AP Biology Unit 2 – Cells: Ultimate Study Notes (CED aligned)

Cell Structure

Prokaryotic vs Eukaryotic Cells

Cell Type Differences
  • Prokaryotes:

    • No nucleus

    • No membrane-bound organelles

    • Smaller and simpler

  • Eukaryotes:

    • Nucleus present

    • Membrane-bound organelles

    • Larger and more complex

  • Cause → Effect

    • Presence of organelles → increased efficiency and specialization

  • Tips

    • Always connect structure to function

    • If comparing → mention size + organelles

Organelles and Their Functions

Nucleus and Genetic Control
  • Contains DNA

  • Controls cell activities

Mitochondria and Energy
  • Site of cellular respiration

  • Produces ATP

Ribosomes and Protein Synthesis
  • Make proteins

  • Found free or attached to rough ER

Endoplasmic Reticulum
  • Rough ER: protein synthesis

  • Smooth ER: lipid synthesis and detoxification

Golgi Apparatus
  • Modifies and packages proteins

  • Cause → Effect

    • More mitochondria → more ATP production

    • Ribosome presence → increased protein production

  • Tips

    • If a cell is active → mention more mitochondria or ribosomes

Cell Membrane Structure

Phospholipid Bilayer

Membrane Structure
  • Made of phospholipids

  • Hydrophilic heads face outward

  • Hydrophobic tails face inward

Membrane Fluidity and Components

Fluid Mosaic Model
  • Membrane is flexible

  • Contains proteins, cholesterol, carbohydrates

  • Proteins:

    • Transport

    • Communication

  • Cholesterol:

    • Maintains fluidity

  • Cause → Effect

    • Unsaturated lipids → more fluid membrane

    • Cholesterol → stabilizes membrane

  • Tips

    • Use term: fluid mosaic model

    • Always mention hydrophobic/hydrophilic

Selective Permeability

What Can Cross
  • Small nonpolar molecules pass easily

  • Polar and large molecules need help (proteins)

  • Cause → Effect

    • Membrane structure → controls what enters/exits

  • Tips

    • Phrase: “selectively permeable membrane”

Membrane Transport (Heading 1)

Passive Transport

Diffusion and Facilitated Diffusion
  • Diffusion: movement from high → low concentration

  • Facilitated diffusion: uses transport proteins

  • No ATP required

Active Transport

Movement Against Gradient
  • Moves substances from low → high concentration

  • Requires ATP

  • Uses protein pumps

Osmosis and Tonicity

Water Movement
  • Water moves from high → low water potential

Tonicity Effects
  • Hypertonic:

    • Higher solute outside

    • Cell shrinks

  • Hypotonic:

    • Lower solute outside

    • Cell swells

  • Isotonic:

    • No net movement

  • Cause → Effect

    • Solute concentration → water movement → cell size change

  • Tips

    • “HIPPO”:

      • Hypo = water goes in

    • Always mention water potential or gradient

Surface Area and Cell Size

Surface Area to Volume Ratio

Importance
  • Small cells = higher surface area to volume ratio

  • Allows faster exchange of materials

  • Cause → Effect

    • Increased SA:V → more efficient transport

    • Large cells → slower exchange → need adaptations

  • Tips

    • If question mentions size → talk about SA:V ratio

Cell Size Adaptations

Structural Adaptations
  • Folding (microvilli) increases surface area

  • Long or thin shapes improve exchange

Compartmentalization

Membrane-Bound Organelles

Function of Compartments
  • Separate cellular processes

  • Increase efficiency

  • Prevent interference between reactions

  • Cause → Effect

    • Compartmentalization → specialization → efficiency

  • Tips

    • Big idea: division of labor in the cell