He says, "She should have died hereafter."
The speaker thinks he is deeply in love with his wife still.
Macbeth knows he can't win, and is desperate to find out who is going to kill him. He is already welcoming death.
He turns against God and says, "Life is a tale told by an idiot."
Life for him is now mihilistic it is a tale told by an idiot full of sound and fury signifying nothing.
When Macbeth meets Macduff, he starts to experience guilt, saying, "My soul is too much charged with blood of thine already."
This isn't arrogance saying no man can kill me, it's saying look, I've got to find this guy who's going to kill me, and I don't want to kill you in the process.
When Macduff tells him he was untimely ripped from his mother's womb, Macbeth welcomes the fear, regaining his humanity.
He is a victim of fate and victims of God. Remember he's not accepting responsibility for what he's done he is blaming the person who wrote the tale that he is acting in.