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HSOC 400 Exam

Medicine in History: Comprehensive Notes

Before Hippocrates and Ancient Greek Medicine

Hippocrates (460-377 B.C.)

  • Author of Airs, Waters, and Places

  • Embraced observation as a key principle

  • Theory of the four humors (blood, phlegm, yellow bile, black bile) first appears in the Hippocratic treatise On The Nature of Man

  • Valued prognosis highly

  • Paid attention to a patient's habits, their environment (where they lived), and their temperament

  • Believed treatments must be tailored to the individual patient

Humoral Medicine

  • The appeal of humoralism, which dominated classical medicine and formed its heritage, lay in its comprehensive explanatory scheme

  • Drew upon bold archetypal contrasts (hot/cold, wet/dry)

  • Hippocrates adhered to this view (NOT the supernatural)

  • Extremely enduring concept that lasted for centuries

Galen

  • Took parts of the Hippocratic corpus and molded it together, adding his own thoughts

  • Prided himself on his knowledge

  • His knowledge was based on animal dissections because dissections [of humans] at the time were taboo

  • Gained knowledge of the body through dissection [of animals]

  • Followed the Hippocratic ideal that most medical cases are self-limiting

  • Adhered to the idea that patients valued prognosis and reassurance

  • In dissection, Galen was looking for anatomical rationality

  • According to Galen, the body was intelligible because it was created by a rational Creator

  • Other scholars and physicians readily viewed Galen as credible, and few doubted his claims about the human body for over a thousand years

Islamic Golden Age of Medicine

Avicenna, Ibn Sina (980?-1037)

  • In the Islamic world, the works of Galen, Hippocrates, and Aristotle were being read, discussed, translated, and taught to scholars and physicians

  • There was a flourishing of knowledge about medicine in the Islamic world at this time

  • Avicenna (Ibn Sina)

  • Focused on breaking things down to their fundamental basics/truths and then applying reasoning, like Galen and Aristotle

  • Author of The Canon of Medicine

    • Consisted of 5 parts

    • Translated into different languages

    • Brought together theories and practices of Greek medicine

Maimonides (c. 1137-1204)

  • Rabbi, philosopher, and physician

  • Born in Spain

  • Based upon his writings, scholars have surmised that Maimonides had profound knowledge of ancient Greek authors and Muslim writers

  • He was influenced by Muslim physicians and trained in traditional Jewish texts

  • Made recommendations about times for eating, amounts and types of food to be consumed, exercise, sleep habits, cathartics, climate and weather effects on eating habits, detrimental and beneficial foods, bathing, and bloodletting

  • Stressed PREVENTION rather than TREATMENT

Ibn Ridwan

  • Ibn Ridwan and other Islamic doctors embraced a naturalistic view of health and sickness

  • Much of his work was translated into Latin, Hebrew, and Turkish and made its way into the libraries of Venice and Istanbul

  • Based much of his knowledge on Galen; frequently challenged peers who dared to question Galen

  • Excluded the supernatural or spiritual as causative factors

  • Ibn Ridwan said that doctors have to understand the temperament of Egypt to treat people, which is similar to Hippocrates in Airs, Waters, and Places

  • Similarities exist between his work On the Prevention of Bodily Ills in Egypt and Hippocrates' Airs, Waters, and Places

Dissection in Medieval Islam

Dissection Practices

  • Scholarly works on legal rules about dissection in Medieval Islam are relatively small

  • It is likely that, from a legalistic viewpoint, human post-mortem dissection was not an impossibility within the medieval Islamic world

  • There appears to have been no actual explicit prohibition in Islam against dissection or post-mortem examination

  • The matter would have been left to jurists using legal reasoning to determine its appropriateness

  • There are certainly references to dissection in the writings of medieval Islamic physicians (references to dissections of apes, etc.)

  • There is little to suggest offense at the practice in the texts

William Harvey (1578-1657)

  • Performed vivisections on dogs

  • Calculated how many times the heart beats in an hour and estimated the heart's capacity

  • Used experimental ligation (tying off the blood flow)

  • A pioneer in physiology; he championed the idea that blood circulates throughout the body through the action of the heart

  • Published De Motu Cordis (1628)

  • Advocated to "search and study out the secrets of nature by way of experiment"

  • Proved that the heart does not "make blood"

  • Demonstrated there are no pores between the right and left side of the heart in which blood flows (a belief Galen put forth and which remained relatively unchallenged until Harvey's treatise)

Chinese Medical Practices

Traditional Practices

  • Bloodletting does happen (appears to be a decline in the practice in the Han dynasty)

  • Moxibustion (burning of mugwort—an herb—close to the skin)

    • Still used today for a variety of complaints, chronic pain, and even issues in pregnancy

