Mental Health and Aging Notes

Introduction

  • By 2030, approximately 20% of the U.S. population will be 65 or older.

  • Increase in older adults with mental health issues is expected.

  • Important to study psychopathology in late life within lifespan development.

  • Differentiate between early-onset disorders persisting into older adulthood and late-onset disorders.

  • Psychopathology may manifest differently over time (heterotypic continuity).

Normal Development in Late Life

  • Characterized by stability and change in biological, cognitive, social, and emotional domains.

  • Biological aging: changes in the central nervous system and increased risk of physical illness.

  • Fluid intelligence declines with age; crystallized intelligence remains stable or improves.

  • Social changes: bereavement, retirement, caregiving; most older adults remain independent.

  • Selective Optimization and Compensation Model: aging is associated with narrowing opportunities (selection), enhancing abilities (optimization), and using alternative methods (compensation).

  • Socioemotional Selectivity Theory: social goals shift from information-oriented to emotion-oriented in late life.

Anxiety

  • Relatively common in late life.

  • Lifetime prevalence of any anxiety disorder is approximately 14.9% in adults aged 65 and older.

  • Specific phobias and social phobias are most common.

  • DSM-5 changes: removal of requirement of awareness of excessive anxiety for diagnoses of specific phobia, social phobia, and agoraphobia.

Description and Course:
  • Older adults report less frequent negative emotions and physiological arousal.

  • They may use exact language (e.g., "concerned" instead of "worried").

  • Phobias, panic attacks often co-occur with physical illnesses.

  • Older adults with GAD are more likely to worry about health.

Etiology:
  • Varies by anxiety disorder; can be rooted in conditioning.

  • Biological, psychological, and social factors increase vulnerability.

Explanation for Age Differences:
  • Frequent comorbid medical and psychiatric conditions complicate diagnosis.

  • Providers may mistakenly attribute anxiety symptoms to normal aging.

  • Emotion regulation skills may improve with age.

Assessment and Treatment:
  • Assessment is challenging due to diagnostic complexities.

  • Geriatric Anxiety Inventory and Geriatric Anxiety Scale are available.

  • Antidepressants and cognitive behavioral interventions are effective treatments.

Mood Disorders

  • Depression is a common and consequential disorder in late life.

  • Mood disorders include major depressive disorder, persistent depressive disorder, and bipolar disorder.

  • Depressive symptoms that do not meet mood disorder criteria are frequent and associated with adverse outcomes.

  • Major depressive disorder: characterized by pervasive dysphoria or anhedonia for at least 2 weeks, accompanied by additional symptoms.

  • Diagnostic criteria changes in DSM-5: depression following bereavement is no longer excluded from diagnosis.

Etiology:
  • Involves interplay between biological, psychological, and social vulnerabilities and stressors.

  • Reduction in meaningful and rewarding activities may lead to depression.

Explanation for Age Differences:
  • Diagnostic rubrics may not fully capture depression as manifested in old age.

  • Older adults are less likely to endorse dysphoria or anhedonia.

Assessment and Treatment:
  • Depression is underdetected in late life.

  • Cognitive behavioral therapy, problem-solving therapy, and reminiscence therapy are effective interventions.

  • Internet-delivered cognitive behavioral therapy is equally acceptable and effective.

Suicide

  • Older adults, particularly older men, have elevated rates of death by suicide.

  • Suicidal behavior: suicidal ideation, suicide attempts, and death by suicide.

  • Suicidal acts in late life are more likely to be fatal.

Etiology:
  • Interpersonal theory of suicide: interaction between desire to die and acquired capability for suicide.

  • Risk factors include depression, poor social support, dysfunctional coping strategies, and neurocognitive deficits.

Assessment and Prevention:
  • Interventions to reduce suicide include physician education and cognitive-behavior therapy.

  • Programs using social connectedness and peer companions are being tested.

Schizophrenia

  • Lifespan neurodevelopmental disorder; prevalence is lower in older adults.

  • Diagnostic criteria: delusions, hallucinations, disorganized speech, grossly disorganized or catatonic behavior, or negative symptoms.

  • Leading theories attribute etiology to genetic or biological vulnerability combined with environmental stressors.

Explanation for Age Differences:
  • Lower prevalence in late life may result from remission of the disease or selective mortality.

  • Late-onset schizophrenia refers to onset after age 40, and very-late-onset schizophrenia-like psychosis refers to onset after age 60.

Assessment and Treatment:
  • Antipsychotic medications are effective in controlling positive symptoms.

