Midterm Review Unit 1-5

Unit 1

Water

water (H2O) - polar, O negative & H positive

  • traits affect its adhesion, cohesion, surface tension, high specific heat, low density when frozen, universal solvent

  • adhesion of the water to cell walls by hydrogen bonds helps resist the downward pull of gravity (ability to stick to the walls), cohesion due to hydrogen bonds between water molecules helps hold together the column of water within the cells (ability to attach to each other)

  • provides insulation for aquatic animals when the top surface of a body of water is frozen

Elements of Life

carbon, hydrogen, oxygen, nitrogen, sulfur, phosphorous

Carbon Chemistry

carbon - acts as the backbone for many molecules, can create 4 covalent bonds

isomers - break down into structural & geometric isomers

  • structural - differ in covalent partners

  • cis-trans isomers - differ in arrangement about a double bond

    • cis - the X groups are on the same side

    • trans - the X groups are on opposite sides

enantiomers - differ in spatial arrangement around an asymmetric carbon, resulting in molecules that are mirror images, like left and right hands

Structure and Properties of Macromolecules & Nucleic Acids

Creating Polymers

polymerization reactions - the creation of polymers

  • dehydration synthesis - removes a water molecule, forming a new bond, H2O as a byproduct

  • hydrolysis - adds a water molecule, breaking a bond

Carbohydrates

monomer - monosaccharides

polymer - polysaccharides

C6H12O6 - glucose

  • plant

    • starch - storage, alpha glucose monomers

    • cellulose - structural polysaccharides

  • animal

    • glycogen - storage, beta glucose monomers

Lipids

no monomers/polymers, do not elongate, nonpolar

fats/oils

  • glycerol molecule attached to three fatty acid chains

    • saturated - straight, no double bonds

    • unsaturated - bent, double bonds present

phospholipids

  • negative phosphate head - dissolve in water, hydrophillic

  • lipid tails - do not dissolve in water, hydrophobic

Proteins

monomers - amino acids

polymer - polypeptides, form peptide bonds in between amino acids

amino acid - R group differentiates each amino acid, folds the long strand into a 3-D structure

  • primary structure - sequence of amino acids

  • secondary structure - alpha helices or beta pleated sheets

  • tertiary structure - 3-D shape stabilized by interactions between side chains

  • quaternary structure - association of multiple polypeptides, forming a function protein

Nucleic Acids

monomer - nucleotides (sugar/deoxyribose, nitrogenous base, phosphate group)

DNA - ATCG, doesn’t have a second Oxygen, anti parallel double helix

RNA - GUAC, single stranded

Unit 2 Cell Structure and Function

plant cells - have cell wall, chloroplasts

animal cells -

Cell Membrane Structure

fluid mosaic model - phospholippids arent the only thing that made up the plasma membrane

integreated proteins

peripheral proteins

glycoproteins

glycolipids - unsaturated (enhance fluidity) v. saturated tails (packed tighter so more rigid)

cholesterol - inhibit the cells from being too fluid or too hard

does not let charged or polar things through membrane

channel proteins - closed or open

  • diffusion - high concentration to low

  • facilitated diffusion - allows a channel or carrier protein so it can move from high to low

  • active transport - low to high

    • pumps - uses ATP to drive the process

  • aquaporins - channel proteins specific to water

  • osmosis - watre moving to low to high solute concentration, moves water to the opposite direction of solutes if possible

    • will move to lower concentration

    • water moves to dilute something

      • hypotonic - lower solute concentration; water rushes into the cell leading to lyses or being turgid, cell wall can withstand pressure

      • isotonic - net movement of water being equal in and out

      • hypertonic - more solute on the outside; water is moving from the outside, shriveling the cell

eukaryotic cells - organelles, carry out multiple enyzymatic processes

Unit 3 Enzymes, Photosynthesis, Cell Respiration

enzymes - proteins that catalyst chemical reactions

  • has a structure that combines substrates and changes it to reduce the energy required to go under chemical change

