Unit 2

  • Cells

    • Characteristics of LIving things

      • Made of cells

      • Respond to stimuli

      • Adapt to the environment

      • Growth and reproduction

      • Use energy

      • Maintain homeostasis

    • Cell theory

      • All living things are made of cells.

      • Cells are the basic unit of structure and function of living things.

      • All cells come from other cells.

    • Types of Cells

      • Prokaryote

        • 1st cells

        • Evolved first on the Earth

        • Very simple

        • Lack most organelles

        • Example: Bacteria

      • Eukaryote

        • Evolved from prokaryotes

        • Complex

        • True nucleus

        • Have various organelles

        • Example: plant, animal, fungus and protists

    • Prokaryote Bacteria

      • Cell Wall: Made of peptidoglycan: uses for support (difference between a Gram + and Gram -

      • Cell Membrane: Regulates what enters and leaves the cell (homeostasis)

        Ribosomes: Site of protein synthesis

        • (no membrane), Different size than eukaryotes

      • Nucleoid: Region of the cell that the DNA is located

      • Plasmids: small circular piece of DNA that bacteria can exchange

      • Pili: Connect to other Bacteria to exchange plasmids

      • Flagella: Long tail that aids in movement.

  • Organelles

    • Cell Wall

      • All cells except Animals

      • Protects and supports the cell

      • Made out of carbohydrates

    • Cell Membrane

      • All cells

      • Regulates what goes into and out of the cell

    • Cytoplasm

      • All cells

      • Liquid part of the cell (Mostly water)

      • Cytoskeleton: protein network that holds the organelles in place

    • Nucleus

      • All Cells except bacteria

      • Contains the DNA and nucleolus

    • Nucleolus

      • All Cells except bacteria

      • found in the nucleus and makes ribosomes

    • Ribosome

      • ALL CELLS

      • Not membrane bound

      • Site where proteins are made

      • Main function of the cell is to make proteins

    • Endoplasmic Reticulum

      • All cells except bacteria

      • allows for the transport within the cell

      • Smooth = no ribosomes

      • Rough = ribosomes

    • Golgi Apparatus

      • All cells except bacteria

      • site where proteins are modified prior to use

    • Chloroplast

      • Only in plant and algal cells

      • site of photosynthesis 

    • Mitochondria

      • Found in all cells except bacteria

      • Site where the the energy of glucose is converted into ATP

    • Lysosome

      • All cells except Bacteria

      • Contain enzymes to allow for the digestion of molecules within the cell

    • Vacuole

      • All cells except bacteria

      • Very large in plant cells

      • Storage sacs for water, salts and minerals

    • Centrosomes

      • Found in animal cells

      • Make spindle fibers to use in cell division

  • Cell Membrane

    • Cell Membrane

      • Made of Biomolecules

        • Carbohydrates

        • Lipids

        • Proteins

      • Selectively permeable - only certain material is able to pass

      • All cells contain a cell membrane

      • All organelles except ribosomes contain a membrane

    • Lipids

      • Phospholipids

        • Main body of the cell membrane

          • Hydrophilic Head

            • Contains a Phosphate

            • LIkes water

            • Polar

          • Hydrophobic Tail

            • Made of 2 fatty acids

            • Doesn’t like water

            • Non-polar

        • Bilayer

          • The fatty acid tails point towards each other

          • Phosphate heads are outwards by the watery fluids

          • Only small nonpolar molecules can easily cross between the fatty tails

        • Cholesterol

          • Fits in between the phospholipids

          • Holds the phospholipids together without making it too stiff

          • Prevents membrane from freezing

    • Proteins

      • Large molecules that are embedded throughout the membrane

      • Many different types

        • Channel Proteins: move large or polar molecules across the membrane

          • These will be open from one side of the membrane to the other

        • Carrier proteins: binds to material and moves them through a channel protein

          • Acts like a key to open the channel protein to move the material across

    • Carbohydrates

      • Glycolipids

      • Glycoproteins

      • Function

        • Cell communication

          • Tells neighboring cells that it needs something

          • Tells neighboring cells that it is going to divide

        • Cell recognition

          • How cells know that cell belongs to you

          • How cells know that cell belongs to an organ

          • Your body can recognize non-self cells and mark them for death

    • What factors influence how molecules move across the cell membrane?

      • Size

        • Small can fit through the phospholipids

        • Large go through a protein

      • Polarity (charge)

        • Nonpolar = phospholipid

        • Polar = protein

      • Shape

        • Proteins work like a lock and key

      • Concentration

        • The greater the concentration difference, the faster diffusion will occur

  • Types of Transport

    • Passive Transport

      • Movement of molecules from an area of high concentration to an area of low concentration

      • With the concentration gradient

      • Across the membrane

      • Until it reaches equilibrium

        • All the molecules are equally spaced

        • Molecules continuously move

      • No energy is required to move across the membrane

      • Examples

        • Diffusion

          • Movement of molecules/material through phospholipids

          • HIgh concentration to low concentration

          • Reach equilibrium

          • No energy required

        • Facilitated diffusion

          • Diffusion with assistance from a membrane protein

          • Still from high to low concentration

          • No energy required

          • Example

            • Glucose

            • Na+

        • Osmosis

          • Facilitated diffusion of water only

          • Water moves toward solutes

          • Reach equilibrium

          • No energy

          • Really water moves in response to solute concentration

          • Solute is the stuff dissolved into the water

          • Water wants to dilute the solute, so it moves to the higher solute concentration

          • Example situation

            • Hyperosmotic

              • Means more solute on the outside of the cell

              • Water move out of the cell

              • Cell shrinks

              • Also known as plasmolysis

            • Hypoosmotic

              • Means less solute outside of the cell

              • More solute inside of the cell

              • Water moves in

              • Cell will expand

              • Also known as Turgor Pressure

                • Helps plants to stand tall

            • Isosmotic

              • Equal amount of solute in and out of the cell

              • Equal movement of water in and out of the cell

              • No net loss or gain to cell size

    • Active transport

      • Molecules move against the concentration gradient

        • Low concentration to High concentration

      • Never reach equilibrium-actively working AGAINST equilibrium

      • Requires a protein

      • Requires energy

      • Examples:

        • Sodium-potassium pump = used in nerve function and muscle cell contractions

        • Electron Transport Chain = used in photosynthesis and Cell Respiration

        • Endocytosis = bring materials into a cell

        • Exocytosis = removal of material from the cell