  • Cupping

  • Acupuncture

Similarities and Divergences with Greek Medicine

  • Both appreciated that food was the source of blood

  • Both were concerned by the concept of plethora (or excess); "Shi" roughly translates to this concept of fullness

  • Both understood the need to prevent plethora or "shi"

Chinese Medical Knowledge

  • Myth that Chinese medicine was less concerned with anatomical structure—this is not true

  • Chinese medicine relied on pharmacological knowledge

  • Used numbing medicines (including aconite) and other toxic plants when setting bones and draining abscesses, and to numb injured flesh before surgeries

  • Reference: toxic medicinal plants from Li Shizhen (1518-93), Compendium of Materia Medica, Edition 1690

Bloodletting in the Medieval Era

Two Kinds of Bloodletting

  1. Periodic bloodletting: Those who were devoted to a life of religion might engage in this practice. This is typically a symbolic religious practice (found in monasteries)

  2. Prophylactic bloodletting: More common, this was more of a medical preventative (to preserve the body)

Instruments and Methods

  • Use of a lancet or fleam

  • Cupping (both wet and dry)

  • In wet cupping, dry cupping was followed by the forming of several incisions in the skin and a reapplication of the cups to collect blood

Dissection and Anatomy (1300-1600)

Attitudes About Dissection in Italy

  • Evidence from legal practice and medical training in cities of northern and central Italy shows that autopsy and dissection were not infrequent

  • First recorded case in Italy of a human body being opened for inspection dates from 1286

  • In Bologna, doctors might be called to open bodies in trials related to dubious deaths

  • These are cases of postmortems—procedures carried out on a corpse to gain information about the physical state of a particular body

Evolution of Dissection Practices

  • Between 1300 and 1600, dissection grew less taboo

  • Attention to the details, contours, and accuracies of the external human body emerged in art and other forms of cultural production

  • There was not a blanket ban on dissection from religious authorities per se

  • Taboos around dissection were more social, cultural, and regional, and less religious

  • In Italy, dissection was adopted more frequently due to beliefs that once a person died, the soul left the body—complete separation

  • In Northern Europe, the opposite view prevailed: there was an idea that the body still had some vestiges of the person

16th Century Dissection Practices

  • Dissections in the 16th century could be carried out in public or private

Before Vesalius: Three People Involved in Carrying Out Dissection for Anatomical Teaching

  1. Professor: Monitored progress and explained commentaries and texts

  2. Demonstrator: Letting people see what the professor explained

  3. Surgeon or Barber: Prepared the corpse and performed the cutting

Andreas Vesalius and Human Anatomy

De Humani Corporis Fabrica (On the Fabric of the Human Body)

  • This is Vesalius's great work

  • Vesalius performed his own dissections but also worked with artists to depict the human body with startling accuracy

  • Before Fabrica, Vesalius produced works that still conformed to Galen's notions of the human body (5 lobes in the liver!)

  • FYI: the human liver has 4 lobes!

The Bubonic Plague

Impact of the Plague

  • The 2nd pandemic is estimated to have wiped out 1/3 of Europe's population—the "BLACK DEATH"

  • Best estimates now are that at least 25 million people died in Europe from 1347 to 1352

  • Was almost 40% of the population (some estimates indicate 60%)

Understanding Plague

  • The idea that "miasmas" or foul air were a trigger to disease; created an epidemic constitution of the atmosphere

  • Poisoning of the atmosphere from the earth, decaying organic matter, miasma (or foul airs), poisonous emanations arising from swamps, etc., interacting negatively with humors as one possible cause of plague

  • Religious rationales were also blended in as well as celestial explanations

Symptoms and Progression

  • Bite from a flea

  • Then nausea/vomiting; flu-like symptoms

  • Bacteria multiply and invade lymph nodes, destroying the lymph system in the body

  • Buboes form in neck, armpits, groin, etc.

  • Buboes are extremely painful, emit a powerful stench

  • Powerful toxin is released into the blood vessels

  • Causes coma, neurological damage, dehumanizes and disfigures its victims

Historical Sources

  • Our knowledge about Bubonic Plague and societal impact is based on primary sources

  • Sources include accounts of the Black Death in Italy

  • Later iterations of the Bubonic plague are documented, including accounts from Samuel Pepys

  • Pepys is noted for his extensive and detailed diary which provided first-hand accounts of the Great Plague of London (1665-1666) and the Great Fire of London (1666)

Inoculation and Vaccination

Inoculation

  • Entailed taking pus collected from a pustule of a smallpox sufferer and placing it under the skin of a healthy individual to create a local infection and a mild form of the disease—thereby conferring life-long immunity against what might otherwise be a virulent and fatal case

  • The procedure was invasive and painful

Edward Jenner - English Physician

  • Noted for systematically testing the practice of vaccination—a new preventative measure that protected people against smallpox

Edward Jenner and Vaccination

  • In May 1796, Jenner encountered Sarah Nelms, a dairymaid with fresh cowpox lesions on her hands and arms