  • affected by environmental factors: pH, temperature—denaturation, salinity

allosteric regulation - enzymes turned on or off

photosynthesis - energy from sunlight harnessed to produce glucose

  • plants absorb lights from pigment chlorophyll, can make electrons excited by using photons from the sunlight (blues and reds, transmitting green)

photosystems - harnesses energy of exciting electrons to pump hydrogen ions or protons from stroma into the thylakoids, creating a concentration gradient

  • electron cn only leave from atp synthase, relieving the gradient by creating atp

photosystem I - electrons passed onto an electron acceptor called NADPH

loss of electrons replenished by water

atp and nadph prodced by light reactions i sused in calvin cycle

calvin cycle -

  • three cycles

    • carbon fization - rubp and c molecule combined trhough enxyme rubisco which forms a 6 crbon molcule which splits into 3 pg

    • reduction - reduced by nadph

    • regeneration - made into rubp

cell respiration - process of breaking down sugar

1 glycolygsis

— glucose is brone into two halfs, called pyruvates, need to invest atp

— netgain of 2 atp

2 pyruvvate oxidation

— pyruvate put in mitochondria and loses co2

electrons released so frmation of nadh molecule

  1. krebs cycle

2 6 carbon acid releases wo co2

releases 6 nadh, 2 fadh2, 4 atp

  1. oxidative phosporylation

electrons removed by o2, final e- acceptor which is joined by 2 h atoms to form water

atp is formed

Unit 4

3 main steps to cell signal

  1. reception - signaling molecule attaches to receptor, knocking the gtp

  2. tranduction - gtp moves

  3. response - gtp hits cellular response/activated enzyme

cell cycle

interphase

  • g1 - dna rows

  • s - dpublicate dna

  • g2 - prepare for mitotic phase

mitotic phase

  • prophase - condensation of dna, spindle fibers form to segreegate chromosomes

  • metaphase - chromosomes lined up in a line

  • anaphase - chromatids separate

  • telophase & telokinesis - chromosomes recondense and separate

Unit 5 Hereditary

meisosis

diploid - paired chromosome set

23 chromosomes from each gamete, 46 chromosomes in a person

gametes - haploid, one half of genetic blah

meiosis 1

  • prophase 1 - nuclear envelope disintegrating, spindle fibers, etc., hoomologous chromosomes pair up creating corssing voer, making hybrid chromatids comibing mom and dads dna

  • metaphase 1 - paired chromosomes align randomly, some with dads chromosomes on top or botom and same with mom

  • anaphose 1 - homologous pairs seprating

meisosis 2

  • anaphase 2 - sister chromatids separating

mendelian genetics

gene - region of dna that encodes a part or whole of a protein, codes a particular charaacter

diploid organisms have two copies of each gene

alleles - variants of genes

dominance - some alleles can mask or overshadow another allele

phenotype - an orgnaisms phsyicall genes expression

genotype - how we symboli represent an organisms genetic components

homozygous dominant

heterozygous

homozzygous recessive

AAxaa

P0 cross

AaxAa

F1 cross

Test cross

Aaxaa

dihhybride = AaBb, 9;3:3:1

9 - dominant traits 3 - has dominant traits but other is recessive, 1 recessive for both

law of segregration - an individuals with 2 alleles will only pass one of two allels into the next generation

law of dominance - certain genes can comppltely mask the recessive alleles

law of independent assortment - produces 4 possible combination with equal probabiblity

non mendelian genetics

incomplete dominance - two alleles that don’t react but rather show a blend

co-dominance - penetrance of both alleles

epistatis - one gene affects the expression of another gene

polygenic inheritance - mutiples genes affect a isngle trait ex. height, skin tone

genes and environment factors -

pedigrees -

  • autosomal recessive -

  • automial dominanatn

  • x linked

  • mitochondrial