Nutrition V

Chapter 8 Introduction


Potential energy= stored/waiting to happen


Kinetic energy= in motion


Potential in- carbs, lipids, proteins, alcohol

Turns into thermal energy/heat


1 kcal= 1000 calories


Kilojoule (kj) 1 kcal= 4.18 kj


Nutrition facts label


Chapter 8 The Atom


Atoms- fundamental unit of matter composed of protons and neutrons and electrons


Protons and neutrons- form the nucleus while electrons orbit in electron cloud


Energy and stability of atoms

-atoms are the most stable when electrons orbit in pairs

-chemical bonds form when atoms share or exchange electrons to get stability


Chemical reactions and Free radicals

  • chemical reactions- movement of electrons between atoms

  • Free radicals- (e.g. superoxide) are atoms or molecules with unpaired electrons, highly reactive and damaging to cells


Metabolism Overview:

-metabolism- encompasses all chemical reactions needed for cellular functions

-catabolism- breaking down molecules to release energy

-anabolism- building larger molecules and requires energy


Nutrient Catabolism Stages

-glycolysis- breakdown of glucose into pyruvate, yielding ATP

-citric acid cycle- acetyl-CoA, enters cycle, producing NADH, FADH2, and ATP equivalents

- electron transport chain- electron transfer generates ATP via oxidative phosphorylation


Energy Efficiency and Heat Production

-catabolism 30-40% efficient- some energy released as heat

-heat production- vital for maintaining body temperature


Anabolism and Macromolecule Synthesis

-anabolic pathways- use intermediates from catabolic processes to build macromolecules like proteins, RNA, DNA, and energy storage molecules


Regulation of Metabolic Pathways

-regulated by energy status, hormones

-excess nutrients can be stored as glycogen or fat, depending on energy needs


Clinical Relevance

-marasmus-severe malnutrition leading to muscle wasting and compromising bodily functions due to energy deficiency

-gluconeogenesis- synthesis of glucose from amino acids during fasting to maintain blood glucose levels


Storage of Energy

-excess glucose is stored as glycogen in liver and muscles

-further excess is converted to fat (lipogenesis) stored in adipocytes


Chapter 8: Weight Management


Obesogenic Environment

- environment promoting increased food intake, unhealthy foods and no activity

-2009 33% of adults 16% kids were obese


Health Consequences

-increased risks: cardiovascular disease, type 2 diabetes, certain cancers



Factors Contributing to Obesity

-fast food industry

-portion sizes- increasing since 1960’s: 1990’s trend “supersize”

-technological changes- increase in vehicles and sedentary lifestyles

-environmental influences- urbanization and less walkable cities


Combat Obesity

-individual level: whole foods, smaller portions, more activity, low calorie options

-community level: support local farms, community clean ups

-national level: support policies for walkability, campaigns against obesity, subsidies for healthy foods


Understanding Energy Balance

-calories consumed should equal calories expended to maintain body weight

-Estimated Energy Requirement(EER)- calculated based on age, sex, weight, height, physical activity level. Used to estimate daily energy needs for weight maintenance


Factors Influencing Total Energy Expenditure (TEE)

-basal metabolic rate (BMR)- energy expended at rest to maintain basic bodily functions

                 -influenced by body size, age, sex, and genetics

-thermic effect of food- 10% of TEE

-physical activity- 15-30% of TEE


Chapter 8 Factors Affecting Energy Intake


Physiological regulation of appetite

-appetite is controlled by the hypothalamus in the brain, influenced by hormonal and neural signals

-hunger and satiety are communicated through mechanical and chemical signals from the periphery

-stomach contractions and expansions send signals to the hypothalamus, influencing feelings of hunger and fullness


Role of hormones in appetite regulation

-leptin, produced by fat tissue signals satiety to the hypothalamus

-overweight people could be leptin resistant reducing it effects

-hormones from the stomach communicate fullness of hunger to the brain


Nutrients and appetite

-nutrient levels in the blood affect hunger and satiety centers in the hypothalamus

-cravings for salty and sweet foods have physiological roots linked to nutrient levels


Genetic and environmental influences

-genetics influence body fatness and weight, affecting food intake

-interaction between genetics and environment plays a role in obesity


Chapter 8 Factors Impacting Energy Expenditure


Difficulty in weight management

-set point theory

-each person has a “set point” for body fatness regulated by the brain

-changes in energy intake are triggered to maintain body fat in target range

-after dieting most people return to original weight due to “set point”

-settling point system

-considers obesogenic environments role in weight gain

-body fatness adjusts to energy intake, increased food availability or sedentary behaviors can lead to weight gain

-criticized for overgeneralizing individual responses to diet and exercise changes


Genetics and environment interaction

-prenatal nutrition can impact later in life weight and disease risk

-sedentary behavior and weight

-energy expenditure less than 1.5 times resting energy while sitting

-common in North America, contributes to reduced energy expenditure


Social factors affecting energy expenditure

-modern conveniences (elevators/cars)

-office jobs and high stress jobs limit exercise time

-modernization, urbanization, industrialization linked to rising obesity rates


Health risks

-over 25 BMI= risk of heart disease, type 2 diabetes, stroke and cancers

-increased intake of energy dense foods



Chapter 8 Recommendations for Weight Management


Healthy eating pattern that accounts for all foods and beverages within an appropriate calorie level includes: 

-fat free/low fat dairy

-oils

-variety of protein foods

-variety of fruits and whole fruits

-grains in which half are whole grains

-variety of vegetables from all subgroups


A healthy eating pattern limits

-sodium 

-added sugars

saturated/trans fats


Other recommendations to help limit:

-consume alcohol in moderation  1 drink per day for women   2 drinks for men

-consume less than 2,300 mg sodium per day

-consume less than 10% of calories per day from saturated fats

-consume less than 10% of calories from added sugars


Moderate activities

-ballroom dancing/line dancing

-biking (level ground)

-canoeing

-gardening

-baseball/softball/volleyball


Vigorous activities

-aerobic dance

-biking (more than 10 mph)

-heavy gardening (digging and hoeing)

-swimming

-fast dancing

Small amounts of aerobic activity are most beneficial


Chapter 12 Understanding Dietary Reference Intakes


Dietary Reference Intake (DRI)


Purpose: recommendation levels for certain nutrients.  An umbrella term for four reference values


Function: used as a guide for planning, assessing, and setting nutritional recommendations for the majority of the healthy population


Adequate Intake (AI)


Purpose: created for nutrients when there is insignificant consistent scientific evidence to set EAR for entire population


Function: used as a nutrient-intake goals for a given nutrient


Tolerable Upper Intake Levels (UL)


Purpose: Made to help distinguish healthful and harmful nutrients. Developed in part as a response to growing usage of dietary supplements.


Function: Indicates highest level of continuous intake of a certain nutrient that may be taken without causing health problems.