Units 1-5
Unit 1 - Nomenclature & Directional Terms
1. Anatomical Nomenclature & Directional Terms
Anatomical Nomenclature: A precise, universal language for describing the location, orientation, and relationships of body structures.
Ensures consistency regardless of an animal's position (standing, lying down).
Essential for clear communication in clinical and surgical settings.
Anatomical Planes of Reference
Imaginary flat surfaces used to conceptually divide the body into parts.
Four primary anatomical planes:
Median Plane (Midsagittal): Runs lengthwise down the center, dividing the body into equal left and right halves.
Sagittal Plane: Any plane parallel to the median, dividing the body into unequal left and right parts.
Transverse Plane: Crosswise and perpendicular to the long axis, dividing the body into cranial (front) and caudal (rear) segments.
Dorsal Plane (Frontal in humans): Horizontally runs in a standing animal, dividing it into dorsal (back) and ventral (belly) parts.
Human vs. Veterinary Terminology
Human Anatomical Terms are different from veterinary terminology:
Dorsal → Posterior
Ventral → Anterior
Cranial → Superior
Caudal → Inferior
Directional Terms
Directional terms are described in pairs of opposites to indicate relative positions:
Dorsal: Toward the back or spine (e.g., saddle on a horse’s dorsal surface).
Ventral: Toward the belly (e.g., cinch wraps around ventral surface).
Cranial: Towards the head (e.g., shoulder is cranial to the hip).
Caudal: Towards the tail (e.g., tail is caudal to the head).
Rostral: Toward the tip of the nose (only on the head, e.g., eyes are rostral to ears).
Medial: Toward the median plane (inner surface).
Lateral: Away from the median plane (outer surface).
Proximal: Closer to the body (used for limbs, e.g., proximal end of the femur).
Distal: Farther from the body (e.g., toes at distal end of leg).
Superficial: Toward the body surface (e.g., skin is superficial to muscle).
Deep (Internal): Away from the surface, toward the center (e.g., bone is deep to muscle).
Special Terminology for Limbs
Important to note that limb terminology changes based on location:
Forelimb:
From carpus (wrist) distally: Dorsal surface at the front, palmar surface at the back.
Proximal to carpus: Front is cranial, back is caudal.
Hind limb:
From tarsus (ankle) distally: Dorsal surface at the front, plantar surface at the back.
Proximal to tarsus: Cranial and caudal terms apply again.
Ventral: The term is never used to describe any part of the legs.
Common Regional Terms
Provide shorthand for describing areas, especially in large animals:
Barrel: The trunk formed by the ribcage and abdomen.
Brisket: Area at the base of the neck, between front legs.
Cannon: Large metacarpal or metatarsal bone in hoofed animals.
Fetlock: Joint between the cannon bone and proximal phalanx.
Flank: Lateral abdomen between the last rib and hind leg.
Hock: The tarsus.
Knee: The carpus in hoofed animals.
Muzzle: Rostral part of the face.
Poll: Top of the head between ears.
Stifle: Equivalent to human knee.
Withers: Area dorsal to the scapulas.
Movement Terminology
Describes changes in joint angles:
Flexion: Decreases angle between two bones (bending).
Extension: Increases angle between two bones (straightening).
Abduction: Movement away from the median plane.
Adduction: Movement toward the median plane.
Hyperflexion: Beyond normal flexion range.
Hyperextension: Beyond normal extension range.
2. Body Organization & Cavities
The organization of the animal body is hierarchical, from simplest to most complex structures.
Levels of Organization
Begins with Cells, the smallest living functional units (e.g., red blood cell).
Groups of specialized cells form Tissues:
Epithelial tissue: Covers body surfaces, lines cavities, forms glands (functions include protection, secretion, absorption).
Connective tissue: Supports and connects body parts (includes bone, cartilage, fat, and blood).
Muscle tissue: Responsible for movement (includes skeletal, cardiac, smooth).
Nervous tissue: Transmits electrical impulses for communication and control.
Multiple organs working together form Systems (e.g., digestive system).
Body Cavities
Spaces within the body that house and protect internal organs:
Dorsal Body Cavity: Subdivided into:
Cranial Cavity: Contains the brain.
Spinal Cavity: Contains the spinal cord.
Ventral Body Cavity: Larger and divided by diaphragm muscle into:
Thoracic Cavity: Contains heart and lungs.
