chapter 12

Chapter 12: Respiratory System

Physiology of Respiration

  • External Respiration

    • The exchange of air in the lungs and between capillaries:

    • Process: Oxygen is inhaled into the air sacs of the lungs, where it is approximately 21% O2.

    • Gas Exchange: Oxygen immediately passes into the capillaries, while carbon dioxide passes from the capillaries into the air sacs to be exhaled.

    • Composition of Exhaled Air: Exhaled air contains about 16% O2.

  • Internal Respiration

    • The exchange of gases at the cellular level:

    • Occurs simultaneously between cells and capillaries.

    • Oxygen Movement: Oxygen passes out of the bloodstream (from capillaries) into the tissues.

    • Carbon Dioxide Movement: Carbon dioxide moves from the tissues back into the bloodstream to travel to the lungs.

Anatomy of the Respiratory System

  • Mediastinum

    • Defined as the middle part of the chest.

    • Where the trachea divides into two bronchi.

    • The space is located outside and between the two lungs.

  • Hilum of the Lung

    • Contains:

    • Blood vessels

    • Nerves

    • Lymphatic tissues

    • Bronchial tubes (entering and exiting the lung)

  • Lungs Anatomy

    • Lobes Structure:

    • Right Lung: Larger with 3 lobes.

    • Left Lung: Smaller with 2 lobes.

  • Bronchi

    • Bifurcate from the trachea, leading to each lung.

  • Bronchioles

    • Smaller branches that end in the alveoli.

  • Alveolus

    • Site of gas exchange.

Respiratory Flow Chart

  • Sequence of conducting air:

    • Nose (nares)

    • Nasal cavities and paranasal sinuses

    • Pharynx:

    • Includes Adenoids and Tonsils

    • Larynx

    • Epiglottis

    • Trachea

    • Bronchi

    • Bronchioles

    • Alveoli

    • Lung Capillaries

Vascular and Lung Circulation

  • Cava

    • Meaning "hollow".

    • Pulmonary Artery: Carries O2-poor blood from the heart to the lungs.

    • Pulmonary Vein: Carries O2-rich blood from the lungs to the heart.

  • Vena Cava: Comprises left vein and is referred to as hollow.

Key Structures of the Respiratory System

  • Nasal Cavity

  • Laryngopharynx

  • Larynx

  • Mediastinum

  • Pleura: Parietal and Visceral layers

  • Lung

  • Diaphragm

  • Terminal Bronchiole

  • Pulmonary Vessels

  • Alveoli: including aerial ducts

Respiratory Pathologies

  • Epistaxis:

    • Common bleeding from the nose, noticed when blood drains through the nostrils.

  • Asthma:

    • Characterized by reversible airflow obstruction and bronchospasm. Thought to stem from genetic and environmental factors.

  • Bronchiectasis:

    • Involves permanent enlargement (dilation) of airway parts. Bronchi become dilated, inflamed, and easily collapse. Can arise from conditions like pneumonia, tuberculosis, or cystic fibrosis.

  • Emphysema:

    • Characterized by hyperinflation of alveoli due to loss of elasticity.

    • Involves narrowed small airways and breakdown of lung tissue.

  • Chronic Obstructive Pulmonary Disease (COPD):

    • Encompasses conditions leading to long-term breathing issues and poor airflow, with shortness of breath and productive cough as major symptoms.

  • Lung Cancer:

    • Malignant growth characterized by uncontrolled cell growth in lung tissues.

    • Symptoms include coughing (possibly with blood), weight loss, shortness of breath, and chest pains.

  • Pneumonia:

    • Inflammatory condition primarily affecting alveoli, typically caused by viral or bacterial infection. Symptoms include cough, fever, and chest pain.

  • Pulmonary Embolism:

    • Occurs when a blood clot travels to the lungs, blocking major blood vessels and causing difficulty in breathing and chest pain.

Clinical Procedures

  • CPAP (Continuous Positive Airway Pressure):

    • A method of applying mild air pressure to open airways, often used in premature infants and for sleep apnea treatment.

  • Bronchoscopy:

    • Involves the insertion of a flexible endoscope into bronchial tubes for viewing, diagnosis, or biopsy purposes.

  • Endotracheal Intubation:

    • Placement of a tube from mouth to trachea to secure airway.

  • Thoracentesis:

    • Surgical puncture to remove excess fluid from the pleural space.

  • Tracheostomy:

    • A surgical procedure creating an opening through the neck into the trachea for secure airway access and secretion drainage.

  • Spirometry:

    • Common pulmonary function test measuring lung abilities in terms of air volume and speed during inhalation and exhalation.

Important Abbreviations in Respiratory Medicine

  • COPD: Chronic Obstructive Pulmonary Disease

  • DVT: Deep Vein Thrombosis

  • PE: Pulmonary Embolism

Vocabulary

  • Adenoids: Lymphatic tissue in the nasopharynx.

  • Alveoli: Air sacs in the lungs responsible for gas exchange.

  • Carbon Dioxide (CO2): Waste gas produced by body cells; exhaled via the lungs.

  • Diaphragm: Muscle below the lungs aiding in breathing, separating the chest from the abdomen.

  • Epiglottis: Lid-like cartilage covering the larynx.

  • Parietal Pleura: Outer fold of pleura lying closer to the chest wall.

  • Visceral Pleura: Inner fold of pleura neighboring lung tissue.

Combining Forms and Terminology

  • adenoid/o: adenoids

  • alveol/o: alveolus, air sac

  • bronch/o: bronchial tube

  • bronchi/o: bronchus

  • bronchiol/o: bronchiole

  • capn/o: carbon dioxide

  • spi/o: to breathe