Chapter 8: Aging
In this Chapter…
- Aging in different ways
- What we know and don’t know about aging
Aging in Different Ways
- Severe declines in memory, intelligence, verbal fluency, etc. are not a part of normal aging
- Effects of age on brain function are very subtle and selective
- Once most people reach their 70s, they may find themselves forgetting names, phone numbers, etc.
- The response to conflicting information slows down as well
- Dementia: a progressive and severe impairment in mental function that interferes with activities of daily living
- Types of dementia:
- Alzheimer’s disease- the most common
- Cerebrovascular disease
- Pick’s disease
- Lewy body disease
What we know and don’t know about aging
- The brain reaches its maximum weight near the age of 20
- Subtle changes in the chemistry and structure of the brain begin in midlife for most people
- The brain is at risk of losing some neurons but not widespread neuron loss
- This distinguishes normal aging from neurodegenerative disease
- After the damage or loss of neurons, the remaining healthy ones are able to expand dendrites and fine-tune connections with other neurons
- If the cell body is intact, the damaged neuron can induce changes in its axon and dendrites to regrow them
- The brain cannot generate new neurons
- Not many stem cells exist in the brain
- The stem cell number in the brain actually decreases as a person ages
Changes in Intellectual Capacity
- As people age, the speed of carrying out tasks is slower but their vocabulary improves
- There is an increase in the type of intelligence relying on learned or stored information but a decrease in the type that depends on the ability to deal with new information
- The brain is only as resilient as its circuitry
- When the circuitry breaks down, neurons adapt by expanding their roles
- Larger portions of the brain are “recruited” so older people can reach performance levels similar to younger adults
- Motor learning generates new synapses
- This is how aerobic exercise improves cognitive performance
- Many theories for normal brain aging:
- Specific “aging genes” turned on
- Accumulation of mutations/other types of DNA damage
- Hormonal influences
- The immune system has gone awry
- Accumulation of oxidative damage caused by free radicals
- Free radicals: cell byproducts that destroy fats and proteins vital to cellular functions
- Physical and mental exercise are both effective means of slowing the effects of brain aging