Cell Theory

Page 8: History of Cell

  • Robert Hooke examined a piece of cork and found little structures in it which he compared to cellulae

    • These structures were named "cells"

    • Later discovered that the cells found in the cork were actually outer walls of former plant cells

  • Zacharias Janssen invented the microscope in 1608

  • Anton van Leeuwenhoek examined different subjects using a refined microscope and found moving protists and sperm, which he called "animalcules"

Page 13: The Cell Theory

  • The Cell Theory is one of the basic principles of biology

  • The three main principles of the Cell Theory are:

    1. The cell is the basic unit of life

    2. All living organisms are composed of cells

    3. New cells are created from pre-existing cells

Page 14: 1st Postulate: Cell is the basic unit of Life

  • In order for an organism to be considered living, it must have a cell

  • Movement of organelles inside a cell is proof that an organism is alive

Page 15: 1st Postulate: Cell is the basic unit of Life

  • In the cork examined by Hooke, the protoplasm of the cell had already dissipated, indicating the cell's death

  • Leeuwenhoek observed animalcules shooting and spinning inside the cells of his teeth scrapings

Page 16: 2nd Postulate: All living organisms are composed of cells

  • Matthias Jacob Schleiden established that plant specimens are composed of cells

  • Theodore Schwann discovered that animals are also composed of cells

Page 17: 3rd Postulate: New Cells are created from preexisting cells

  • Rudolf Virchow introduced the third tenet of the cell theory: "Omnis cellula e cellula" which means "Cells come from pre-existing cells"

Page 19: Development of Cell Theory

  • Zacharias Janssen invented the objective microscope in 1590

  • Robert Hooke viewed a thin slice of cork with a primitive microscope in 1663-1665

  • Marcello Malpighi and Nehemiah Grew conducted separate investigations on plant cells and determined the presence of organelles within them

Page 21: Development of Cell Theory

  • Anton van Leeuwenhoek upgraded Janssen's microscope and discovered mobile organelles in many subjects, which he called animalcules

Page 22: Development of Cell Theory

  • Robert Brown discovered the nucleus in 1831

  • Matthias Schleiden recognized that plant parts come from cells and proposed that the different structures of a plant are all composed of cells

Page 24: Development of Cell Theory

  • Theodore Schwann declared that animals are likewise composed of cells, ending the debate about the structural origin and composition of plants and animals

  • Albrecht von Roelliker stated that sperm and egg are composed of cells and that all humans are configured from cells

  • Louis Pasteur proved that bacteria are able to multiply and that bacterial cells come from other bacterial cells

Page 26: Development of Cell Theory

  • Rudolf Virchow declared "Omnis cellula e cellula" which means "Cells come from pre-existing cells", completing the cell theory

Page 29: Microscopy: Foundation of Cell Theory

  • Microscopy started in the 14th century in Italy

  • Hans and Zacharias Janssen assembled an apparatus with two lenses in one tube

  • Anton Van Leeuwenhoek created the first compound microscope to observe varied specimens and learn more about cells

Page 33: Transmission Electron Microscope

  • In 1931, Ernest Ruska and Max Knoll invented the transmission electron microscope, which relied on electrons instead of light

Page 35: Phase Contrast Microscope

  • In 1932, Fritz Zernike developed the phase contrast microscope (PCM