Microbiome: Also known as Microbiota & Normal flora
-Organisms that colonize the body's surface without causing
-Microorganisms that live in & on the body
2 types -Resident Microbiota: Normal Microbiota throughout life; mostly commensal
-Transient Microbiota: Remain in body for short period. Found in same areas as resident.
-cannot persist in body b/c: competition from other microorganisms, elimination by the body's defense cells, chemical or physical body changes
- acquisition : development in womb
development: during birthing process, first meals (human milk microbiota)medical Staff, parents (get their microbiota on baby)
Resident microbiota established first few months of life
-opportunistic Pathogens: Normal Microbiota that cause disease under certain circumstances.
-conditions that provide opportunities: introduction of germ that you normal microbiota into unusual body site, immune suppression, Changes in normal Microbiota, Stressful conditions
-Most pathogen can’t survive for long outside their host
(1)Animal reservoir
-Zoonoses: disease naturally spread animal human
-aquired through: direct contact with animal or its Waste, eating animal, blood sucking arthropods
-human normally dead-end host /does not spread;
-ex: disease -Animal-how
Helminthic: tapeworm-dog-larvae transmitted in dog Saliva
~ protozoan: Malaria-Monkeys -Mosquitobite (plasmodium)
-fungal: Ringworm-domestic Animals-direct Contact.
~ Bacterial: Plaque-Rodents -Flea bites
-viral: Rabies-bats/Skunks/foxes /dogs-bite.