Neural Communication, Neuroplasticity, and Brain Damage
Neurotransmitters
- Different types of neurotransmitters exist, with endorphins being a popular category.
- Endorphins are commonly referred to as morphine within, focusing on pain control and pleasure/rewarding behavior.
- Neurotransmitters affect brain processes like emotions and stability.
- Charts in textbooks and notes provide information on various neurotransmitters.
- The focus is on neurotransmitters that occur naturally in the brain and body.
Key Neurotransmitters and Their Functions
- Acetylcholine: Memory, attention
- Dopamine & Serotonin: Pleasure, arousal, reward
- Norepinephrine & Acetylcholine: Alertness (on switches)
- GABA: Downer, turns things off
- Glutamate: Memory
- Endorphins: Pain and pleasure
Agonists and Antagonists
- Agonists: Increase the effect of neurotransmitters by mimicking receptor sites or making it easier for neurotransmitters to get in. They can mimic or block reuptake production.
- Antagonists: Block or inhibit neurotransmitters by blocking the receptor sites or stopping the reuptake process. They prevent neurons from releasing neurotransmitters, prolonging their effect.
How Drugs Work
- Drugs work by targeting receptor sites.
- Agonists mimic neurotransmitters, creating more of a sensation or making it easier for neurotransmitters to enter neurons.
- Antagonists block neurotransmitters or stop the reuptake process.
- Reuptake inhibitors prevent neurons from releasing neurotransmitters, prolonging their effect.
Painkillers
- Two main types of painkillers: Acetaminophen and Ibuprofen.
- Acetaminophen (e.g., Tylenol) reduces pain and fevers.
- Ibuprofen (e.g., Advil) reduces pain and inflammation.
- It's important to know which type to take depending on the issue.
- Tolerance for painkillers can develop with continued use, leading to addiction.
The Endocrine System
- The endocrine system involves hormones, which function similarly to neurotransmitters but affect organs instead of the brain.
- Hormones work slower than neurotransmitters.
- Hormones are created by endocrine glands and travel through the bloodstream.
- Some hormones are identical to neurotransmitters but take different routes.
- The adrenal and pituitary glands are important for hormone production within the autonomic nervous system.
Biopsychosocial Approach
- Biopsych involves biological factors, behavioral science, neuroscience, behavior genetics, and physiology.
- Psychology cannot be divorced from biology; they work together.
- The modern biopsychosocial approach integrates biological, psychological, and social factors.
- Brains are roughly the same size from person to person, though larger now than in cavemen.
- Each sub system must be integrated.
Neuroplasticity
- Neuroplasticity is the brain's ability to change and adapt.
- It is easier and faster in children, but adults can also reorganize and build new pathways.
- The brain is always changing and building new pathways as you learn.
- Neuroplasticity is what sets humans apart from animals, allowing for faster adaptation.
- The more you practice, the more you develop pathways
Lesions
- Lesions refer to tissue destruction, often in the brain in the context of psychology.
- The brain still wants to rewire after lesions, especially in childhood.
Brain Imaging Systems
- Different imaging systems are specialized for different things.
- EEG (Electroencephalogram): Reads activity as it goes through the brain, showing where neurons are active.
- MEG (Magnetoencephalography): Looks at magnetic fields from brain's neural activity.
- CT Scan (Computed Tomography): Takes x-rays from different angles to build an image of the brain.
- PET Scan (Positron Emission Tomography): Tracks activity by tracking glucose with a dye, showing where activity is happening.
- MRI (Magnetic Resonance Imaging): Uses radio waves to create a computer model of soft tissue.
- fMRI (functional MRI): Looks at natural blood flow to show brain activity and structural abnormalities.
Neurogenesis
- Neurogenesis is the ability to form new neurons as the brain learns and adapts.
- The brain has a limited ability to repair itself; it can rewire but not fully repair.
- Younger brains can reorganize more easily.
- Severely injured areas of the spine and brain cannot regenerate.
Split Brain Research
- The corpus callosum connects the left and right hemispheres, enabling communication.
- Split brain surgery separates the hemispheres, often to treat severe epilepsy.
- Cutting the corpus callosum doesn't affect personality because the lobes are still intact.
- The two sides of the brain are close together but not fused; the corpus callosum keeps them connected.
Split Brain Experiments
- In experiments, split-brain patients focus on a dot with words on either side. Normal brains perceive "heart," but split brains see "he" and "art" separately.
- Verbal responses come from the left side (e.g., saying "art"), while motor responses come from the right side (e.g., pointing to "he").
- The right side of the brain controls the left side of the body, specializing in facial recognition and spatial awareness.
- The left side of the brain controls the right side of the body, specializing in logic, math, and spatial reasoning.
- Each hemisphere has control of the opposite side of the body.
- Right side: facial recognition, spatial awareness, self-awareness.
- Left side: logical, mathematical, spatial reasoning.