Cardiology Diagnostic Tests

Introduction

  • The speaker expresses enthusiasm for cardiology, indicating their long-standing passion for the subject.

  • Background:

    • Graduated from the Indiana Certified College (ICC) years ago.

    • Initially hesitant to take a job on the heart floor (2 West).

    • Circumstances compelled the speaker to accept the job despite reservations.

Experience in Cardiology

  • Worked on 2 West and later with cardiologists:

    • Spent years on the Heart Floor and in the cardiac clinic.

    • There is a noted transition from being a nurse to teaching about cardiology for 20 years.

  • Encouragement for students to embrace the challenge of cardiology:

    • They will either love or hate it, which affects their performance in the field.

    • Emphasis on the complexity of the material and necessity of understanding it.

Diagnostics in Cardiology

  • Importance of Diagnostics: - The heart cannot be seen or felt directly; thus, diagnostics are essential.

  • The heart is described as a single large muscle with blood vessels, focusing on:

    • The coronary arteries:

    • Three main arteries: right coronary artery, left main coronary artery, circumflex artery (circ), left anterior descending artery (LAD).

    • These are crucial for supplying blood to the heart muscle.

Heart Attack Overview

  • Heart Attack Description:

    • Defined as a complete blockage of a coronary artery.

    • Plaque builds up, leading to platelet aggregation, and resulting in a clot.

    • When tissue supplied by the blocked artery lacks blood supply, it dies.

    • Symptoms: chest pain arises from dying muscle tissue not receiving adequate blood supply.

  • Enzymes and Biomarkers:

    • Cardiac Biomarkers: - When muscle tissue dies, it releases enzymes detectable in the blood which helps diagnose a heart attack.

      • Creatine Kinase (CK): A general indicator of muscle damage that can elevate due to exercise, injections, or heart attacks.

      • CK-MB: A cardiac-specific isoenzyme of CK used to assess damage specifically related to the heart.

      • Elevates within hours of a heart attack, peaks at approximately 24 hours, and normalizes within 12-48 hours post-event.

      • Serial measurements over 12-24 hours are necessary to monitor levels.

    • Troponin:

      • The most specific biomarker for diagnosing heart attacks.

      • Starts to elevate within hours and can remain elevated for 10 to 14 days.

      • Crucial for diagnosing delayed presentations of heart attacks (such as the hypothetical case of "Tiffany").

    • Explanation using a scenario involving Tiffany and Jamie during a heart attack:

    • Jamie presents with acute symptoms and elevated CK-MB and troponin.

    • Tiffany presents days later and may only have elevated troponin due to the delayed nature of troponin release.

Other Cardiac Biomarkers

  • C-Reactive Protein (CRP):

    • A marker for inflammation in the body indicating increased risk for heart attacks. Not typically used in the ER.

    • Used for preventive screenings to assess patient risk levels.

  • Homocysteine:

    • Another marker that indicates increased risk for coronary artery disease (CAD).

    • Like CRP, used during routine check-ups, not emergencies.

  • B-Type Natriuretic Peptide (BNP):

    • Used specifically to diagnose heart failure, with normal levels less than 100. Elevated levels indicate heart failure severity.

Lipid Profiles and Risk Factors

  • Understanding cholesterol is vital for assessing risk for coronary artery disease:

    • Total Cholesterol: Ideally less than 200 (but only a starting point).

    • Breakdown of total cholesterol into:

    • LDL (Low-Density Lipoprotein): The “bad” cholesterol which should be less than 130; for those with CAD risk factors, even lower is preferred.

    • HDL (High-Density Lipoprotein): The “good” cholesterol with a target of above 45-50.

- Triglycerides: Should be less than 160; elevated levels can indicate diabetes or alcohol intake.

  • Explanation of how high dietary intake (like fatty foods) as well as endogenous cholesterol production impacts cholesterol levels.

Serum Chemistry and Kidney Function Tests

  • Importance of Potassium Levels:

    • Essential for cardiac rhythm stability.

    • Normal levels are between 3.5-5.0 mEq/L.

    • Abnormal potassium levels (high or low) can trigger dysrhythmias and need careful monitoring during cardiac care.

  • BUN and Creatinine:

    • Used to assess kidney function which can be affected by medications given to cardiac patients.

Coagulation Studies

  • Coagulation tests are critical in determining blood health prior to procedures:

    • Activated Partial Thromboplastin Time (APTT):

    • Specific to heparin; normal range is 25-35 seconds.

    • Therapeutically higher for patients on heparin.

    • Prothrombin Time (PT):

    • Norm around 11-12.5 seconds; monitored alongside INR (2-3 for warfarin).

Electrocardiography

  • Types of EKGs:

    • 12-Leads EKG:

    • Real-time imaging, used during acute ER presentations to assess heart rhythm.

    • Holter Monitor:

    • Continuous monitoring for 24-48 hours to catch intermittent arrhythmias.

    • Event Monitor:

    • Long-term monitoring for suspected intermittent arrhythmias, can last up to 30 days.

Stress Testing

  • Purpose:

    • Assess heart response to physical stress; patients walk on a treadmill while monitored.

  • Technique:

    • Gradual increases in speed/incline to reach target heart rate.

    • EKG changes or symptoms of ischemia reveal potential blockages.

  • Beta Blocker Considerations:

    • Beta-blockers should be held before tests to allow for maximal heart rate response.

Other Imaging Techniques

  • X-rays: Used to assess structural heart changes, size, and function.

  • Echocardiography: Ultrasound imaging of cardiac structures; assesses heart function through ejection fraction.

  • CT Scans: Used to assess coronary arteries and various pathologies, often requiring beta-blockers to slow the heart down for clearer images.

Heart Catheterization

  • Procedure:

    • Diagnostic test injecting dye into heart vessels to identify blockages or issues.

  • Preparation:

    • NPO, blood tests like BUN, creatinine, INR, potassium are critical.

  • Post Care:

    • Monitoring for bleeding, assessing vital signs and pulses, especially at access sites.

Electrophysiology Testing

  • Focuses on heart rhythms; similar nursing care as cardiac catheterizations:

    • Asses vital signs, puncture sites, and rhythm stability post-procedure.

Conclusion

  • Summarize the overarching importance of diagnostics in cardiology and the student's role in mastering this information for their future practice in healthcare related to cardiology.