Abdominal Cavity: Contains digestive, urinary, and reproductive organs.
Pelvic Cavity: Caudal end containing reproductive and excretory structures.
Cavities are lined by thin protective membranes:
Pleura: Lines thoracic cavity and covers lungs (visceral and parietal layers).
Peritoneum: Performs the same function in the abdominal cavity.
Inflammation of these membranes (pleuritis or peritonitis) can be extremely painful and serious.
Bilateral Symmetry
The animal body exhibits Bilateral Symmetry, meaning left and right halves are approximately mirror images.
Reflects in paired structures like lungs and kidneys, while single structures like heart and gastrointestinal tract are located on or near to the median plane.
3. Cells & Homeostasis
Cellular Basis of Life
Cells: Fundamental units of life.
Specialized cells perform specific tasks (e.g., intestinal cells specialize in absorption; red blood cells specialize in oxygen transport).
Osmosis, Diffusion, and Tonicity
Important concepts regarding fluid balance:
Osmosis: Movement of water across a semipermeable membrane.
Diffusion: Movement of solutes from high to low concentration.
Tonicity: The concentration of solutes in solutions relative to a cell's interior affects water movement.
Types of Solutions
Isotonic Solution: Same solute concentration as the cell, no net water movement (used during routine surgery to maintain hydration).
Hypertonic Solution: Higher solute concentration than the cell, causes water to leave the cell (used in severe hypoglycemia).
Hypotonic Solution: Lower solute concentration, causes water to enter the cell (used to help kidneys excrete excess fluids).
Homeostasis
Definition: Maintenance of a dynamic equilibrium despite changing external conditions.
Continuous monitoring and adjustment of vital parameters (body temperature, blood pH, oxygen levels, fluid balance).
Example: Congestive Heart Failure (CHF)
When the heart weakens, compensatory mechanisms activate (e.g., sympathetic nervous system increases heart rate, constricts vessels).
This can create a vicious cycle that worsens the condition, illustrating that homeostasis cannot always correct underlying issues.
Key Concepts
Cellular Communication: Essential for maintaining function and homeostasis.
Cellular Adaptability: Cells can respond to environmental changes, demonstrating homeostatic control.
4. Clinical & Study Applications
Radiography Positioning Terminology
Derived from anatomical directional terms; Radiographs (X-rays) named based on X-ray beam path.
Examples:
Ventro-Dorsal (VD) view: Beam enters ventral surface, exits dorsal.
Dorso-Palmar (DP) view: Enters dorsal, exits palmar surface.
Lateral view: Named for the side closest to the film (e.g., right lateral abdominal view).
Unit 2 - Cells
I. Cell Anatomy: Structure and Organelles
The cell is the fundamental unit of life, with a diversity of cell types correlating to their specific functions (e.g., disc-shaped red blood cells, long nerve cells).
Essential Structural Components
All mammalian cells consist of:
Cell Membrane: A dynamic, flexible barrier separating internal and external environments.
Cytoplasm: Contains the cytosol, cytoskeleton, and organelles.
Nucleus: Contains genetic material (DNA) controlling cell processes.
Cell Membrane (Plasma Membrane)
Fluid Mosaic Model:
Composed of a phospholipid bilayer with hydrophilic (water-loving) heads facing outward and hydrophobic (water-fearing) tails facing inward.
Proteins: Integral (span entire membrane) and peripheral (attach to surface).
Special Features:
Glycocalyx: Sugar coating for cell recognition, adhesion, and immune response.
Membrane Receptors: Bind external signaling molecules, triggering internal changes.
Caveolae: Invaginations involved in endocytosis and transcytosis.
Cytoplasm and Its Components
Cytoplasm: Includes:
Cytosol: Viscous fluid containing water, ions, ATP, proteins, and nutrients.
Cytoskeleton: Provides structure, shape, and movement with three types of fibers:
Microtubules: Hollow tubes for transport and cell division.
Intermediate Filaments: Durable support (e.g., keratin).
Microfilaments: Involved in membrane changes and muscle contraction.
Organelles (functionally specialized structures):
Mitochondria: Powerhouses that produce ATP through cellular respiration.
Ribosomes: Sites of protein synthesis, either free or attached to rough ER.
Endoplasmic Reticulum (ER):
Rough ER: Produces, modifies proteins.
