Biology, Behavior, Mind — Neurons, Structure, and Neural Signaling

Localization of Function

  • The brain is organized such that various regions have particular functions (localization of function).

  • Biological psychology studies the links between biology (genetic, neural, hormonal factors) and psychological processes.

  • The mind/brain are involved in processing and constructing experiences through integrated information across brain systems.

  • Our adaptive brain is wired by experience, meaning learning and environment shape neural connections and functions.

  • Examples in everyday experience include how brain systems process sensory experiences like color; information is integrated to form coherent perceptions.

Neurons: Structure and Function

  • Neurons are the basic building blocks of the nervous system.

  • A neuron is a cell body with branching fibers.

  • Dendrites: bushy, branching extensions that receive messages from other neurons; they listen to incoming signals.

  • Axons: long extensions that pass messages to other neurons, muscles, or glands; they speak by sending signals away from the cell body.

  • Dendrites listen; axons speak.

  • Some axons are long; dendrites are often shorter.

The Neuron: Dendrites, Axons, and Communication

  • Dendrites receive information via their branches.

  • Axons transmit information to other neurons, muscles, or glands.

  • The basic communication pattern is from dendrites to the cell body, then along the axon to the terminal endings.

Myelin and Conduction

  • Myelin sheath: a fatty layer segmentally encasing the axon.

  • Myelinated axons enable vastly faster transmission of neural impulses.

  • Conduction occurs more quickly because the impulse hops from node to node along the axon (saltatory conduction).

  • The presence of myelin increases neural efficiency, supporting faster judgment and control.

  • Degeneration of myelin can lead to Multiple Sclerosis, which disrupts neural communication and can cause loss of muscle control.

  • Nodes of Ranvier are the gaps between myelin segments where the impulse jumps.

Axons, Nodes, and Impulse Transmission

  • Axons carry messages away from the cell body toward other neurons, muscles, or glands.

  • The axon membrane contains a selective barrier that regulates which ions can cross, influencing electrical transmission.

Resting Potential and Ion Exchange (Cellular Basis)

  • The neuron’s resting potential is established by ions distributed inside and outside the axon.

  • Outside the axon: positively charged ions; inside the axon: negatively charged ions.

  • The interior of the axon is negatively charged relative to the exterior during resting potential.

  • The axon's surface is selectively permeable, allowing certain ions to pass while restricting others.

Action Potential: The Neural Impulse

  • When a neuron fires, a neural impulse travels down the axon as an action potential.

  • During this process, ions are exchanged across the membrane.

  • Sodium ions (Na+) flow into the membrane, contributing to depolarization.

  • The refractory period is the period of inactivity after a neuron has fired.

  • During recovery, sodium ions are pumped back out (and other ions are redistributed) to restore the resting state.

  • Positive ions outside and negative ions inside help drive the electrical change across the membrane.

Excitatory vs Inhibitory Signals; Threshold

  • Signals can be excitatory (pushing toward firing) or inhibitory (pushing toward stopping).

  • The threshold is the level of stimulation required to trigger an action potential.

  • If excitatory signals exceed inhibitory signals, an action potential is triggered; otherwise, the neuron does not fire.

  • This creates a discrete all-or-none response: a neuron fires fully or not at all.

  • The rate of firing (frequency) conveys information about stimulus intensity, within the constraints of neuronal mechanisms.

All-or-None Principle and Firing Rate

  • Action potentials are all-or-none; a neuron either fires a full impulse or none.

  • When firing occurs, the frequency of action potentials can encode the strength or intensity of the stimulus.

Clinical and Practical Implications

  • Myelin integrity is crucial for rapid and reliable neural communication; demyelinating diseases (e.g., Multiple Sclerosis) impair muscle control and other functions.

  • Understanding synaptic transmission and action potentials underpins medical treatments that affect neural signaling (pharmacology, neuroprosthetics, rehabilitation).

  • The brain’s plasticity (its ability to rewire in response to experience) has practical implications for education, therapy, and recovery after injury.