main charactertistics of life order, evolutionary adaptation, response to the environment, regulation, energy processing, reproduction, growth & development
taxonomy from most inclusive to least inclusive:
domain → kingdom → phylum → class → order → family → genus → species
levels of organization from most inclusive to least inclusive:
biosphere → ecosystem → community → population → organism → organs/organ systems → tissues → cells → organelles → molecule
central dogma DNA transcripts into RNA, which translates to proteins
adaptation an inherited trait that enhances individual’s ability to survive and reproduce in a particular environment OR a change occurring in a population in response to a changing environment
natural selection the survival of certain organisms with traits necessary for survival
conditions necessary: variation, overproduction, and heritability
theory a potential reason for a hypothesis
prediction testable statement that could support the hypothesis (if/then format)
control group a group of the experiment held to every condition but the testable variable
experimental group a group of the experiment held to every condition including the testable variable
independent variable manipulated/changed by the experimenter
dependent variable measured during the experiment; the result of the independent variable
controlled variables variables held constant throughout the experiment
placebo a variable with no real effect designed to look like the actual variable being tested
inductive reasoning used to come up with a general hypothesis
deductive reasoning used to come up with a specific prediction
elements pure substance that cannot be broken down into other types of substances. the most important ones for life are carbon, hydrogen, oxygen, nitrogen, phosphorous, and sulfur
atom smallest unit of matter that retains properties of a given element
protons a subatomic particle with a positive charge
electrons a subatomic particle with a negative charge
neutrons a subatomic particle with neutral charge
valence the bonding capacity of an atom. the number of electrons required to complete the atom’s outermost shell
ionic bond an electrical attraction between ions (cation and anion)
ex: NaCl
must be with a metal and a nonmetal.
covalent bond involves the sharing of electrons. strength INCREASES from a single to a double bond, double to triple, etc.
this is the strongest bond
non-polar covalent bond involves the equal sharing of electrons
ex: O2, N2, CH4
polar covalent bond involves the unequal sharing of electrons
ex: H2O
hydrogen bond interaction between a Hydrogen atom that has a covalent link with an electronegative atom (F, N, or O) and another electronegative atom
ex: bond between a H2O molecule and a NH3 molecule
intermolecular force a force that exists between different molecules
intramolecular force a force that holds atoms together within a molecule
universal solvent a property of water: dissolving more substances than any other liquid
adhesion a property of water: sticking to and interacting with other surfaces
cohesion a property of water: interacting with itself, this property allows for surface tension
high specific heat a property of water: maintaining temperature
pH a measure of hydrogen ion concentration in a solution
pH equations pH = -log[H+]
[H+]*[OH-] = 10^-14
increases if a pH of solution decreases, the H+ concentration of the solution ___
tetravalent carbon is chemically versatile because it is ___ (meaning it can form up to 4 covalent bonds)
functional groups, 3D shape the function of a biological molecule is determined by its ___ and its overall ___
isotope a variant of an atom of a chemical element that has the same # of protons but a different number of neutrons, resulting in a different atomic mass
hydroxyl general molecular composition: -OH
compound name: alcohols
carbonyl general molecular composition: >C=O
compound name: ketones/aldehydes
ketones a carbonyl group that is in the middle/inside of a molecule
aldehydes a carbonyl group that is on the end of a molecule
carboxyl general molecular composition: -COOH
compound name: organic acids
amino general molecular composition: -NH2
compound name: amines
sulfhydryl general molecular composition: -SH
compound name: thiols
phosphate general molecular composition: -OPO3^-2
compound name: organic phosphates
methyl general molecular composition: -CH3
compound name: methylated compounds
isomers have the same molecular formula but different structures and properties
structural isomers differ in covalent arrangements of the atoms and/or location of double bonds
cis-trans isomers same covalent partners but differ in spatial arrangement about a double bond
cis isomers the covalent partners are on the same side of the molecule (such as both being at the top)
trans isomers the covalent partners are on different sides of the molecule (diagonal from each other)
enantiomers mirror images of each other, differ in spatial arrangement around an asymmetric carbon
