Chapter3/Exam1
Functions and Activities of the Brain
The brain is responsible for the maintenance of homeostasis within the body.
It regulates the Autonomic Nervous System () and the production and release of hormones.
It is the control center for biological drives and behavior.
It manages the cycle of sleep and wakefulness.
It regulates circadian rhythms.
It facilitates conscious mental activity.
It is responsible for memory storage and retrieval.
It enables social skills.
Cellular Composition of the Brain
Neurons: These are the primary functional units of the brain. Their roles include:
Responding to stimuli.
Conducting electrical impulses.
Releasing neurotransmitters.
Synaptic Transmission Process: The communication between neurons follows a specific pathway:
Presynaptic neuron: The neuron sending the signal.
Synapse: The junction or gap between neurons.
Postsynaptic neuron: The neuron receiving the signal.
Neurotransmitter Destruction: After a signal is transmitted, neurotransmitters must be removed to prevent overstimulation. This occurs via:
Enzymes: Chemicals that break down the neurotransmitter.
Reuptake: The process where the presynaptic neuron reabsorbs the neurotransmitter.
Organization of the Brain
Brainstem: Serves as the processing center for sensory information.
Hypothalamus: Manages basic drives and serves as a crucial link between thought and emotion and the function of internal organs.
Core: This region regulates internal organs and vital functions.
Cerebellum:
Regulates skeletal muscle activity.
Maintains equilibrium (balance).
Cerebrum: Responsible for higher-order functions including:
Mental activities.
A conscious sense of being.
Emotional status.
Memory.
Control of skeletal muscles and movement.
Language and communication.
Visualizing the Brain
Electroencephalography (): A technique used to record electrical activity of the brain.
Computed Tomography (): An imaging technique used to visualize anatomical structures.
Magnetic Resonance Imaging (): Uses magnetic fields to produce detailed images of brain structure.
Functional Magnetic Resonance Imaging (): Measures brain activity by detecting changes associated with blood flow.
Positron Emission Tomography (): An imaging test that helps reveal how tissues and organs are functioning.
Single Photon Emission Computed Tomography (): A nuclear imaging test that uses radioactive substance and a special camera to create 3D pictures to show how organs work.
Disturbances of Mental Function
Genetics: Genetic factors play a significant role in the development of mental function disturbances.
Neurotransmitters: Imbalances or issues with the following neurotransmitters are associated with mental function disturbances:
Norepinephrine
Serotonin
Dopamine
Glutamate
()
Neuropeptides
Acetylcholine
Action of Psychotropic Medications
Pharmacodynamics: This field examines what drugs do to the body and how they do it. It encompasses drug action and drug responses.
Pharmacokinetics: This field examines the movement of a drug through the body, defined by the following four processes:
Absorption
Distribution
Metabolism
Excretion
Pharmacogenetics: This field studies the effects of genetic variation on individual drug responses.
Drug Agonism and Antagonism
Agonists:
These substances mimic the effects of neurotransmitters naturally found in the human brain.
They bind to and stimulate the neurotransmitter's receptor.
Antagonists:
These substances block neurotransmitters from binding to their receptors.
They obstruct the action of the neurotransmitter.
Audience Response Questions
Question: Which neuroimaging technique would reveal problems in the anatomical structure of the brain but not problems in function?
A. CT
B. PET
C. SPECT
D. None of the above.
Answer: A. CT () is designed to reveal anatomical structure, whereas techniques like PET and SPECT are used to evaluate brain function and metabolism.