47, XXY (Klinefelter Syndrome)

A “normal” human being has either XX (Female) or XY (Male), however in Klinefelter syndrome you have the sex chromosome arrangement of XXY

People with 47, XXY are genetically males, most of them may no not know that they have an extra set of chromosome. 75% of XXY individuals are never diagnosed. this is one of the most common genetic conditions

There are many varied and subtle characteristics that can come from being a XXY

Physical characteristics usually occur during puberty because that when the sexual characterists begin

* There are people with 48,XXXY & 49, XXXXY but this very rare, the more the x chromosome the stronger the physical characteristics and health problems tend to be

Nondisjunction is the reason why this syndrome exists. The pair of sex chromosomes failed to separate in the egg or sperm and then fertilized with a Y.

Doctors can make a diagnosis by using a karyotype, they can also diagnised during a woman’s pregnancy.

(Karyotype: an analysis of a patient’s chromosomes take form a blood sample.

symptoms:

• testes doing fully develop

• the level of testosterone are lower

• high chance of not making sperm *Lots of males find out that they are XXY when they are looking for infertility medical help

• could be taller, longer arms and legs, less muscular bodies, more body fat, wider hips

• minor to moderate learning disabilities

• low growth of facial and body hair

• development of breast tissue and small testes

  • medical symptoms

  • osteoporosis

  • varicoses veins

  • type 2 diabetes

  • heart valve defects

  • breast cancer

• there can be mental support if need be.

This is treatable syndrome where the individual can be given hormones, and then surgery can remove the breast tissue. Although most XXY individuals are normal acting males.