  • Jenner used matter from Nelms' lesions to inoculate an 8-year-old pauper, James Phipps

  • Phipps fell ill, but it was mild. He recovered

  • In July 1796, Jenner inoculated the boy again, this time with matter from a fresh smallpox lesion. No disease developed

  • This careful experimentation plus the already circulating hypothesis that people who recently had cowpox could not get smallpox, led to Jenner's discovery

  • This took him roughly 25 years to unravel

  • This use of cowpox (vaccinia) to protect against smallpox becomes the basis of vaccination

Race and Medicine in 19th Century America

The Myth of Innate Black Immunity to Yellow Fever

  • Notable figures: Richard Allen (portrait from 1823) and Benjamin Rush (portrait from 1814)

Dr. Samuel G. Morton

  • Philadelphia physician and founder of the "American School of Ethnology"

  • Published widely read works on craniometry (the study of brain size/intellect based on skull capacity)

  • Works include Crania Americana (1839) and Crania Aegyptiaca (1844)

  • His works reaffirmed pre-existing convictions that African-Americans, as well as other non-Caucasians, were inferior races

  • Trafficked in anti-Blackness

  • "Secret" polygenist who believed smaller skull size meant less intelligence

  • Morton received his 1st MD from University of Pennsylvania and 2nd MD from University of Edinburgh

Samuel A. Cartwright (1793-1863) - (Pro)Slavery Medicine

  • Prominent Louisiana physician with polygenesis leanings

  • Advanced the concept of "proslavery medicine"

  • Aimed to use medicine to justify slavery

  • Coined slave "diseases" including:

    • "Rascality" or Dysaesthesia aethiopica

    • "Drapetomania"—the disease which causes slaves to run away

  • Categorized these as mental illnesses

Important Concept: Clinical Racial Gaze

  • Willoughby: Clinical Racial Gaze is a combination of mastery of anatomy and the ability to "see" clinically with the cultural/social gaze which diminished Black people's humanity; largely due to slavery

Theories of Race by the 19th Century Two major schools of thought emerged regarding race:

  1. Polygenesis - distinct origins of humans. Each race evolved separately. Josiah C. Nott, for example

  2. Monogenesis - common origin of all human races (Traditional Biblical view of human race). Benjamin Rush, James Cowles Prichard, for example

In the antebellum era, both views trafficked in anti-Blackness.

Josiah C. Nott and Types of Mankind

  • Types of Mankind (1854) by Josiah C. Nott and George R. Gliddon argued that Black people formed a separate species, midway between whites and chimpanzees (Separate origins from whites)

  • Nott and Jeffries Wyman frequently compared Black people to animals

  • Nott had clear-cut anti-Black, proslavery medical views

  • Legitimized polygenesis, even if it was unorthodox

  • Types of Mankind was popular in the North!

Americans in Paris (and at Home)

  • American medical students with means traveled to Paris, France, spending time in clinics and hospitals for hands-on medical training

  • Upon their return, these students incorporated what they had learned in their practices and transmitted this knowledge in the domestic medical arena

  • Hands-on learning in the United States often meant "learning on" Black people's bodies

Joseph M. Leidy - M.D. 1844 (from Penn)

  • Professor of anatomy 1853-1891

  • His anatomy text (1861) was used for generations

  • Founder and head of Department of Biology 1885-1891

  • Believed the alleged anatomical differences between the races were small but significant

  • Different enough for separate taxonomy, but not different surgical technique

  • Leidy believed an anatomist could learn about both general human anatomy and the specific anatomy of Black people

Medical Education and Slavery African Americans (free and enslaved):

  • Were subject to abuse, experimentation, and neglect at the hands of physicians

  • They made up a population that was both visible and invisible

  • Their bodies were disproportionately used as anatomical teaching material

  • Their graves were more likely to be disturbed by body snatchers

  • They had no legal recourse to sue or stop medical schools from preying upon their bodies

Foucault's Clinical Gaze

  • "Clinical gaze": how the doctor views the patient is dependent upon the senses—seeing and hearing

  • The "gaze" dehumanizes and objectifies the patient

  • The disease is understood through what is going on internally in the patient and correlates with visible symptoms that are legible on the human body

  • Medical authority and patient submission is precisely the totalizing relationship of the clinical gaze as determined by Foucault in The Birth of the Clinic

  • The "clinical gaze" allows the physician to see what is hidden in the patient

  • Willoughby: Clinical Racial Gaze is a combination of mastery of anatomy and the ability to "see" clinically with the cultural/social gaze which diminished Black people's humanity; largely due to slavery

Infamous Cases of Grave Robbing

  • Burke and Hare were the two Scottish grave robbers or "resurrection men" who supplied the University of Edinburgh's medical school in the 19th century

