vocab
metabolism - complex network of interdependent & interacting chemical reactions occurring in living organisms
are also the enzyme-catalysed reactions that occur in an organism, in order to convert food into energy
consists of anabolic & catabolic reactions
anabolism - the synthesis of complex molecules from smaller molecules
so meaning energy is needed in order to use small molecules, to form large molecules
so requires energy
it includes using condensation reactions to form macromolecules from monomers
catabolism - the breakdown of complex molecules into simpler molecules
energy is released during this process, through hydrolysis reactions
active site - composed of a few amino acids & is the region where the substrate binds & a chemical reaction occurs
substrate - reactant(s) in the metabolic reaction that bind specifically to the active site
induced fit model - a model that describes the bonding substrate with active site
when binding occurs, the substrate triggers a change in the enzyme’s 3D structure
causes enzyme to tightly hold onto the substrate
activation energy - the minimum amount of energy that is needed, in order to reach the transition state & convert the substrate into product(s)
competitive inhibition - a mechanism in which the inhibitor competes with the substrate to bind to the active site
non-competitive inhibition - a mechanism of inhibition where the inhibitor binds to an allosteric site away from the binding site
allosteric site - the location where non-competitive inhibitors bind to the enzyme
end-product inhibition/feedback inhibition - a mechanism of inhibition where the end-product acts as a non-competitive inhibitor
mechanism - based inhibition - a mechanism of inhibition where the inhibitor binds permanently to the active site
is irreversible