Smooth ER: Synthesizes lipids, detoxifies substances.
Golgi Apparatus: Processes and packages proteins and lipids for delivery.
Lysosomes: Digests unwanted materials (cell's garbage disposal).
Peroxisomes: Detoxifies substances and neutralizes free radicals.
Proteasomes: Degrade misfolded proteins.
Centrosome: Organizes microtubules and helps during cell division.
Nucleus: The Control Center
Largest organelle, commands cellular activities, especially protein synthesis.
Structure:
Nuclear Envelope: Double lipid bilayer with pores for molecule transport (e.g., mRNA out).
Chromatin: DNA and histone complex that forms chromosomes during cell division.
Nucleolus: Synthesizes ribosomal RNA (rRNA) and assembles ribosomal subunits.
II. Cell Physiology: Function and Processes
Body Fluids and Homeostasis
Water: Approximately 60% of animal body weight, distributed into Fluid Compartments:
Intracellular Fluid (ICF): Inside cells, about 2/3 of total body water.
Extracellular Fluid (ECF): Outside cells, about 1/3 of total body water, subdivided into:
Interstitial Fluid: Between cells.
Intravascular Fluid: Within blood and lymph (plasma and lymph).
Electrolytes & Osmolality
Body fluids contain solutes; charged particles are electrolytes (e.g., Na⁺, K⁺, Cl⁻).
Osmolality: Total solute concentration, regulated by hormones (e.g., ADH which regulates kidney water reabsorption).
Fluid Movement & Edema
Edema: Abnormal fluid accumulation in interstitial spaces, often resulting from low plasma proteins.
Fluid Therapy: Essential for treating dehydration and electrolyte imbalances:
Crystalloids: Solutions with small electrolytes for rehydration.
Colloids: Larger molecules that remain in blood vessels to increase oncotic pressure during shock.
Membrane Transport: How Things Get In and Out
Selectively Permeable Membrane: Allows certain substances to enter or exit a cell.
Passive Processes (no ATP required):
Simple Diffusion: Movement down a concentration gradient.
Facilitated Diffusion: Needs carrier proteins for larger or polar molecules.
Osmosis: Diffusion specifically for water.
Filtration: Driven by hydrostatic pressure (e.g., blood pressure).
Active Processes (requires ATP):
Active Transport: Moves substances against their gradient (e.g., Sodium-Potassium Pump).
Cytosis: Transportation of large particles:
Endocytosis: Material engulfment.
Exocytosis: Expelling contents.
The Cell Life Cycle and Protein Synthesis
DNA Replication occurs during the S phase of Interphase, forming identical sister chromatids.
Mitosis: Division of the nucleus resulting in two identical daughter cells:
Prophase: Chromatin condenses into visible chromosomes.
Metaphase: Chromosomes line up at the cell's equator.
Anaphase: Chromatids separate and move to opposite poles.
Telophase & Cytokinesis: Nuclear envelope reforms, cytoplasm splits.
Protein Synthesis (Central Dogma): DNA → mRNA → Protein
Transcription: Occurs in nucleus to build mRNA from DNA template.
Translation: Ribosome uses mRNA to synthesize proteins with tRNA carrying specific amino acids.
Key Cellular Concepts
Resting Membrane Potential: Electrical charge difference across membranes, crucial for excitability in nerves and muscles.
Genetic Mutations: Errors in DNA that can cause disease.
Cell Differentiation: Process where unspecialized cells develop into specialized types.
Cancer: Uncontrolled cell division due to mutation in proto-oncogenes or tumor suppressor genes.
Membrane Transport Processes | Passive | Active |
|---|---|---|
No ATP | Crystal diffusion, facilitated diffusion, osmosis, filtration | Na⁺/K⁺ pump, endocytosis, exocytosis |
Effects of Tonicity on Red Blood Cells | Hypotonic | Isotonic | Hypertonic |
|---|---|---|---|
Swell/Burst | Normal Shape | Shrink/Crenate |
Transcription vs. Translation | Location | Process | Key Player |
|---|---|---|---|
Nucleus | DNA → mRNA | RNA polymerase | |
Cytoplasm | mRNA → Protein | Ribosome, tRNA, amino acids |
Unit 3 - Tissues
I. INTRODUCTION TO TISSUES
Unicellular vs. Multicellular Organisms:
Unicellular: Independently surviving (e.g., paramecium).
