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Unit 1: AP Bio - Chemistry of Life

Central Idea: Chemistry is the foundation of life and understanding the principles of biochemistry is essential in studying biology.

Main Branches:

  1. Atoms and Molecules

    • Subatomic particles

    • Atomic structure

    • Chemical bonds

    • Molecular formulas

  2. Water and Its Properties

    • Polarity of water

    • Hydrogen bonding

    • Cohesion and adhesion

    • High specific heat capacity

  3. Macromolecules

    • Carbohydrates

      • Monosaccharides

      • Disaccharides

      • Polysaccharides

    • Lipids

      • Fatty acids

      • Triglycerides

      • Phospholipids

      • Steroids

    • Proteins

      • Amino acids

      • Protein structure

      • Enzymes

    • Nucleic acids

      • DNA

      • RNA

  4. Chemical Reactions

    • Energy and chemical reactions

    • Enzymes and activation energy

    • Factors affecting enzyme activity

    • Metabolic pathways

  5. Cellular Respiration and Photosynthesis

    • ATP and energy transfer

    • Glycolysis

    • Krebs cycle

    • Electron transport chain

    • Photosynthesis process

  6. Acids, Bases, and pH

    • pH scale

    • Acidic, basic, and neutral solutions

    • Buffers and their role

  7. Properties of Carbon

    • Carbon bonding

    • Organic compounds

    • Functional groups

    • Isomers

  8. Biochemical Reactions

    • Dehydration synthesis

    • Hydrolysis

    • Redox reactions

    • Substrate-level phosphorylation

  9. Biological Macromolecules and Their Functions

    • Carbohydrates in energy storage and structure

    • Lipids in energy storage and cell membrane structure

    • Proteins in structure, enzymes, and cell signaling

    • Nucleic acids in genetic information storage

  10. Emergent Properties

    • Levels of biological organization

    • Emergent properties in complex systems

    • Examples of emergent properties

  11. Chemistry and the Origin of Life

    • Miller-Urey experiment

    • Prebiotic chemistry

AP Biology Unit 1: Chemistry of Life

1. Introduction to Chemistry

  • Chemistry is the study of matter and its interactions.

  • Matter is anything that occupies space and has mass.

  • Atoms are the basic units of matter, composed of protons, neutrons, and electrons.

2. Atomic Structure

  • Protons have a positive charge, neutrons have no charge, and electrons have a negative charge.

  • The atomic number represents the number of protons in an atom.

  • The mass number is the sum of protons and neutrons in an atom.

  • Isotopes are atoms with the same number of protons but different numbers of neutrons.

3. Chemical Bonds

  • Covalent bonds occur when atoms share electrons.

  • Ionic bonds form when electrons are transferred between atoms, creating ions.

  • Hydrogen bonds are weak attractions between a hydrogen atom and an electronegative atom.

4. Water and Its Properties

  • Water is a polar molecule due to its unequal sharing of electrons.

  • Cohesion is the attraction between water molecules, leading to surface tension.

  • Adhesion is the attraction between water molecules and other substances.

  • Water has a high specific heat, allowing it to resist temperature changes.

  • Water has a high heat of vaporization, making it an effective coolant.

5. pH and Buffers

  • pH measures the concentration of hydrogen ions in a solution.

  • Acidic solutions have a low pH, while basic solutions have a high pH.

  • Buffers help maintain a stable pH by accepting or donating hydrogen ions.

6. Organic Molecules

  • Carbon is the backbone of organic molecules due to its ability to form four covalent bonds.

  • Carbohydrates are composed of carbon, hydrogen, and oxygen, and serve as a source of energy.

  • Lipids are hydrophobic molecules that store energy and form cell membranes.

  • Proteins are composed of amino acids and perform various functions in cells.

  • Nucleic acids, such as DNA and RNA, store and transmit genetic information.

7. Enzymes

  • Enzymes are biological catalysts that speed up chemical reactions.

  • They lower the activation energy required for a reaction to occur.

  • Enzymes are specific to their substrates and can be regulated by factors like temperature and pH.

These notes provide a brief overview of the chemistry of life covered in AP Biology Unit 1


  1. Atom - The basic unit of matter, consisting of protons, neutrons, and electrons.

  2. Element - A pure substance made up of only one type of atom.

  3. Molecule - A group of atoms bonded together.

  4. Compound - A substance composed of two or more different elements chemically combined.

  5. Ion - An atom or molecule that has gained or lost electrons, resulting in a positive or negative charge.

  6. pH - A measure of the acidity or alkalinity of a solution.

  7. Acid - A substance that donates hydrogen ions and has a pH less than 7.

  8. Base - A substance that accepts hydrogen ions and has a pH greater than 7.

  9. Organic molecule - A molecule containing carbon atoms bonded to hydrogen atoms.

  10. Carbohydrate - A biomolecule composed of carbon, hydrogen, and oxygen, used for energy storage and structural support.

  11. Lipid - A biomolecule composed of carbon, hydrogen, and oxygen, used for energy storage, insulation, and cell membrane structure.

  12. Protein - A biomolecule composed of amino acids, used for structural support, enzymatic activity, and cell signaling.

  13. Nucleic acid - A biomolecule composed of nucleotides, used for genetic information storage and protein synthesis.

  14. Enzyme - A protein that acts as a catalyst, speeding up chemical reactions in cells.

  15. Substrate - The specific molecule that an enzyme acts upon.

  16. Active site - The region on an enzyme where the substrate binds and the chemical reaction occurs.

  17. Activation energy - The energy required to start a chemical reaction.

  18. Catalyst - A substance that speeds up the rate of a chemical reaction without being consumed in the process.

  19. Hydrolysis - A chemical reaction that breaks down molecules by adding water.

  20. Dehydration synthesis - A chemical reaction that combines molecules by removing water.

Note: This list includes key vocabulary and phrases related to the chemistry of life in AP Biology Unit 1.