Cell theory
Cell Theory
Principles of Cell Theory:
All living organisms are composed of one or more cells.
Cells are the smallest units of life.
New cells arise only from pre-existing cells through cell division.
Organization of Animal Bodies
All animal cells share similarities in:
Material exchange with surroundings.
Energy acquisition from organic nutrients.
Synthesis of complex molecules.
Reproduction.
Response to signals.
Animals begin life as a single fertilized egg, which divides and specializes into various cell types.
Cell Characteristics and Proteomes
Proteome: Different proteins expressed determine the characteristics of various cell types, despite identical DNA in each cell.
Cell Morphology
Eukaryotic cells exhibit significant variation in size and shape, even within cells having the same genome.
Types of Animal Tissue
There are four general types:
Epithelial Tissue: Forms continuous sheets to cover/line surfaces.
Connective Tissue: Supports and connects tissues.
Nervous Tissue: Conducts electrical signals.
Muscle Tissue: Facilitates movement.
Epithelial Tissues
Function: Cover organs, line cavities, protect and absorb.
Types based on layers:
Simple: Single layer.
Stratified: Multiple layers.
Pseudostratified: Appears stratified but is one layer.
Cell Shapes: Cuboidal, squamous, and columnar.
Connective Tissues
Functions include:
Connecting and supporting structures.
Comprising blood, adipose, bone, and more.
Formulating an extracellular matrix (ECM).
Types of ECM Proteins: Collagen and elastin (for strength and flexibility).
Blood Composition
Blood consists of red and white blood cells and platelets within plasma containing electrolytes and proteins.
Adipose tissue provides insulation and energy storage.
Nervous Tissue
Comprises complex networks of neurons that conduct electrical signals.
Functions include initiating and conducting impulses affecting muscles and glands.
Muscle Tissue
Specialized for contraction:
Types:
Skeletal Muscle: Voluntary movement.
Smooth Muscle: Involuntary control of tubes.
Cardiac Muscle: Involuntary, found in the heart.
Tissues and Organ Systems
Tissues: Groups of similar cells, over 200 types in humans.
Organs: Combinations of tissues performing specific functions.
Organ Systems: Collections of organs working together (e.g., digestive, nervous systems).
Homeostasis
Definition: Maintenance of stable internal conditions despite external changes.
Regulators: Actively maintain internal conditions, using more energy.
Conformers: Match internal environment with external, using less energy.
Homeostatic Variables
Variables like blood glucose levels fluctuate but are regulated by mechanisms ensuring stability.
Examples include temperature regulation, blood sugar, and pressure regulation.
Homeostatic Control Systems
Components of control include:
Set Point: Normal value.
Sensor: Monitors the variable.
Integrator: Compares sensor input with set point.
Effector: Initiates response to restore set point.
Feedback Mechanisms
Negative Feedback: Reduces output or activity to maintain the set point (e.g., temperature control).
Positive Feedback: Amplifies changes in a process until completion (e.g., childbirth, blood clotting).
Feedforward Regulation
Prepares the body for changes before they occur, optimizing responses and minimizing deviations.
Key Cell Processes
Six basic processes:
Cell division
Growth
Differentiation
Migration
Apoptosis
Cell connections
Body Fluids
Composed mainly of water.
Compartmentalized into intracellular (inside cells) and extracellular (outside cells) fluids.
Types of Extracellular Fluids: Plasma (blood) and interstitial fluid (between cells).
Cell Communication
Essential for coordinated activities within organisms.
Types of signaling include:
Direct intercellular signaling
Contact-dependent signaling
Autocrine signaling
Paracrine signaling
Endocrine signaling.
Stages of Cell Signaling
Three stages:
Receptor activation
Signal transduction
Cellular response.
Ligands bind to receptors affecting cellular processes.
Example of Signaling Pathway
Epinephrine: A fight-or-flight hormone influencing various body functions.
Involves a cascade of reactions leading to changes in cellular activity, such as increased heart rate.