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Homeostasis
Definition: Homeostasis is the body's ability to maintain stable internal conditions despite internal or external changes.
Mechanisms of Homeostasis:
Negative Feedback Mechanism:
Reverses a trend to return to a set-point.
Example: If body temperature rises, mechanisms like sweating are activated to cool the body down.
Positive Feedback Mechanism:
Amplifies or intensifies a physiologic trend until a specific goal is achieved.
Example: During childbirth, oxytocin increases contractions to deliver the baby.
Components of Negative Feedback Loop:
Stimulus: A change that disrupts homeostasis.
Receptor: Senses the change in the body (e.g., temperature sensors).
Control Center: Integrates the information from receptors (e.g., hypothalamus, medulla oblongata).
Effector: Carries out the response to return to homeostasis.
Atomic Structure
Atoms: The smallest unit of an element, made up of protons, neutrons, and electrons.
Subatomic Particles:
Protons: Positively charged, define the identity of an element; located in the atomic nucleus.
Neutrons: Neutral charge; also located in the nucleus.
Electrons: Negatively charged; orbit the nucleus and can gain/lose energy.
Atomic Mass: The sum of protons and neutrons in the nucleus.
Atomic mass reflects the element's isotopes, which possess the same number of protons but different neutrons.
Chemical Bonds
Atoms bond to achieve stable arrangements of electrons, often following the octet rule.
Types of Chemical Bonds:
Covalent Bonds: Formed when two atoms share electrons (e.g., H2O).
Single, Double, and Triple Bonds: Indicate the number of shared electron pairs.
Ionic Bonds: Formed through the transfer of electrons, resulting in charged ions (cations and anions).
Polar and Nonpolar Covalent Bonds:
Nonpolar: Electrons shared equally (e.g., O2).
Polar: Electrons shared unequally, creating a dipole (e.g., H2O).
Water Properties
Hydrophilic (water-loving) and Hydrophobic (water-fearing) molecules differ in behavior in water.
Three Crucial Properties of Water:
Polarity: Water's polar nature allows it to dissolve many substances, especially ionic and other polar molecules.
Chemical Reactivity: Participates in many chemical reactions, including hydrolysis and dehydration synthesis.
Thermal Stability: High heat capacity, which helps stabilize temperature changes and support life.
Cell Structure
Plasma Membrane: Composed of phospholipids and proteins, it regulates what enters and exits the cell.
Cytoplasm: Contains organelles and is the site of metabolic activities.
Organelles:
**Membrane-bound (e.g., nucleus, mitochondria) and Non-membrane organelles (e.g., ribosomes).
Cytoskeleton: A network of protein filaments and tubules aiding in cell shape and transport.
Intracellular vs. Extracellular Fluid:
Intracellular fluid: inside the cell; Extracellular fluid: outside the cell.
Vesicular Transport Mechanisms:
Endocytosis: Taking substances into the cell.
Exocytosis: Releasing substances from the cell.
Muscle Anatomy
Major Muscle Groups:
Quadriceps Femoris: Extends the knee; antagonist: hamstring group.
Hamstring Group: Flexes the knee; antagonist: quadriceps.
Iliopsoas: Flexes the hip; antagonist: gluteus maximus.
Gastrocnemius: Responsible for plantar flexion; antagonist: tibialis anterior.
Muscle Actions Include:
Flexion, extension, abduction, and adduction based on the anatomical position.