flukes (Schistosomes)

  • called “blood flukes”

  • have separate distinct sexes

  • similar life cycle to hermaphroditic flukes

  • only one intermediate host (snail)

  • acquired by: schistosome cercaria directly penetrating the skin in contaminated rivers and lakes

  • adult schistosomes take up residence in various abdominal veins

  • in fresh water, the organisms infect snails (in which they multiply)

    • cercaria are released into the fresh water

Trematodes Include

  • Hepatic/liver flukes

    • Fasciola hepatica

  • Intestinal flukes

    • Fasciolopsis buski

    • Heterophyes heterophyes

  • Lung flukes

    • Paragonimus westermani

  • Blood flukes

    • Schistosoma haematobium

    • Schistosoma mansoni

LA

Trematodes (Flukes)

  • Small, flat, leaf-like worms, flattened dorso-ventrally with no body cavity

  • Body mass consists of: mesodermal parenchyma, where internal organs are embedded

  • Oral and ventral suckers that help attach to the host

  • Infest various organs of the human host

    • e.g. intestinal veins, urinary bladder, liver, lung

  • Use freshwater snails as an intermediate host

Liver Fluke

Classification

Domain: Eukaryote

Kingdom: Animalia

Phylum: Platyhelminthes (flatworms)

Class: Trematodes (flukes)

Hermaphroditic Flukes

Hermaphrodite: organism that has both kinds of reproductive organs and can produce both gametes associated with male and female sexes

Life cycle beginning: hermaphroditic adult fluke produces eggs in the human (definitive host)

  • eggs are excreted into the environment

  • first larval stage (miracidium) develops inside the eggs

  • the larvae seek out and infect suitable snail species (first intermediate host)

  • asexual reproduction occurs in the snail

    • several intermediate development forms can be distinguished (sporocyst, redia) and the final larval stage (cercaria)

  • leave the snail and seek out second intermediate host

    • a fish or crustacean

  • in the second intermediate host, the cercaria form cysts called metacercaria excysts

  • if the infected raw or under-cooked fish or crustacean is eaten by a human, the metacercaria excysts, and the fluke invades tissues (such as the lung or liver) and begins producing eggs

Sexual Flukes (Schistosomes)

  • called “blood flukes”

  • have separate distinct sexes

  • similar life cycle to hermaphroditic flukes

  • only one intermediate host (snail)

  • acquired by: schistosome cercaria directly penetrating the skin in contaminated rivers and lakes

  • adult schistosomes take up residence in various abdominal veins

  • in fresh water, the organisms infect snails (in which they multiply)

    • cercaria are released into the fresh water

Trematodes Include

  • Hepatic/liver flukes

    • Fasciola hepatica

  • Intestinal flukes

    • Fasciolopsis buski

    • Heterophyes heterophyes

  • Lung flukes

    • Paragonimus westermani

  • Blood flukes

    • Schistosoma haematobium

    • Schistosoma mansoni