Multicellular: Specialized and interdependent cells forming tissues.
II. FOUR PRIMARY TISSUE TYPES
Epithelial – Covers and lines structures.
Connective – Supports and binds other tissues.
Muscle – Enables movement.
Nervous – Controls and communicates.
III. TISSUE ORGANIZATION
Tissues → Organs → Organ Systems.
Most organs comprise all four tissue types (e.g., heart).
IV. GROSS vs. MICROSCOPIC ANATOMY
Gross Anatomy: Visible structures to the naked eye.
Microscopic Anatomy (Histology): Study of tissues and cells under a microscope.
V. EPITHELIAL TISSUE
General Functions
Protection and covering, filtration, absorption, sensory input, secretion, and excretion.
General Characteristics
Polarity: Apical (free) vs. basal (attached) surfaces.
Cellular Attachments: Tight junctions, desmosomes, gap junctions.
Avascular: Lacks blood vessels, relies on diffusion.
Innervated: Many have sensory nerve endings.
Cellular Junctions
Tight Junctions: Seal adjacent cells (e.g., urinary bladder).
Desmosomes: Provide sturdy connections (e.g., skin).
Gap Junctions: Channels for communication (e.g., cardiac muscle).
Basement Membrane
Nonliving layer anchoring epithelium to underlying connective tissue, allowing diffusion.
Surface Specializations
Microvilli: Increase surface area for absorption (e.g., intestines).
Cilia: Move debris (e.g., trachea).
Keratin: Provides waterproofing (e.g., skin).
Classification of Epithelia
Based on layers and cell shape:
Simple (one layer) vs. Stratified (multiple layers).
Shapes: Squamous, cuboidal, columnar.
Surface specializations determine additional classification (ciliated, keratinized).
Types of Epithelia
Simple Squamous: Thin, for diffusion (e.g., alveoli).
Simple Cuboidal: Secretion/absorption (e.g., glands).
Simple Columnar: Absorption; may have goblet cells (e.g., intestines).
Stratified Squamous: Protect against abrasion (e.g., skin).
Stratified Cuboidal/Columnar: Rare; protective roles in ducts.
Pseudostratified: Appears layered but all touch basement membrane (e.g., trachea).
Transitional: Stretches (e.g., bladder).
VI. GLANDS
Definition
Cells that manufacture and discharge secretions.
Development
From invaginated epithelial sheets; may retain ducts (exocrine) or be ductless (endocrine).
Classification
Endocrine: Ductless; secrete directly into blood (e.g., hormones).
Exocrine: Retain ducts; secrete onto surfaces (e.g., sweat, salivary glands).
Unicellular: Goblet cells.
Multicellular: Classified by duct shape and secretion mode:
Merocrine: Exocytosis (e.g., pancreas).
Apocrine: A portion of the cell is lost (e.g., sweat glands).
Holocrine: Whole cell ruptures (e.g., sebaceous glands).
VII. CONNECTIVE TISSUE
General Characteristics
Most abundant tissue by weight, derived from mesoderm, and vascularized (except cartilage/tendons).
Composed of: cells, fibers, and ground substance (extracellular matrix).
Functions
Support, protection, insulation, energy storage, transportation, defense, and repair.
Components
Ground Substance: Gel-like, contains glycosaminoglycans (GAGs) like hyaluronic acid.
Fibers:
Collagen: Strong, white fibers (e.g., tendons).
Reticular: Supportive networks (e.g., lymph nodes).
Elastic: Stretchable (e.g., arteries).
Cells:
Fixed: Fibroblasts (produce fibers), adipocytes (fat cells), reticular cells.
Wandering: Leukocytes, mast cells, and macrophages are involved in defense.
Types of Connective Tissue
Connective Tissue Proper:
Loose Connective Tissue:
Areolar: Cushions organs.
Adipose: Stores fat.
Reticular: Supports lymphatic tissue.
Dense Connective Tissue:
Dense Regular: Parallel collagen (e.g., tendons).
Dense Irregular: Interwoven collagen (e.g., dermis).
Elastic: High elastic fiber content (e.g., arteries).
Specialized Connective Tissue:
Cartilage: Avascular and slow healing.
Hyaline: Most common (e.g., joints).