monomer a single repeating subunit
polymer a long molecule consisting of many similar or identical subunits (monomers)
dehydration synthesis water molecule is lost when a covalent bond forms between two monomers
hydrolysis water is added, covalent bond is broken, and hydrogen and oxygen atoms from water are added to the monomers
polysaccharide a true polymer of carbohydrates, includes starch, glycogen, cellulose, and chitin
monomer of carbohydrates contains a hydroxyl group (OH) and a carboxyl group (-COOH)
examples include: glucose, fructose, galactose
glycosidic linkage the bond between carbohydrate monomers
maltose a disaccharide: forms with glucose + glucose
sucrose a disaccharide: forms with glucose + fructose
lactose a disaccharide: forms with glucose + galactose
starch a polysaccharide that functions as storage in plants. an alpha polymer of glucose
glycogen a polysaccharide that functions as storage in animals. an alpha polymer of glucose
cellulose a polysaccharide that functions as structure in plants. a beta polymer of glucose
chitin a polysaccharide that functions as structure in animals. a beta polymer of glucose
lipids the only group of large biological molecules that is not a true polymer
components of lipids contains glycerol and fatty acids
triacylglycerol a lipid that contains one glycerol and 3 fatty acids
saturated fatty acids these are fatty acids that do not contain double bonds
unsaturated fatty acids these are fatty acids that do contain double bonds
phospholipids a lipid that contains 1 glycerol, 2 fatty acids, and a phosphate group
steroids a lipid with 4 fused carbon rings with chemical groups attached
cholesterol a component of membranes and precursor for steroid hormones
ester linkage the bond connecting glycerol to fatty acid
polypeptides the polymer of proteins
components of proteins contains an amino group, a carboxyl group, and an R side chain
nonpolar side chain these are hydrophobic and are made up of mostly carbon and hydrogen atoms.
polar side chain these are hydrophilic and contain electronegative atoms such as OH, NH2, or SH
acidic side chain these are side chains with negatively charged atoms
basic side chains these are side chains with positively charged atoms
primary structure the sequence of amino acids
secondary structure alpha helices and beta sheets due to hydrogen bonding in backbone
tertiary structure the overall 3D structure of a protein
quaternary structure proteins consisting of two or more polypeptide chains
peptide bond the bond between protein monomers
nucleotides the monomer of nucleic acids
components of nucleic acids contains a nitrogenous base, a phosphate group, and a pentose sugar
deoxyribose the sugar of DNA
DNA contains deoxyribose sugar. the nitrogenous base is C, G, A, T.
usually double-stranded
stores hereditary info
ribose sugar of RNA
RNA contains ribose sugar, nitrogenous base is C, G, A, U
usually single-stranded
needed for gene expression, including carrying instructions from DNA to ribosomes
light microscopy uses light to view specimen. can view live cells
electron microscopy uses beams of electrons to view specimen. cannot view live cells
scanning electron microscopy (SEM) shows the surface (3D) of specimen
transmission electron microscopy shows the internal structure of specimen
nitrogenous bases cytosine, adanine, thymine, guanine
phosphodiester bond the bond between monomers for nucleic acids
prokaryotes contains a nucleoid region, is usually smaller, and is bacteria. also has a cell wall, plasma membrane, DNA, ribosomes, and cytosol
eukaryotes contains membrane-bound organelles, a nucleus, cell wall, plasma membrane, DNA, ribosomes, and cytosol
animal cells contains lysosomes and a centrosome. also has a cell membrane, nucleus, rough and smooth ER, Golgi apparatus, ribosome, mitochondrion, and a vacuole
plant cells contains cell wall, chloroplast, and a central vacuole. also has a cell membrane, nucleus, rough and smooth ER, Golgi apparatus, ribosome, mitochondrion, and a vacuole
plasma membrane selectively permeable membrane, encloses the cell, protects cell
nucleus storage sites of genetic material, headquarters of the cell
ribosome an organelle that synthesizes protein
rough ER produces protein, studded with ribosomes hence “rough”
smooth ER produces and processes lipids, detoxification, calcium storage
Golgi apparatus packages and transports proteins, synthesizes, packages, sorting and modifies cells
peroxisome decomposes hydrogen peroxide into water and oxidizes fatty acids
mitochondria powerhouse of the cell; energy production and cellular respiration
central vacuole stores nutrients, water disposal, storage, plant cell growth
chloroplasts photosynthesis, converting CO2 and H2O to glucose and oxygen
lysosomes recycles and breaks down waste in cells
cytoskeleton contains microtubules, microfilaments, and intermediate filaments
microtubules consists of tubulin.
