Hypersensitivity - Active recall questions

  1. define hypersensitivity

  2. what is it often called

  3. when does it occur

  4. what do all immune reactions result in

  5. what is an allergen

  6. where can this be a concern clinically?

  7. what does von Pirquet say about allergies

  8. what does the term allergy refer to now

  1. what are the two types of hypersensitivity

  2. describe the first type

  3. what is the first type further subdivided into

  4. what are each of these further types

  5. describe the second type

  6. what is a further category of this second type

  1. what is type 1 hypersensitivity

  2. what is the antigen

  3. what is the mediator

  4. what is the skin test with antigen (intradermal)

  5. max reaction

  6. histology

  1. what are mast cells

  2. role of mast cells

  3. what happens when a mast cell is activated

  4. how can mast cells be stimulated to degranulate

  5. what do mast cells have a high affinity for

  6. describe their affinity to this product

  7. describe what happens in allergic reactions in relation to mast cells

  1. what is the relevance of histamine

  2. what does it cause

  3. what does this result in

  4. what does histamine irritate

  5. what are cutaneous signs of histamine release

  1. what is type 2

  2. what does it occur in

  3. antigen

  4. mediator

  5. histology

  1. what is type III

  2. may be…?

  3. antigen

  4. mediator

  5. skin test with antigen (intradermal)

  6. max reaction

  7. histology

  1. what is type IV

  2. what does it occur in

  3. antigen

  4. mediator

  5. skin test with antigen

  6. max reaction

  7. histology

  1. what is anaphylaxis

  2. when does it occur

  3. what are the likely causes of anaphylaxis

  4. symptoms of anaphylaxis

  5. what can this progress to

  6. signs?

  7. management of anaphylaxis

  8. what are the adrenaline doses

  9. chair position to manage anaphylaxis

  10. what to monitor

summarise the 4 different types of hypersensitivity