Elastic: Flexible (e.g., ears).
Fibrocartilage: Shock absorber (e.g., intervertebral discs).
Bone: Hard, vascular, stores calcium.
Blood: Fluid matrix (plasma) and cellular components (erythrocytes, leukocytes).
VIII. MEMBRANES
Definition
Thin layers of epithelial and connective tissue.
Types
Mucous Membranes: Line passages open to the outside; secrete mucus (e.g., digestive tract).
Serous Membranes: Line closed cavities, secretes serous fluid (e.g., pleura, peritoneum).
Cutaneous Membrane: Skin (epidermis + dermis).
Synovial Membrane: Lines joints; secretes synovial fluid, contains no epithelium.
IX. MUSCLE TISSUE
General Function
Facilitates contraction via actin and myosin mechanisms.
Types
Skeletal Muscle: Voluntary, striated, multinucleated.
Smooth Muscle: Involuntary, non-striated, spindle-shaped (located in walls of organs).
Cardiac Muscle: Involuntary, striated, branched, and contains intercalated discs.
X. NERVOUS TISSUE
Function
Transmits electrical and chemical signals.
Cell Types
Neurons: Conduct impulses (cell body, dendrites, axon).
Neuroglial Cells: Support, protect, and nourish neurons.
XI. TISSUE HEALING AND REPAIR
Inflammation
Signs include redness, heat, swelling, and pain, proceed via vasoconstriction to vasodilation, increased permeability, clot formation, and phagocytosis.
Organization
Formation of granulation tissue composed of collagen and capillaries to resist infection.
Regeneration/Fibrosis
Epithelialization: New epithelial layer forms; potential scarring occurs which can impair function.
Healing Classifications
First Intention: Minimal scarring with edges close together.
Second Intention: Granulation fills gaps with scarring present.
Factors Affecting Healing
Age, health, nutrition, infections, medications (e.g., corticosteroids).
XII. CLINICAL APPLICATIONS
Parvovirus: Destroys rapidly dividing epithelial cells.
Mucous Membrane Examination: Used to assess hydration, oxygenation, and circulation (capillary refill time).
Histopathology: Study of diseased tissues, critical for biopsy.
Adhesions: Abnormal fibrous connections after surgery/inflammation.
In-Depth Study Guide: The Skeletal System
I. INTRODUCTION TO THE SKELETAL SYSTEM
Functions of the Skeletal System
Support: Provides structural framework.
Protection: Shields vital organs (e.g., skull protects the brain).
Leverage: Acts as levers for muscle movement.
Storage: Reservoir for minerals (calcium, phosphorus).
Blood Cell Formation (Hematopoiesis): Occurs in red bone marrow.
Calcium Homeostasis: Regulated by calcitonin (deposits calcium) and parathyroid hormone (withdraws calcium).
II. BONE CHARACTERISTICS & STRUCTURE
Bone Composition
Cells:
Osteoblasts: Bone-forming cells.
Osteocytes: Mature bone cells trapped in lacunae.
Osteoclasts: Bone-resorbing cells.
Matrix: Collagen fibers + ground substance (polysaccharides) hardened by hydroxyapatite (calcium phosphate).
Canaliculi: Channels facilitating osteocyte communication.
Types of Bone
Compact Bone: Dense and strong, arranged in Haversian systems (osteons).
Cancellous (Spongy) Bone: Light and porous, containing trabeculae (spicules) filled with marrow.
Bone Membranes
Periosteum: Outer fibrous layer containing osteoblasts.
Endosteum: Lines the medullary cavity and contains osteoblasts.
III. BONE FORMATION & GROWTH
Mechanisms
Endochondral Ossification: Cartilage model replaced by bone, typical for most bones.
Intramembranous Ossification: Bone develops directly from fibrous membrane (forming flat bones of the skull).
Growth Plates (Epiphyseal Plates)
Cartilage plates between epiphysis and diaphysis; site for longitudinal bone growth, ossifying as growth stops.
IV. BONE SHAPES & EXAMPLES
Classification of Bone Shapes
Long Bones: Longer than wide, with a shaft (diaphysis) + two ends (epiphyses). (e.g., femur, humerus).
Short Bones: Cube-shaped, composed of spongy core (e.g., carpal bones).
Flat Bones: Thin and flat; layers of compact bone with spongy bone in between (e.g., scapula).