movement and motility, cell division
ex: flagella and mitotic spindle
flagella sperm tail (a microtubule)
mitotic spindle carries out mitosis and meiosis (a microtubule)
microfilaments consists of actin.
muscle contraction, cell division, amoeboid movement
ex: cleavage furrow, flexing muscles
intermediate filaments consists of keratin, family proteins
anchors cells, nuclear lamina, formation
plasmodesmata only in plants. forms connections for small molecules to pass through channels
tight junctions in animals. creates an impenetrable barrier that prevents leakage
gap junctions in animals. forms connections for small molecules to pass through channels
desmosomes in animals. forms anchoring connections supporting cells under stress
endosymbiotic theory mitochondria and chloroplasts evolved from free-living prokaryotic cells
double both chloroplasts and mitochondria have a ___ membrane, circular DNA, cell membranes, and reproduce independently
membrane enfolding hypothesis proposes that the internal membrane systems found in eukaryotic cells originated from the plasma membrane of an ancestral prokaryotic cell folding inwards
lynn margulis proposed the endosymbiotic theory
bio part 1
main charactertistics of life order, evolutionary adaptation, response to the environment, regulation, energy processing, reproduction, growth & development
taxonomy from most inclusive to least inclusive:
domain → kingdom → phylum → class → order → family → genus → species
levels of organization from most inclusive to least inclusive:
biosphere → ecosystem → community → population → organism → organs/organ systems → tissues → cells → organelles → molecule
central dogma DNA transcripts into RNA, which translates to proteins
adaptation an inherited trait that enhances individual’s ability to survive and reproduce in a particular environment OR a change occurring in a population in response to a changing environment
natural selection the survival of certain organisms with traits necessary for survival
conditions necessary: variation, overproduction, and heritability
theory a potential reason for a hypothesis
prediction testable statement that could support the hypothesis (if/then format)
control group a group of the experiment held to every condition but the testable variable
experimental group a group of the experiment held to every condition including the testable variable
independent variable manipulated/changed by the experimenter
dependent variable measured during the experiment; the result of the independent variable
controlled variables variables held constant throughout the experiment
placebo a variable with no real effect designed to look like the actual variable being tested
inductive reasoning used to come up with a general hypothesis
deductive reasoning used to come up with a specific prediction
elements pure substance that cannot be broken down into other types of substances. the most important ones for life are carbon, hydrogen, oxygen, nitrogen, phosphorous, and sulfur
atom smallest unit of matter that retains properties of a given element
protons a subatomic particle with a positive charge
electrons a subatomic particle with a negative charge
neutrons a subatomic particle with neutral charge
valence the bonding capacity of an atom. the number of electrons required to complete the atom’s outermost shell
ionic bond an electrical attraction between ions (cation and anion)
ex: NaCl
must be with a metal and a nonmetal.
covalent bond involves the sharing of electrons. strength INCREASES from a single to a double bond, double to triple, etc.
