I. Differentiating Anatomy and PhysiologyAnatomy: Study of body structures, including the following types:
Gross Anatomy (Macroscopic): Examines structures that can be observed without a microscope.
Surface Anatomy: Focuses on external features of the body.
Regional Anatomy: Investigates specific body areas, such as the head or limbs.
Systemic Anatomy: Studies body systems, such as the muscular or cardiovascular system.
Developmental Anatomy: Encompasses growth and development, including embryology (study of embryos).
Microscopic Anatomy: Delves into structures not visible to the naked eye.
Histology: Examines the structure and function of tissues.
Cytology: Focuses on the analysis of cells.
Physiology: Study of body functions and processes, elaborated into:
Pathophysiology: Investigates disease processes and alterations in normal physiological functions.
Regional Physiology: Looks at the physiological function of specific body areas.
Systemic Physiology: Examines the functioning of organ systems, like the endocrine or digestive systems.
II. Homeostasis & Feedback SystemsHomeostasis: The body's ability to maintain a stable internal environment, essential for survival despite external changes.
Components:
Receptor: Detects and responds to changes in the environment, such as temperature or blood pressure.
Control Center: Analyzes information and determines the appropriate response. For example, the brain can act as a control center in temperature regulation.
Effector: Executes responses to re-establish homeostasis, like sweat glands cooling the body.
Feedback Mechanisms:
Negative Feedback: Works to oppose changes and stabilize physiological functions (e.g., body temperature regulation through vasodilation and vasoconstriction).
Positive Feedback: Encourages amplification of changes (e.g., the process of childbirth where oxytocin increases contractions).
III. Levels of OrganizationFrom the simplest to the most complex, the levels are:
Chemical Level: Consists of atoms and molecules, the fundamental building blocks of life.
Organelle Level: Includes components of cells, such as mitochondria and the nucleus.
Cellular Level: Encapsulates the basic unit of life, cells, which carry out essential functions.
Tissue Level: Groups of similar cells that perform specific functions, such as muscle or nerve tissue.
Organ Level: Structures composed of two or more tissue types functioning together, like the heart.
Organ System Level: A set of related organs working together to perform complex functions, like the digestive system.
Organismal Level: Represents the entire living entity, an individual organism.
IV. Anatomical Position & TerminologyAnatomical Position: Standardized stance for reference in anatomy studies (standing upright, facing forward, palms forward).Directional Terms: Essential for clear communication in anatomy, including:
Superior/Inferior: Indicates placement above or below.
Medial/Lateral: Refers to proximity to the midline or extremities.
Anterior/Posterior: Denotes front and back orientation.
Proximal/Distal: Refers to positions closer or farther from attachment points on limbs.Body Planes: Conceptual lines that divide the body into sections:
Sagittal Plane: Divides left and right portions.
Transverse Plane: Segments the body into upper and lower sections.
Coronal Plane: Divides the body into front and back sections.Abdominopelvic Quadrants & Regions:
Quadrants: Right Upper Quadrant (RUQ), Left Upper Quadrant (LUQ), Right Lower Quadrant (RLQ), Left Lower Quadrant (LLQ).
Regions: Epigastric, umbilical, hypogastric, along with lateral regions.
V. Body Cavities & MembranesDorsal Cavity: Encloses critical structures of the nervous system, consisting of the cranial and vertebral cavities.Ventral Cavity: Protects the internal organs, including thoracic (lungs and heart) and abdominopelvic cavities (digestive organs).Serous Membranes: Provide linings for body cavities and organs, including:
Pericardium: Surrounds the heart.
Pleura: Encloses the lungs.
Peritoneum: Lines the abdominopelvic organs.Mediastinum: The central compartment of the thoracic cavity between the lungs containing the heart and other structures.Diaphragm: A muscular structure that separates the thoracic cavity from the abdominopelvic cavity, playing a vital role in respiration.
VI. Chemical LevelBasic Terms: The foundational concepts include atoms, elements, molecules, and compounds.
4 Common Elements: Carbon (C), Hydrogen (H), Nitrogen (N), Oxygen (O) primarily compose living organisms.Atomic Structure: Consists of a nucleus (composed of protons and neutrons) and electron shells that determine chemical behavior based on atomic number, mass, and charge.Chemical Bonds:
Ionic Bonds: Formed through electron transfer between atoms.
Covalent Bonds: Established by sharing electrons; can be polar or nonpolar depending on the electronegativity of the involved atoms.
Hydrogen Bonds: Weak attractions that are important in the structure of water and biopolymers like DNA.Chemical Reactions: Various types include synthesis (combining), decomposition (breaking down), exchange (swapping components), and reversible reactions.
pH & Buffers: Acids and bases are involved in maintaining pH balance. Buffers help stabilize pH by neutralizing excess acids or bases.
VII. Organic Compounds
Carbohydrates: Categorized as monosaccharides, disaccharides, and polysaccharides serving as energy sources.
Proteins: Composed of amino acids linked by peptide bonds, crucial for numerous biological functions and structures.
Lipids: Include triacylglycerols, phospholipids, and steroids important for membrane structure and energy storage.
Nucleic Acids: Two major types:
DNA: Double-stranded structure encoding genetic information.
RNA: Single-stranded, involved in protein synthesis, consisting of purines and pyrimidines.
VIII. Cellular LevelCell Structure & Function:
Membranous Organelles: Include the nucleus, endoplasmic reticulum (ER), Golgi apparatus, and mitochondria, each playing distinct roles in cellular processes.
Non-Membranous Organelles: Comprises ribosomes (protein synthesis) and cytoskeleton (maintaining cell shape).
Plasma Membrane: A phospholipid bilayer interspersed with proteins; typical of the fluid mosaic model, it regulates transport and communication.Cell Transport:
Passive Transport: Involves movement across membranes (e.g., diffusion, osmosis, facilitated diffusion) without energy input.
Active Transport: Requires energy, such as the Na-K pump and vesicular transport mechanisms (e.g., endocytosis and exocytosis).
IX. Cell Cycle & DivisionCell Theory: Describes the fundamental properties of cells, stating that all living organisms are composed of cells and that cells arise from pre-existing cells.Cell Cycle Stages:
Interphase: Comprises G1 (cell growth), S (DNA synthesis), and G2 (preparation for mitosis).
Mitosis: Divided into phases: prophase, metaphase, anaphase, and telophase, culminating in somatic cell division.
Cytokinesis: The final process involving division of the cytoplasm to form two distinct daughter cells.Mitosis vs. Meiosis:
Mitosis: Produces two diploid somatic cells (identical to parent).
Meiosis: Results in four haploid sex cells (gametes).DNA Replication: A semiconservative process whereby each strand serves as a template to produce complementary strands.