Female Anatomy

Anatomy

Externally

  • breasts - provide nutrition for infants

  • vulva - opening to the vagina and various functions for intercourse

Internally

  • vagina - provides entry point for sperm and ext canal for babies

  • uterus - provides home for developing embryo/fetus during pregnancy

  • ovaries - produce ova that are carried to the uterus via the uterine tubes

Breasts

  • feature a body with nipple at apex

    • nipple surrounded by areola

      • feature sensory nerve fibers that trigger the milk ejection (let-down) reflex

      • capillaries and nerves close to skin surface here

    • areolar gland secretions protect nipple from chapping/cracking during nursing

  • axillary tail (tail of spence) extends towards armpit

  • suspensory ligaments hold in place

  • non-lactating feature adipose and collagen

  • mammary glands develop in pregnancy

    • 15-20 lobes with alveoli (acini) lead to lactiferous duct → open into lactiferous sinuses → into nipple

    • glands atrophy after nursing ceases

  • myoepithelial cells are contractile cells found around ducts/acini that function in milk expression (stimulated y oxytocin)

  • breast milk is comprised of fats, carbs, proteins, vitamins, minerals, and water

  • also contain bioactive factors that augment the immature immune and digestive systems

Lactation

  • Initial stage (3-5 days postpartum) produces a nutrient-rich colostrum

  • milk “matures” after initial stage and shifts to a supply-demand system

    • breats emptying is crucial to maintaining production

      • prolactin stimulates milk production

  • let-down reflex invloves oxytocin

    • nipple nerve endings signal the hyothalamus to release oxytocin

      • milk forced from alveoli into ducts

Vulva

  • external genitalia = vulva

    • mons pubis → fat over pubic symphysis

    • labia majora and minora surround pudendal cleft

      • laia minora form the prepuce (clitoral hood)

    • pudendal cleft contains clitoris and vestibule

    • clitoris → erectile tissues that swell if aroused

      • more nerve endings than any other body part

    • vulvar vestibule → surrounds vaginal and urethral openings and contains the vestibular glands

      • lesser vestibular (skene’s/paraurethral) glands

        • secrete antimicrobial and ejaculate proteins

          • similar to prostate secretions

      • greater vestibular (bartholin’s) glands

        • secrete vaginal lubricants

  • highly variable morphology

    • variations based on amount of estrogen influence during development

      • more estrogen = larger, thicker structures

      • decrease in estrogen cn cause atrophy

  • most variation occurs within the size, shape, and color of the labia minora

    • 2018 study measured the labia of 657 participants (age range 15-84) and found:

      • average labia majora= 3.1 inches long

      • average labia minora = 1.65 inches long

      • BMI correlated with labia majora size

      • vaginal delivery correlated with labia majora length

Clitoris

  • clitoris = glans clitoris + body + crura + clitoral hood/prepuce + vestibular/clitoral bulbs

    • glans clitoris varies in size and highly innervated

      • ~8,000 nerve endings

    • prepuce protects the glans clitoris

    • body formed by the joinging of the crura

    • vestibular bulbs expand the vulva

Blood Supply

  • internal pudendal a. supplies the dorsal aa.

    • dorsal aa. gives rise to the deep dorsal aa., which supplies the corpora cavernosa that fill eith blood during erections

    • tunica albuginea

      • surrounds and separates the corpora cavernosa

      • forms the body and crura

      • helps sustain erection

  • dorsal vv. drain to the vesical plexus → internal iliac vv. → common iliac vv. → IVC

Musculature

  • various muscles act on the vulva

    • bulbospongiosus - closes the vagina and contributes to clitoral erections and orgasm contractions

    • ischiocavernosus - assists with clitoral erection

    • perinal mm. (deep transverse and superficial transverse)

      • deep transverse fixes the central tendon of the perineum (erineal body) and supports pelvic floor

    • levator ani mm. (illiococcygeus, pubococcygeus, and puborectalis)

      • supports pelvic structures, urination, childbirth, and defecation

    • sphincters (external anal and external urethral)

Internal Anatomy

  • internal organs include the ovaries, uterine tubes, uterus, and vagina

Vagina

  • located between bladder and rectum

  • 8-10 cm distensible muscular canal

    • able to expand and priduces its own lubricant

    • vaginal membrane (“hymen”) around the vaginal opening

      • typically presents as a semi-circula ring of tissue that may be a fetal remnant

        • rarely cover entire opening (imperforate hymen)

      • many myths surround this structure

  • adventitia, muscularis, and mucosa layers

    • aglandular, but lubricated by serous fluid from cervical glands and Bartholin’s glands’ secretions

  • involved on sexual pleasure, menstruation, pregnancy, and childbirth

    • walls contain many sensory nerve endings

    • allows for passage of mentrual fluid

    • allows for entry of sperm into the uterus

    • referred to as the “birth canal” during childbirth

  • acidic environment (pH 3.8-5.0) impacted by age (4.0-4.5 in reporductive years), hydration status, diet, and safe interncourse

    • pH too low = reduces fertility

    • pH too high = increased risk of infection

    • microorganisms stabilize vaginal ecosystem

      • lactobacillus acidophilus ferments glycogen from decay of vaginal mucosa into lactic acid and releases H+

Uterus

  • thick, muscular chamber that opens into the roof of the vagina and tilts forwards over the urinary bladder

  • harbors and expels a fetus

  • three main parts:

    • fundus

    • body (corpus)

    • cervix → connects to vagina

      • glands secrete cervical mucus (20-60mg/day or up to 600 mg during ovulation)

      • protects from bacteria and can prevent sperm from entering uterus

  • uterine wall made of three layers

    • perimetrium → external serosa layer

    • myometrium → middle muscular layer

      • thickest layer made mostly of smooth muscle

      • produces labor contractions

    • endometrium → inner mucosa layer

      • simple columnar epithelium

      • multiple glands and cell types

      • functional layer superficially (menstrual shed)

      • basal layer (deep) that regenerates a new functional layer each cycle

      • site of attachement during pregnancy

Uterine Tubes

  • a.k.a “oviducts” or “fallopian tubes”

  • ~10 cm long from ovary to uterus

  • muscular tube lined with ciliated cells

  • fimbriae, infundibulum, ampullam, isthumus

Ovaries

  • production of oocytes and sex hormones

    • oogenesis is the formation of oocytes

      • become ova (sing.ovum) once fertilized

    • each egg develops in a fluid-filled follicle

      • ovulation → follicle bursts and releases egg

    • follicles mature to house oocytes

      • primordial → primary → secondary → tertiary → vesticular (graafian/mature)

      • secrete estrogen, progesterone, and androgens

    • after ovulation, follicles become the corpus luteum; atrophy to corpus albicans