this is the strongest bond
non-polar covalent bond involves the equal sharing of electrons
ex: O2, N2, CH4
polar covalent bond involves the unequal sharing of electrons
ex: H2O
hydrogen bond interaction between a Hydrogen atom that has a covalent link with an electronegative atom (F, N, or O) and another electronegative atom
ex: bond between a H2O molecule and a NH3 molecule
intermolecular force a force that exists between different molecules
intramolecular force a force that holds atoms together within a molecule
universal solvent a property of water: dissolving more substances than any other liquid
adhesion a property of water: sticking to and interacting with other surfaces
cohesion a property of water: interacting with itself, this property allows for surface tension
high specific heat a property of water: maintaining temperature
pH a measure of hydrogen ion concentration in a solution
pH equations pH = -log[H+]
[H+]*[OH-] = 10^-14
increases if a pH of solution decreases, the H+ concentration of the solution ___
tetravalent carbon is chemically versatile because it is ___ (meaning it can form up to 4 covalent bonds)
functional groups, 3D shape the function of a biological molecule is determined by its ___ and its overall ___
isotope a variant of an atom of a chemical element that has the same # of protons but a different number of neutrons, resulting in a different atomic mass
hydroxyl general molecular composition: -OH
compound name: alcohols
carbonyl general molecular composition: >C=O
compound name: ketones/aldehydes
ketones a carbonyl group that is in the middle/inside of a molecule
aldehydes a carbonyl group that is on the end of a molecule
carboxyl general molecular composition: -COOH
compound name: organic acids
amino general molecular composition: -NH2
compound name: amines
sulfhydryl general molecular composition: -SH
compound name: thiols
phosphate general molecular composition: -OPO3^-2
compound name: organic phosphates
methyl general molecular composition: -CH3
compound name: methylated compounds
isomers have the same molecular formula but different structures and properties
structural isomers differ in covalent arrangements of the atoms and/or location of double bonds
cis-trans isomers same covalent partners but differ in spatial arrangement about a double bond
cis isomers the covalent partners are on the same side of the molecule (such as both being at the top)
trans isomers the covalent partners are on different sides of the molecule (diagonal from each other)
enantiomers mirror images of each other, differ in spatial arrangement around an asymmetric carbon
monomer a single repeating subunit
polymer a long molecule consisting of many similar or identical subunits (monomers)
dehydration synthesis water molecule is lost when a covalent bond forms between two monomers
hydrolysis water is added, covalent bond is broken, and hydrogen and oxygen atoms from water are added to the monomers
polysaccharide a true polymer of carbohydrates, includes starch, glycogen, cellulose, and chitin
monomer of carbohydrates contains a hydroxyl group (OH) and a carboxyl group (-COOH)
examples include: glucose, fructose, galactose
glycosidic linkage the bond between carbohydrate monomers
maltose a disaccharide: forms with glucose + glucose
sucrose a disaccharide: forms with glucose + fructose
lactose a disaccharide: forms with glucose + galactose
starch a polysaccharide that functions as storage in plants. an alpha polymer of glucose
glycogen a polysaccharide that functions as storage in animals. an alpha polymer of glucose
cellulose a polysaccharide that functions as structure in plants. a beta polymer of glucose
chitin a polysaccharide that functions as structure in animals. a beta polymer of glucose
lipids the only group of large biological molecules that is not a true polymer
components of lipids contains glycerol and fatty acids
triacylglycerol a lipid that contains one glycerol and 3 fatty acids
saturated fatty acids these are fatty acids that do not contain double bonds
unsaturated fatty acids these are fatty acids that do contain double bonds
phospholipids a lipid that contains 1 glycerol, 2 fatty acids, and a phosphate group
steroids a lipid with 4 fused carbon rings with chemical groups attached
cholesterol a component of membranes and precursor for steroid hormones
ester linkage the bond connecting glycerol to fatty acid
polypeptides the polymer of proteins
components of proteins contains an amino group, a carboxyl group, and an R side chain
nonpolar side chain these are hydrophobic and are made up of mostly carbon and hydrogen atoms.
