Define the concept of mobility
Describe the scope of mobility
Describe the requirements for mobility and the function of neurologic and musculoskeletal structures related to mobility
Identify conditions causing impaired mobility
Identify risk factors for impaired mobility in older adults
Describe the pathophysiology of osteoporosis
Mobility: The state or quality of being mobile or movable.
Essential for performing Activities of Daily Living (ADLs) such as:
Eating
Dressing
Walking
Categories:
Full mobility
Impaired mobility
Immobility
Impairment in mobility can include:
Limitation in physical movement
Inability to perform gross or fine movements and coordination
Modifications in mobility can be:
Transient
Recurring
Permanent
Common causes of immobility include:
Stroke
Fractures
Multiple sclerosis
Trauma
Morbid obesity
Aging impacts mobility due to changes in skeletal, muscular, and nervous systems.
Complete the concept triangle demonstrating relationships between:
Mobility
Perfusion
Gas exchange
Age-related changes in:
Neurologic function
Musculoskeletal function
Other body systems (e.g., circulation, respiratory)
Caused by:
Neurologic conditions
Brain, spinal cord, nerves
Musculoskeletal conditions
Skeletal (cartilage, tendons, ligaments)
Muscle conditions
Joint conditions
Common consequences can include:
Increased risk of falls
Muscle atrophy
Contractures
Situations where immobility is beneficial should be considered (e.g., post-surgery for healing).
Types of bone structures:
Concentric lamellae
Interstitial lamellae
Trabecular (spongy) bone
Osteons
Components:
Periosteum, perforating canal, central canal, arteries, and veins.
Process: Bone resorption and deposition.
Bone remodeling cycle relevant to maintaining bone health.
Key regulators include:
Nutrients (minerals, vitamins)
Hormones (parathyroid hormone, Vitamin D, calcitonin)
Physical activity influences bone density and strength.
Role of PTH and Calcitonin:
PTH promotes Ca2+ release into blood and reabsorption from urine.
Calcitonin inhibits Ca2+ release by osteoclasts.
Achieved by age 30 after a period of higher bone formation than resorption.
Importance of building strong bones in childhood and adolescence to prevent osteoporosis.
Multifactorial disease characterized by:
Absolute reduction in total bone mass
Imbalance in bone remodeling
Risk factors: Aging, being female, genetic predisposition, lifestyle factors, hormonal changes.
Affects at least 1 in 3 women and 1 in 5 men.
2 million Canadians affected; over 80% of fractures in individuals 50+ are osteoporotic.
Significant mortality risk (28% of women, 37% of men post-hip fracture).
Modifiable risk factors: Lifestyle choices affecting bone health.
Non-modifiable risk factors: Age, gender, family history.
After age 30, resorption exceeds formation.
Men generally start with higher bone mass and lose it more slowly than women.
Men typically have higher density due to hormonal factors.
Ethnic variations exist in bone mass.
Post-menopausal and age-related factors contribute to increased bone loss.
Osteopenia and subsequent osteoporosis can develop due to these factors.
Estrogen inhibits osteoclast activity, slowing bone resorption.
Rapid loss during early menopause.
Structural changes in both compact and spongy bone observed during osteoporosis.
Based on Bone Mineral Density (BMD) measurements using T scores to assess risk.
Weakening of bones increases risk of fractures, especially in the spine, proximal femur, and distal radius.
Osteoporosis directly affects mobility due to structural weakening and related fractures.
Prepare for Class 2 on Friday with any questions or topics for discussion.