  • They were encouraged by Robert Knox, who taught anatomy at the University of Edinburgh

  • Both men began to supply cadavers via murdering people rather than just stealing dead bodies

Specimens, Teaching Race and Anatomy

  • Education in anatomy relied on stolen skulls from around the world (Warren Anatomical Museum at Harvard)

  • Readily relied on accounts of victims of human trafficking ("Aztec Children" from El Salvador with microcephaly)

  • The children Bartola and Maximo were exhibited by P.T. Barnum (they were purchased from their mother and sold)

  • They were discussed as examples of "indigenous degeneracy"

  • Unclear if they were physically exhibited at Harvard during lectures, but their case was used to teach medical students


Summary: The Acceptance of Dissection Across Different Time Periods

The practice of human dissection experienced dramatically different levels of acceptance across cultures and time periods, shaped by religious, social, and cultural factors rather than uniform prohibitions.

Ancient Greece and Rome (Galen's Era)

During Galen's time, human dissection was taboo. As a result, Galen's extensive anatomical knowledge was based entirely on animal dissections. This limitation meant that some of his conclusions about human anatomy were incorrect (such as his claim that the human liver has 5 lobes, when it actually has 4). Despite these errors from working with animal subjects, Galen's authority remained largely unchallenged for over a thousand years.

Medieval Islamic World (10th-15th centuries)

In the medieval Islamic world, dissection occupied an ambiguous legal space. There was no explicit prohibition in Islam against dissection or post-mortem examination. The matter was left to jurists who used legal reasoning to determine appropriateness on a case-by-case basis. Medieval Islamic physicians wrote about dissection practices (including dissections of apes), and texts suggest little offense at the practice. From a legalistic viewpoint, human post-mortem dissection was not an impossibility, though scholarly works on the legal rules remain relatively small.

Medieval and Renaissance Italy (1286-1600)

Italy showed progressive acceptance of dissection. The first recorded case of a human body being opened for inspection dates to 1286. Evidence from legal practice and medical training in northern and central Italian cities shows that autopsy and dissection were not infrequent. In Bologna, doctors were called to open bodies in trials related to dubious deaths. Between 1300 and 1600, dissection grew less taboo, and there was not a blanket ban from religious authorities.

The acceptance in Italy was facilitated by the belief that once a person died, the soul left the body completely, allowing for separation between the spiritual and physical. This theological perspective made dissection more socially acceptable. Artists and physicians worked together, leading to increased attention to anatomical accuracy in both medical and artistic contexts.

16th Century Dissection Practices

By the 16th century, dissections had become formalized educational events. Dissections could be carried out in public or private settings. Before Vesalius revolutionized the practice, dissections for anatomical teaching involved three distinct roles:

  1. The Professor - monitored progress and explained commentaries and texts from above

  2. The Demonstrator - pointed out and displayed what the professor was explaining

  3. The Surgeon or Barber - prepared the corpse and performed the actual cutting

This hierarchical structure reflected the academic separation between theoretical knowledge (held by the professor) and manual labor (performed by the surgeon/barber). Vesalius notably broke with this tradition by performing his own dissections and working directly with artists to create accurate anatomical illustrations.

Northern Europe (1300-1600)

Northern Europe presented a stark contrast to Italy. Taboos around dissection were stronger due to the belief that the body still retained some vestiges of the person after death. This made dissection more culturally and socially problematic. The resistance was not primarily religious but rather rooted in cultural and regional attitudes about the relationship between body and soul after death.

19th Century Scotland

By the 19th century, the demand for cadavers for medical education at institutions like the University of Edinburgh had grown so intense that it created a black market. The infamous case of Burke and Hare—"resurrection men" who supplied cadavers first through grave robbing and then through murder—illustrates both the acceptance of dissection as essential to medical training and the ethical problems created by insufficient legal supply of bodies.

19th Century United States

In America, dissection was fully accepted as essential to medical education, but this acceptance came with deeply disturbing racial dimensions. While dissection itself was normalized, African Americans (both free and enslaved) were disproportionately used as anatomical teaching material. Their bodies were more likely to be stolen by body snatchers, they had no legal recourse to protect their bodies, and they were subject to abuse and experimentation. Medical students traveled to Paris for hands-on training, but in the United States, "hands-on learning" often meant "learning on Black people's bodies."

Conclusion

Dissection's acceptance evolved from completely taboo in ancient times (forcing Galen to rely on animals), to legally ambiguous but not explicitly prohibited (medieval Islamic world), to increasingly accepted for legal and medical purposes (Italy, 1286-1600), to formalized educational practice (16th century with structured roles), to essential but ethically problematic (19th century). The barriers were primarily social, cultural, and regional rather than uniformly religious. However, acceptance did not mean ethical practice—particularly in 19th century America, where dissection became entangled with slavery, racism, and the exploitation of Black bodies for medical education.