Depressive Disorder & Anxiety & Obsessive-Compulsive Disorders

Depressive Disorder

Objectives of Depression

  • Identify symptoms of various depressive disorders:

    • Disruptive Mood Dysregulation Disorder

    • Persistent Depressive Disorder (Dysthymia)

    • Premenstrual Dysphoric Disorder

  • Discuss the epidemiology of Major Depressive Disorder

  • Discuss biological and cognitive risk factors for the development of Major Depressive Disorder

  • Discuss treatment options including medication

  • Discuss nursing interventions related to depressive disorders

Disruptive Mood Dysregulation Disorder

  • Diagnosed in children ages 6 to 18

  • Symptoms:

    • Constant and severe irritability and anger

    • Temper tantrums that are out of proportion to the situation occurring at least 3 times per week

    • Exhibits symptoms in at least two settings (e.g., home, school, with peers)

  • Management strategies:

    • Symptomatic medications

    • Cognitive Behavioral Therapy (CBT)

    • Parent training

Persistent Depressive Disorder (Dysthymia)

  • Formerly known as Dysthymia

  • Characterized by low-level depressive feelings present throughout most of each day for the majority of days

  • Duration:

    • At least 2 years in adults

    • At least 1 year in children and adolescents

  • Must have two or more of the following symptoms:

    • Decreased appetite or overeating

    • Insomnia or hypersomnia

    • Low energy

    • Poor self-esteem

    • Difficulty thinking

    • Feelings of hopelessness

Other Depressive Disorders

Substance-Induced Depressive Disorder

  • Characterized by the absence of depressive symptoms when not experiencing drug or alcohol use or withdrawal.

Depressive Disorder Associated With Another Medical Condition

  • Examples include:

    • Cerebrovascular Accident (CVA)

    • Parkinson's Disease

    • Huntington's Disease

    • Alzheimer's Disease

    • Traumatic Brain Injury (TBI)

    • Cushing's Disease

    • Hypothyroidism

    • Arthritis

    • Back Pain

    • Metabolic Conditions

    • HIV

    • Diabetes

    • Infections

    • Cancer

    • Autoimmune Issues

Premenstrual Dysphoric Disorder

  • A symptom cluster appearing in the last week prior to the onset of a woman’s menstrual period, including:

    • Mood swings

    • Irritability

    • Depression

    • Anxiety

    • Feeling overwhelmed

    • Difficulty concentrating

  • Symptoms significantly decrease or disappear with the onset of menstruation

Major Depressive Disorder

  • Diagnosis requires the presence of five (or more) of the following symptoms in a 2-week period:

    • Weight and appetite changes

    • Sleep disturbances

    • Fatigue

    • Feelings of worthlessness or guilt

    • Loss of ability to concentrate

    • Recurrent thoughts of death

    • Psychomotor agitation

  • Additionally, at least one symptom must be either:

    • Depressed mood

    • Loss of interest or pleasure (anhedonia)

  • Duration:

    • Persistent for a minimum of 2 weeks to 6 months

    • Chronic: Lasting more than 2 years

    • Recurrent episodes are common

  • Symptoms must cause distress or impaired functioning

  • Episode cannot be attributed to physiological effects

  • Must have an absence of manic or hypomanic episodes

Treatment of Major Depressive Disorder

Medication Options

  • First-line therapy: Selective Serotonin Reuptake Inhibitors (SSRIs)

    • Rare risk of serotonin syndrome

    • Most common SSRIs:

    • Sertraline (Zoloft)

    • Paroxetine (Paxil)

    • Escitalopram (Lexapro)

    • Citalopram (Celexa)

  • Serotonin Norepinephrine Reuptake Inhibitors (SNRIs)

    • SSRIs may be better tolerated

    • Most common SNRIs:

    • Venlafaxine (Effexor)

    • Duloxetine (Cymbalta)

  • Tricyclic Antidepressants:

    • Associated with anticholinergic adverse reactions

  • Monoamine Oxidase Inhibitors (MAOIs)

    • Particularly effective for unconventional depression

Nursing Interventions for Depressive Disorders

  • Assess for patient safety

  • Focus on the patient’s strengths

  • Promote self-care and self-esteem

  • Assist with individual, family, and/or group therapy

  • Treatment goals to be mutually developed based on patient’s personal needs and values

Objectives of Anxiety Disorders

  • Define anxiety and its risk factors

  • Discuss different levels of anxiety

  • Identify defense mechanisms relevant to anxiety

  • Discuss clinical manifestations of various anxiety disorders:

