Virology Practice Questions

Virology Practice Questions: Section 1

Question 1: Lettuce-borne Outbreak in California

• Scenario: An outbreak in California affected 60 people, linked to lettuce from a local farmer’s market.
• Symptoms: Fever, chills, body aches, fatigue, nausea, vomiting, and mild jaundice, appearing 3-4 weeks post-consumption.
• Lab Findings: Elevated serum levels of alanine transferase (ALT).
• Outcome: Patients recovered without complications.
• Question: What is the most likely cause?
  • A. Hepatitis A virus
  • B. Hepatitis B virus
  • C. Hepatitis C virus
  • D. Rotavirus
  • E. Norovirus

Question 2: Hepatitis B Surface Antigen Antibodies

• Scenario: A 20-year-old female student has IgG antibodies to hepatitis B surface antigen during a blood drive.
• Question: What is the most appropriate conclusion?
  • A. She has acute hepatitis B
  • B. She has chronic hepatitis B
  • C. She has developed cirrhosis
  • D. She has a 10% chance of developing liver cancer
  • E. She has been vaccinated against hepatitis B

Question 3: Rotavirus Gastroenteritis in Developing Countries

• Problem: Hundreds of thousands of children die from rotavirus gastroenteritis in developing countries.
• Cause of Death: Severe dehydration due to malabsorption.
• Question: Which factor plays a crucial role in the pathogenesis of infectious diarrhea?
  • A. Viral infection of crypt cells, leading to malabsorption