Vitamins
· Vitamin A – maintains health of epithelial tissue/skin, important for gene transcription, re-synthesis of rhodopsin
· Vitamin D – increases blood calcium level by increasing Ca2+ absorption, important for gene transcription
· Vitamin E – halts lipid peroxidation
· Vitamin K – carboxylates glutamate (in clotting factors) which allows calcium to bind, bone health through the protein osteocalcin
· Vitamin C – allows collagen strands to bind, part of carnitine + serotonin + norepinephrine synthesis, needed for regeneration of vitamin E and niacin
· B vitamins:
- Thiamin – as TPP is a part of dehydrogenase enzymes
- Riboflavin – part of FADH2 and FMN, donates electrons at complex II in ETC
- Niacin – donated electrons at complex I in ETC, needed for re-synthesis of glutathione (antioxidant)
- Pantothenic acid (B5) – part of CoA
- B6 – reduces homocysteine levels, coenzyme for transamination reactions
- Biotin (B7) – part of carboxylase enzymes
- Folate (B9) – reduces homocysteine levels, nucleotide synthesis
- B12 (cobalamin) – reduce homocysteine levels, part of myelin sheath of neurons
- Choline (part of B4) – part of acetylcholine, part of phosphatidylcholine in membranes and lipoprotein
Niacin (B3) – essential for the synthesis of NAD and NADP, which are crucial for energy metabolism