Chapter 10: Cell Division & Mitosis

  • Functions of cell division

    • Preproduction

    • Growth

    • Repair

  • Cell Cycle shows events

    • Interphase- Preparation period mitosis

    • G1- Doubling of organelles, cell will get bigger

    • S- Synthesis; Synthesis DNA, DNA replicated

    • G2- Production of protein for mitosis

    • Mitosis

  • Cell cycle arrest at specific checkpoint

  • G1/S Checkpoint

    • Chemicals can stop cell cycle

    • PH3 protein- can stop cell cycle to repair it

      • Apoptosis = program soul death

    • Rb protein= Stop cell cycle can regulate by closing of production of proteins need for cell division

  • G2/M Checkpoint- Have to be passed in order to move to mitosis

    • Mirotic

  • Internal control system regulates cell cycle

  • Cyclins and CDR= Proteins and enzymes together to control the cycle cell

    • They phosphorylate proteins

    • Specific CDK target certain protein

  • Key events = DNA replication, mitosis, cytokinesis

  • Mitosis and Cytokinesis

    • Chromatin- Uncondensed, Chaotic and Organized

    • Chromosomes

      • Diploid= 2(N)= 46

      • Haploid= (IN)= 23

  • Somatic cells undergo mitosis to maintain chromosome #’s constant

  • Phase of cell cycle

    • Interphase

  • Prophase- Chromosome are visible, membrane breakdown the spira

  • Metaphase- chromosomes line up in the middle of the cell, along the metaphase plate, preparing for separation.

  • Anaphase- the sister chromatids are pulled apart to opposite sides of the cell by the spindle fibers, preparing the cell for division.