Action Potential
All-or-nothing principle: A neuron fires at full strength or not at all.
Steps: Resting potential β Depolarization (Na+ influx) β Repolarization (K+ efflux) β Refractory period.
CNS vs. PNS
CNS (Central Nervous System): Brain and spinal cord (integration center).
PNS (Peripheral Nervous System): Nerves outside CNS (sensory/motor pathways).
Neurons
Most common type: Multipolar neuron (e.g., motor neurons).
Structure: Dendrites (receive signals), cell body, axon (transmits signals), myelin sheath (insulation).
Functional types: Sensory (afferent), motor (efferent), interneurons.
Reflex Arc
Example: Knee-jerk reflex.
Path: Receptor β Sensory neuron β Spinal cord β Motor neuron β Effector (muscle).
Senses
Vision:
Most acute vision: Fovea centralis (cones for color/detail).
Accommodation: Lens changes shape to focus light.
Disorders: Myopia (nearsightedness), hyperopia (farsightedness), cataracts.
Taste/Smell: Chemoreceptors detect chemicals (taste buds, olfactory epithelium).
Blood
Cell types:
Erythrocytes (RBCs: carry Oβ/COβ via hemoglobin).
Leukocytes (WBCs: immunity).
Platelets (clotting).
Plasma: Liquid portion (water, proteins, electrolytes).
Normal pH: 7.35β7.45 (slightly alkaline).
Blood Vessels
Arteries: Carry oxygenated blood away from heart (thick walls).
Veins: Return deoxygenated blood to heart (valves prevent backflow).
Capillaries: Site of gas/nutrient exchange (thin walls).
Heart
Path of blood: RA β RV β Lungs β LA β LV β Body.
Pacemaker: SA node (initiates heartbeat).
Heart sounds: "Lub-dub" (AV valves closing, then semilunar valves).
Layers: Pericardium (outer sac), myocardium (muscle), endocardium (lining).
Pulmonary Ventilation
Inspiration: Diaphragm contracts (volume β, pressure β).
Expiration: Diaphragm relaxes (volume β, pressure β).
Key Structures
Epiglottis: Covers trachea during swallowing.
Larynx: Voice box (vocal cords).
Pleural membrane: Reduces friction around lungs.
Lung Volumes
Tidal volume: Normal breath (~500 mL).
Vital capacity: Max inhalation/exhalation.
COβ Role: Regulates blood pH (converted to bicarbonate in blood).
Path of Food
Mouth β Esophagus β Stomach β Small intestine β Large intestine β Anus.
Key Organs
Liver: Produces bile, detoxifies blood.
Gallbladder: Stores bile.
Pancreas: Releases digestive enzymes (e.g., amylase, lipase) and insulin.
Absorption
Nutrients: Mostly in small intestine (villi increase surface area).
Teeth
Adult count: 32 teeth.
Structure: Enamel (hardest substance), dentin, pulp (nerves/vessels).
Terms
Bolus: Chewed food mixed with saliva.
Chyme: Partially digested food leaving stomach.