Medical gases are crucial in healthcare, particularly in oxygen therapy and anesthetics.
This chapter focuses on the storage and delivery systems for medical gases, emphasizing practical understanding.
Laboratory Gases: Used for calibrating equipment and diagnostic testing.
Example: Used in pulmonary function tests to check machine accuracy.
Therapeutic Gases: Aimed at relieving symptoms and improving patient oxygenation, especially for hypoxemia.
Anesthetic Gases: Provided with oxygen for anesthesia during surgeries.
Properties: Colorless, odorless, tasteless, transparent.
Density at STP: 1.429 grams/liter (slightly heavier than air).
Solubility: Minimal in water with only 3.3 mL of oxygen dissolving in 100 mL at room temperature (not crucial to memorize).
Combustion: Non-flammable but accelerates combustion; must keep flammable materials away.
Chemical Methods: Produce small volumes; examples include electrolysis of water.
Fractional Distillation: Most common method; filters and liquefies atmospheric air, separates oxygen (21% in air) from nitrogen.
Physical Separation: Involves methods like molecular sieves and oxygen concentrators, the latter extracting oxygen from ambient air.
Comprised mainly of atmospheric air: approximately 21% oxygen and 78% nitrogen; has been filtered and compressed to remove pollutants.
Commonly used in devices like nebulizers that deliver filtered air for therapeutic use.
Carbon Dioxide (CO2): Used in calibration and laboratory tests, colorless and non-flammable but supports combustion; FDA purity standard is 99%.
Helium: Therapeutic for airway constriction due to its low density; needs to be mixed with oxygen for safety.
Nitric Oxide: Colorless, toxic gas used primarily as a pulmonary vasodilator, particularly for infants with hypoxic respiratory failure.
Nitrous Oxide: Commonly known as laughing gas; used as an anesthetic agent, requiring a mixture with oxygen at all times.
Gases are stored in gas cylinders made of seamless steel, regulated by the Department of Transportation.
Safety features include pressure relief valves to avoid explosive incidents from overheating or over-pressurization.
Charging (Filling) Cylinders: Involves specific techniques; most often done by dedicated services, especially in hospital settings.
The gas duration can be estimated using the formula:Duration(mins) = (Pressure (PSI) * Cylinder Factor) / Flow Rate (L/min)
For example, an E cylinder at 1,500 PSI at 5 L/min lasts 84 minutes.
Upper airway's role is to heat and humidify inspired air; loss of humidity occurs with artificial airways like ET tubes or trach.
Humidity Deficit: Infection and complications can occur due to inadequate humidity intake; supplemental humidity is required for patients bypassing the upper airway.
Active Humidifiers: Include bubble humidifiers, passover humidifiers, nebulizers, and vaporizers which add water and/or heat.
Passive Humidifiers: Heat Moisture Exchangers (HMEs) recycle exhaled moisture for added humidity when breathing in.
Temperature and Flow Rate: Higher temperature generates more humidity; however, high flow rates can reduce contact time leading to less humidity absorption.
Clinical Uses: To manage bronchospasm, intubation recovery, upper airway edema, and to induce sputum sample production.
Involves liquid particles suspended in gas; can include sterile saline for hydration or medicated solutions.
Used to manage airway edema, promote secretions, or assist in working with artificial airways.
Common devices include jet nebulizers or larger volume nebulizers, which adjust for adequate FiO2 levels while providing humidity.
Attention to potential complications like infections, overhydration, and airway irritation from excessive humidity or incorrect use of nebulizers.
Monitor settings and patient responses closely during aerosol therapy.
Understanding the properties, production, storage, and delivery of medical gases is critical in respiratory care.
Mastery of these concepts ensures effective treatment and promotes patient safety in diverse clinical scenarios.