12 - equine infectious diseases and feline giardiasis

feline giardiasis

what drug is FDA-approved for the treatment of giardiasis in dogs

metronidazole

what are the top 2 drug choices for resolving the infection with this parasite in this cat? would you use both at the same time in this patient, or try just one of the m first? Why?

could use metronidazole or fenbendazole

could use both at the same time but infection can typically be resolved by using only one. the second could be added if reinfection of failure of treatment

how can the risk of neurotoxicity be minimized when treating a patient with metronidazole

careful medical math

equine adult pneumonia

what GP pathogen is a common cause of pneumonia in adult horses? What other kind of pathogens may be involved

strep zooepidemicus

enterobacterales

other streps

penicillin combined with gentamicin is a popular combination for the treatment of this condition and others in horses. Why?

penicillin covers GP and anaerobes

gentamicin covers GN and aerobes

we treat pneumonia in cattle with macrolides all the time. why don’t we do the same in horses

macrolides, lincosamides, aminoglycosides cause dysbiosis

why might nebulization of gentamicin be advantageous compared to administration by injection

direct administration to the area of infection

what does clenbuterol do, and brief MOA

bronchodilator

B2-adrenergic receptor agonists

equine neonatal sepsis

what is the specturm of activity of beta-lactams and aminoglycosides

beta-lactams

gram positive

anaerobes

aminoglycosides

aerobes

gram negative

what is am important adverse effect risk of aminoglycosides, and how can the risk be mitigated in this foal

dysbiosis

use lower doseage

why is the dosing interval of gentamicin 36 hours in foals, not 24 hours as it is in adults

foals don’t have well-developed kidneys