vocab

metabolism - complex network of interdependent & interacting chemical reactions occurring in living organisms

  • are also the enzyme-catalysed reactions that occur in an organism, in order to convert food into energy

  • consists of anabolic & catabolic reactions

anabolism - the synthesis of complex molecules from smaller molecules

  • so meaning energy is needed in order to use small molecules, to form large molecules

    • so requires energy

  • it includes using condensation reactions to form macromolecules from monomers

catabolism - the breakdown of complex molecules into simpler molecules

  • energy is released during this process, through hydrolysis reactions

active site - composed of a few amino acids & is the region where the substrate binds & a chemical reaction occurs

substrate - reactant(s) in the metabolic reaction that bind specifically to the active site

induced fit model - a model that describes the bonding substrate with active site

  • when binding occurs, the substrate triggers a change in the enzyme’s 3D structure

    • causes enzyme to tightly hold onto the substrate

activation energy - the minimum amount of energy that is needed, in order to reach the transition state & convert the substrate into product(s)

competitive inhibition - a mechanism in which the inhibitor competes with the substrate to bind to the active site

non-competitive inhibition - a mechanism of inhibition where the inhibitor binds to an allosteric site away from the binding site

allosteric site - the location where non-competitive inhibitors bind to the enzyme

end-product inhibition/feedback inhibition - a mechanism of inhibition where the end-product acts as a non-competitive inhibitor

mechanism - based inhibition - a mechanism of inhibition where the inhibitor binds permanently to the active site

  • is irreversible