MPH-102T-DRUG-DELIVERY-SYSTEM

St. James College of Pharmaceutical Sciences

Programme Details

  • College: St.James College of Pharmaceutical Sciences

  • Academy: St.James Medical Academy

  • Location: River Bank, Chalakudy

  • Course: M. Pharm - I Semester

  • Subject: Drug Delivery Systems (MPH102T)

  • Course Code: 276

  • Teaching Faculty: Dr. Smitha K Nair

Summary of Lecture Plan

Topics and Hours

  1. Sustained Release (SR) and Controlled Release (CR) Formulations - 4 Hours

  2. Polymers - 2 Hours

  3. Personalized Medicines - 2 Hours

  4. Rate Controlled Drug Delivery Systems - 2 Hours

  5. Types of Rate Controlled Drug Delivery Systems - 8 Hours

  6. Gastroretentive Drug Delivery Systems - 5 Hours

  7. Buccal Drug Delivery System - 5 Hours

  8. Ocular Drug Delivery System - 2 Hours

  9. Types of Ocular Drug Delivery Systems - 4 Hours

  10. Transdermal Drug Delivery Systems - 4 Hours

  11. Formulation and Evaluation - 6 Hours

  12. Protein and Peptide Drug Delivery - 4 Hours

  13. Formulation and Evaluation - 4 Hours

  14. Vaccine Drug Delivery - 4 Hours

  15. Mucosal and Transdermal Delivery of Vaccine - 2 Hours

Lecture Topics Breakdown

1. Sustained Release (SR) and Controlled Release (CR) Formulations

  • Introduction & Basic Concepts

  • Advantages/Disadvantages

  • Factors Influencing Formulations

  • Physicochemical & Biological Approaches

  • Mechanism of Drug Delivery from SR/CR Formulation

2. Polymers

  • Introduction, Definition, Classification

  • Applications with Examples

3. Personalized Medicine

  • Introduction, Definition

  • Categories of Patients

  • Pharmacogenetics

4. Customized Drug Delivery Systems

  • Definition, Types

5. Bioelectronic Medicines

  • Overview

6. 3D Printing of Pharmaceuticals

  • Overview

7. Telepharmacy

  • Overview

Rate Controlled Drug Delivery Systems

Overview

  • Principles & Fundamentals

  • Types of Rate Controlled Drug Delivery Systems

Modulated Drug Delivery Systems

  • Principles, Mechanism, Application

  • Mechanically Activated Systems

  • pH Activated Systems

  • Enzyme Activated Systems

  • Osmotically Activated Systems

  • Feedback Regulated Systems

Gastro-Retentive Drug Delivery Systems and Buccal Drug Delivery Systems

Gastro-Retentive Systems

  • Principle, Concepts, Advantages, and Disadvantages

  • Physiology of Stomach

  • Modulation of GI Transit Time

Buccal Delivery Systems

  • Principle of Mucoadhesion

  • Advantages and Disadvantages

  • Mechanism of Drug Permeation

  • Methods of Formulation and Evaluation

Ocular Drug Delivery Systems

Overview

  • Barriers of Drug Permeation

  • Methods to Overcome Barriers

  • Types of Ocular Drug Delivery Systems

Transdermal Drug Delivery Systems

Overview

  • Structure of Skin and Barriers

  • Penetration Enhancers

  • Different Approaches

  • Formulation and Evaluation

Protein and Peptide Drug Delivery

Overview

  • Barriers for Protein Delivery

  • Formulation of Delivery Systems

  • Evaluation of Delivery Systems

Vaccine Delivery Systems

Overview

  • Definition and Types of Vaccines

  • Uptake of Antigens

  • Single Shot Vaccines

  • Mucosal and Transdermal Delivery of Vaccines

Sample Questions

Sustained Release (SR) and Controlled Release (CR) Formulations

  1. Definition, advantages, and disadvantages of controlled drug delivery systems

  2. Factors influencing SR/CR formulation

  3. Mechanisms involved in SR/CR formulation

  4. Classification of polymers

  5. Customized drug delivery systems

  6. Telepharmacy

Rate Controlled Drug Delivery Systems

  1. Principles of rate-controlled drug delivery systems

  2. Types of rate-controlled drug delivery systems

  3. Types of osmotically activated drug delivery systems

  4. Principles of feedback regulated drug delivery systems

Gastro-Retentive Drug Delivery Systems and Buccal Drug Delivery Systems

  1. Concepts of gastroretentive drug delivery

  2. Different approaches in modulation of GI transit time

  3. Advantages and disadvantages of buccal drug delivery

  4. Principles of mucoadhesion

Ocular Drug Delivery Systems

  1. Overview of OcuSerts

  2. Types of ocular drug delivery systems

  3. Barriers of drug permeation through the eye

  4. Methods to overcome barriers

Transdermal Drug Delivery Systems

  1. Structure and physiology of skin

  2. Types of TDDS

  3. Ideal properties of drugs for TDDS formulation

  4. Examples of permeation enhancers

  5. Evaluation of TDDS

Protein and Peptide Delivery

  1. Barriers for protein drug delivery

  2. Formulation techniques for protein and peptide drugs

  3. Evaluation of protein and peptide drug delivery

Vaccine Delivery Systems

  1. Mechanism of antigen uptake

  2. Single shot vaccines

  3. Transdermal delivery of vaccines