Irregular Bones: Complex shapes (e.g., vertebrae).
V. BONE FEATURES (MARKINGS)
Articular Surfaces
Condyle, Head, Facet: Smooth surfaces for articulation (e.g., distal femur for condyle).
Processes
Projects for muscle/tendon attachments (e.g., tuberosity).
Holes & Depressions
Foramen: Holes for nerves/vessels (e.g., obturator foramen).
VI. AXIAL SKELETON
Skull
Cranium (brain case): External bones include occipital, parietal, frontal; key features include foramen magnum and external acoustic meatus.
Ear Bones (Ossicles): Malleus, incus, stapes transmit sound vibrations.
Facial Bones: Include maxillary, mandible; key features include mandible structure and hard palate.
Hyoid Bone: Supports tongue, pharynx, larynx.
Vertebral Column: Composed of cervical, thoracic, lumbar, sacral, and coccygeal vertebrae.
VII. APPENDICULAR SKELETON
Thoracic Limb
Scapula: Shoulder blade, includes important landmarks like the glenoid cavity.
Humerus: Upper arm structure with distinct features.
Radius & Ulna: Provide forearm structure.
Carpal Bones: Arrangement of bones in the wrist.
Metacarpal Bones & Phalanges: Variations in bones based on species.
Pelvic Limb
Pelvis (Os Coxae): Components include ilium, ischium, and pubis.
Femur: Features like the head and femoral neck.
Patella: Largest sesamoid bone provides knee protection.
Tibia & Fibula: Important bones in the lower leg.
Tarsus & Metatarsals
Similar configuration to forelimb bones but with specific adaptations.
VIII. VISCERAL SKELETON
Includes bones that develop within soft organs (e.g., os cordis in cattle, os penis in dogs).
IX. JOINTS (ARTHROLOGY)
Joint Types
Fibrous Joints (Synarthroses): Immovable (e.g., skull sutures).
Cartilaginous Joints (Amphiarthroses): Slightly movable (e.g., intervertebral discs).
Synovial Joints (Diarthroses): Freely movable, most common.
Synovial Joint Structure
Characteristics include articular cartilage, joint capsule, ligaments,
Key example: Stifle joint, a complex joint subjected to injury (e.g., CCL rupture).
Movements at Synovial Joints
Includes flexion, extension, abduction, adduction, rotation, and circumduction.(e.g., elbow flexing).
X. CLINICAL APPLICATIONS
Bone Healing (Fracture Repair)
Repair requires realignment and immobilization; callus formation and remodeling can take months.
Common Disorders
Includes intervertebral disc disease, patellar luxation, and hip dysplasia.
Diagnostic Landmarks
Specific vertebrae used as landmarks; body condition scoring assesses fat distribution.
Detailed Study Guide on Joints
Introduction to Joints
Joints: Junctions between bones classified into three main types: immovable (fibrous), slightly movable (cartilaginous), and freely movable (synovial).
Types of Joints
Fibrous Joints (Synarthroses): Held by dense tissue; examples include skull sutures.
Cartilaginous Joints (Amphiarthroses): Allow slight movement; examples include intervertebral discs.
Synovial Joints (Diarthroses): Freely movable joints characterized by a joint cavity filled with synovial fluid, with notable examples including shoulder and hip joints.
Structure of Synovial Joints
Components include smooth articular cartilage covering bone ends, joint capsule, synovial fluid, and ligaments for stability.
Key example: Stifle joint involves stability through ligaments (Cruciate, Patellar) and cartilage (menisci).
Clinical Application – Cranial Cruciate Ligament (CCL) Rupture
A common injury in dogs, often leading to stifle instability; diagnosed via palpation and imaging; treatment can involve rest or surgical repair.
Movements at Synovial Joints
Flexion, extension, abduction, adduction, rotation, and circumduction.
Classification of Synovial Joints by Shape and Movement
Categorized into:
Hinge Joints: Allow only flexion and extension (e.g., elbow).
Gliding Joints: Allow slight gliding (e.g., carpus).
Pivot Joints: Allow rotation (e.g., atlantoaxial joint).
Ball-and-Socket Joints: Allow wide range of motion (e.g., shoulder).
Visceral Skeleton
Includes special bones within soft organs, examples include os cordis (cattle) and os penis (dogs).