polar side chain these are hydrophilic and contain electronegative atoms such as OH, NH2, or SH
acidic side chain these are side chains with negatively charged atoms
basic side chains these are side chains with positively charged atoms
primary structure the sequence of amino acids
secondary structure alpha helices and beta sheets due to hydrogen bonding in backbone
tertiary structure the overall 3D structure of a protein
quaternary structure proteins consisting of two or more polypeptide chains
peptide bond the bond between protein monomers
nucleotides the monomer of nucleic acids
components of nucleic acids contains a nitrogenous base, a phosphate group, and a pentose sugar
deoxyribose the sugar of DNA
DNA contains deoxyribose sugar. the nitrogenous base is C, G, A, T.
usually double-stranded
stores hereditary info
ribose sugar of RNA
RNA contains ribose sugar, nitrogenous base is C, G, A, U
usually single-stranded
needed for gene expression, including carrying instructions from DNA to ribosomes
light microscopy uses light to view specimen. can view live cells
electron microscopy uses beams of electrons to view specimen. cannot view live cells
scanning electron microscopy (SEM) shows the surface (3D) of specimen
transmission electron microscopy shows the internal structure of specimen
nitrogenous bases cytosine, adanine, thymine, guanine
phosphodiester bond the bond between monomers for nucleic acids
prokaryotes contains a nucleoid region, is usually smaller, and is bacteria. also has a cell wall, plasma membrane, DNA, ribosomes, and cytosol
eukaryotes contains membrane-bound organelles, a nucleus, cell wall, plasma membrane, DNA, ribosomes, and cytosol
animal cells contains lysosomes and a centrosome. also has a cell membrane, nucleus, rough and smooth ER, Golgi apparatus, ribosome, mitochondrion, and a vacuole
plant cells contains cell wall, chloroplast, and a central vacuole. also has a cell membrane, nucleus, rough and smooth ER, Golgi apparatus, ribosome, mitochondrion, and a vacuole
plasma membrane selectively permeable membrane, encloses the cell, protects cell
nucleus storage sites of genetic material, headquarters of the cell
ribosome an organelle that synthesizes protein
rough ER produces protein, studded with ribosomes hence “rough”
smooth ER produces and processes lipids, detoxification, calcium storage
Golgi apparatus packages and transports proteins, synthesizes, packages, sorting and modifies cells
peroxisome decomposes hydrogen peroxide into water and oxidizes fatty acids
mitochondria powerhouse of the cell; energy production and cellular respiration
central vacuole stores nutrients, water disposal, storage, plant cell growth
chloroplasts photosynthesis, converting CO2 and H2O to glucose and oxygen
lysosomes recycles and breaks down waste in cells
cytoskeleton contains microtubules, microfilaments, and intermediate filaments
microtubules consists of tubulin.
movement and motility, cell division
ex: flagella and mitotic spindle
flagella sperm tail (a microtubule)
mitotic spindle carries out mitosis and meiosis (a microtubule)
microfilaments consists of actin.
muscle contraction, cell division, amoeboid movement
ex: cleavage furrow, flexing muscles
intermediate filaments consists of keratin, family proteins
anchors cells, nuclear lamina, formation
plasmodesmata only in plants. forms connections for small molecules to pass through channels
tight junctions in animals. creates an impenetrable barrier that prevents leakage
gap junctions in animals. forms connections for small molecules to pass through channels
desmosomes in animals. forms anchoring connections supporting cells under stress
endosymbiotic theory mitochondria and chloroplasts evolved from free-living prokaryotic cells
double both chloroplasts and mitochondria have a ___ membrane, circular DNA, cell membranes, and reproduce independently
membrane enfolding hypothesis proposes that the internal membrane systems found in eukaryotic cells originated from the plasma membrane of an ancestral prokaryotic cell folding inwards
lynn margulis proposed the endosymbiotic theory