  • Cognitive behavioral social skills training improves social functioning.

Alcohol Use Disorders

  • Less common in late life but associated with severe health consequences.

  • DSM-5 diagnosis requires meeting two of 11 criteria, resulting in significant distress or impairment.

  • Some older adults start problem drinking after age 50, often in response to age-related stressors.

Etiology:
  • Arise from interaction of genetic risk and environmental factors.

  • Risk factors include pain, chronic medical conditions, sleep difficulties, and depression.

Explanations for Age Differences:
  • Excessive drinking declines with age; physiological changes may contribute to increased sensitivity to alcohol.

  • Alternative explanation is selective mortality.

Assessment and Treatment:
  • Accurate assessment is critical; underdetection and underreporting occur in primary care settings.

  • Elder-specific treatments are especially beneficial.

Hoarding

  • Hoarding disorder: persistent difficulty discarding possessions, accumulation of possessions cluttering living spaces, and significant distress or impairment.

  • Onset typically during adolescence; the course appears to be progressive and chronic across the lifespan.

  • Older adults who are socially isolated, never married, and have a history of childhood trauma are often more likely to hoard.

Epidemiology:
  • Hoarding is relatively common during late life, with prevalence rates estimated between 2% and 5%.

  • Associated with medication and dietary mismanagement, impairments in daily living, and premature relocation to senior housing.

Etiology:
  • Conceptualized as a result of information-processing deficits, beliefs about and emotional attachment to possessions, and avoidance behaviors.

Assesment and Treatment:
  • Hoarding problems often go undetected and untreated among older adults.

  • A newly developed behavioral treatment for compulsive hoarding disorder in older adults shows promise.

Personality Disorders

  • Pervasive and inflexible patterns of behavior associated with distress or impairment.

  • Antisocial Personality Disorder (ASPD) and Borderline Personality Disorder (BPD) are less prevalent.

  • Schizoid Personality Disorder (SPD) and Obsessive-Compulsive Personality Disorder (OCPD) appear to be more prevalent.

Etiology:
  • Can be conceptualized as maladaptive and extreme variants of normal personality traits.

  • The predisposition hypothesis suggests that middle-aged and older adults with personality disorders are more susceptible to age-related stressors.

Explanations for Age Differences:
  • The maturation hypothesis posits that immature personality types are more likely to improve with age.

  • Age differences may be reflective of biased diagnostic criteria; selective mortality may play a role.

Assessment and Treatment:
  • Assessment measures may be biased when used with older adults.

  • Course of treatment may be slowed, complicated, and possibly impeded compared with individuals without personality disorders.

Sleep Disorders

  • Older adults who suffer from sleep difficulties are at greater risk for falling.

  • Insomnia is both an independent DSM-5 diagnosis and a diagnostic component of many other psychological and psychiatric disorders.

Etiology:
  • The predominant conceptual model of insomnia is Spielman's behavioral model.

  • Changes in sleep structure that occur with normal aging may predispose older adults to insomnia.

Assessment and Treatment:
  • Assessment of insomnia often begins with complaints of trouble falling asleep, early awakening, or daytime fatigue.

  • Effective interventions include pharmacological treatment with hypnotics and behavioral techniques.

Dementia

  • Prevalence of dementia increases with age; more common among women than men.

  • Alzheimer's disease accounts for approximately 60-70% of all dementia cases.

  • DSM-5 diagnosis is now included under the newly named major neurocognitive disorder; DSM-5 also recognizes a less severe form of cognitive impairment, mild neurocognitive disorder.

Etiology:
  • Involves the progressive deterioration of the cerebral cortex and the hippocampus.

  • Risk factors include genetic vulnerability (APOE e4 allele), beta-amyloid plaques, and tangles of a protein called tau.

Explanations for Age Differences:
  • Risk for Alzheimer's disease increases directly with advancing age.

  • Aging-related conditions may play a role via damage to the vascular system.

Assessment and Treatment:
  • Assessment involves neuropsychological testing, somatic examination, and neuroimaging.

  • There are no published interventions for primary prevention; clinicians focus on preventive treatments of cardiovascular disease.

Psycholopathology In Late Life

  • There is evidence of both similarity and difference in psychopathology in late life relative to earlier ages.

  • Contrary to popular stereotype, late life is associated with lower prevalence of many types of psychopathology.

  • Biological changes associated with aging might explain also neurocognitive disorders.

  • Assessment can be challenging.

  • Older adults who do not manifest psychopathology in spite of risk factors could be particularly helpful in uncovering protective factors.