    • Separation Anxiety Disorder

    • Specific Phobia

    • Social Anxiety Disorder

    • Panic Disorder

    • Agoraphobia

    • Generalized Anxiety Disorder

  • Identify risk factors contributing to anxiety disorders

  • Identify nursing interventions for anxiety disorders

  • Discuss treatment options including medications

Generalized Anxiety

  • Anxiety is characterized by apprehension, uneasiness, uncertainty, or dread from real or perceived threats

  • Fear is a reaction specifically to danger

  • Normal anxiety is essential for survival

  • Possible causes of anxiety include:

    • Genetic factors

    • Biological factors

    • Psychological factors

    • Cultural influences

Levels of Anxiety

  • Mild Anxiety

  • Moderate Anxiety

  • Severe Anxiety

  • Panic Anxiety

Case Study 1

  • Scenario: Anita, 34, experiences anxiety when shopping and realizes her child is missing.

  • Query: What level of anxiety would this likely result in?

    • Options:

    • Mild

    • Moderate

    • Severe

    • Panic

Defense Mechanisms Against Anxiety

  • Defense mechanisms are automatic coping styles that protect individuals from anxiety and maintain self-image by blocking feelings, conflicts, and memories.

  • Types of defense mechanisms:

    • Adaptive

    • Maladaptive

Other Anxiety Disorders

Separation Anxiety Disorder

  • Characterized by developmentally inappropriate levels of concern over being away from a significant other

Specific Phobias

  • Defined as a persistent irrational fear of a specific object, activity, or situation leading to avoidance behavior

Social Anxiety Disorder

  • Involves severe anxiety or fear provoked by exposure to social or performance situations that may be negatively evaluated by others

Panic Disorder

  • Defined by panic attacks characterized by an abrupt surge of intense fear or discomfort reaching a peak within minutes

Agoraphobia

  • Excessive anxiety or fear regarding places or situations from which escape may be difficult or embarrassing

Case Study 2

  • Scenario: Anita recalls struggles with panic disorder and her coping.

  • Query: What level of anxiety might be beneficial during a nursing exam?

    • Options:

    • Mild

    • Moderate

    • Severe

    • Panic

Treatment of Anxiety Disorders

Biological Approaches

  • Pharmacotherapy:

    • SSRIs and SNRIs

    • Antianxiety drugs

    • Other categories:

    • Beta blockers

    • Antihistamines

    • Anticonvulsants

    • Antipsychotics

  • Children & Adolescents:

    • Few drugs approved for children; Duloxetine/Cymbalta for ages 7-17; other medications prescribed off-label

Integrative Medicine

  • Herbal and dietary supplements

Behavioral Therapy

  • Techniques include:

    • Modeling

    • Systematic Desensitization

    • Flooding

    • Thought Stopping

    • Cognitive-Behavioral Therapy

Nursing Interventions for Anxiety Disorders

  • Stay with the patient when experiencing anxiety

  • Encourage patients to discuss their feelings

  • Reduce environmental stimuli

  • Teach relaxation techniques such as:

    • Progressive Muscle Relaxation

    • Guided Imagery

    • Deep Breathing

  • Make appropriate referrals as needed

Obsessive-Compulsive Disorder (OCD)

Symptoms

  • Cleaning: Fears of contamination leading to excessive cleaning rituals

  • Symmetry: Obsessions with symmetry that result in repeating, ordering, or counting actions

  • Characterized by repetitive thoughts that cause stress and repetitive behaviors demonstrating a perceived need for perfection

Treatment of OCD

Pharmacologic Therapy

  • SSRIs are commonly used for treatment

  • Deep Brain Stimulation (DBS) is an option for severe cases

Psychological Therapy

  • Various therapy options are available; specifics were not detailed in the provided transcript

Nursing Interventions for OCD

  • Assess for patient safety

  • Maintain a nonjudgmental attitude

  • Allow the patient time to perform ritualistic behaviors

  • Set reasonable limits

  • Encourage active diversions and coping skills

  • Assist in identifying progress and setting realistic expectations

Knowledge Check

  • Priority assessment question for major depression symptoms:

    • “Tell me about any special powers you believe you have.”

    • “You look really sad. Have you ever thought of harming yourself?”

    • “Your family says you never stop. How much sleep do you get?”

    • “Do you ever find that you don’t remember where you’ve been or what you’ve done?”