Introductory Chemistry (CH 1002) Test 3 Notes

Section A

Muscle Contraction

  • Myosin is involved in muscle contractions.

Protein Functionality

  • A protein is functional at the quaternary level of organization.

Defense Protein

  • Gamma-globulins are defense proteins.

Proteins in Plants

  • Fibrous proteins are not typically found in plants.

Largest Known Protein

  • Titin is the largest known protein.

Amino Acid Classification

  • Based on metabolic fate, amino acids are classified as glucogenic, ketogenic, or both.

Non-Essential Amino Acid

  • Tyrosine is not an essential amino acid.

Semi-Essential Amino Acid

  • Histidine is a semi-essential amino acid.

Amino Acid Conformation in Humans

  • Amino acids found in humans are in the L conformation.

Achiral Carbon Amino Acid

  • Glycine has an achiral carbon.

Nonapeptide and Mood

  • Oxytocin is a nonapeptide that plays a role in mood changes.

Nonpolar, Aliphatic R Groups

  • Glycine, alanine, and leucine contain nonpolar, aliphatic R groups.

Amino Acids with Negative Net Charge at pH 7.0:

  • Aspartate and glutamate have R groups with a negative net charge at pH 7.0.

Isoelectric Point Calculation

  • Given pK<em>1=2.34pK<em>1 = 2.34 and pK</em>2=9.60pK</em>2 = 9.60, the isoelectric point plpl is calculated as:
    pl=(pK<em>1+pK</em>2)/2=(2.34+9.60)/2=5.97pl = (pK<em>1 + pK</em>2) / 2 = (2.34 + 9.60) / 2 = 5.97

Peptide Bond Formation

  • During peptide bond formation, a hydroxyl group is lost from the carboxyl group of one amino acid, and a hydrogen atom is lost from the amino group of another amino acid.

Peptide Bond Type

  • A peptide bond is a covalent bond.

Tripeptide Structure

  • A tripeptide has 3 amino acids and 2 peptide bonds.

Amino Acids with Aromatic Side Chain

  • Phenylalanine, tryptophan, and tyrosine are amino acids with aromatic side chains.

Amino Acid with Zero Net Charge at Physiological pH

  • Glutamine (Gln) has a net charge of zero at physiological pH (7.0).

Protein Transport

  • Ferritin does not function as a transport molecule.

Secondary Protein Structures

  • The two common structures at the secondary level of a protein are alpha helix and beta-pleated sheets.

Secondary Level of Protein

  • The secondary level of a protein is primarily due to hydrogen bonding.

Fibrous Protein

  • Keratin is a fibrous protein.

N-Terminal Amino Acid

  • The amino acid on the N-terminal is Phenylalanine (F).

C-Terminal Amino Acid

  • The amino acid on the C-terminal is Tyrosine (Y).

Number of Peptide Bonds

  • There would be 11 peptide bonds joining the molecule together.

Molecule Type

  • This molecule is a Dodecapeptide.

Three-Letter-Abbreviation

  • The three-letter-abbreviation for the amino acid labelled I is Ile.

Amino Acid Classification

  • According to structure and chemical properties, amino acid M (Methionine) is classified as being Non-polar.

Amino Acid L

  • Amino acid L is Leucine.

Non-Aromatic Amino Acid

  • Threonine is not an aromatic amino acid.

Non-Ketogenic Amino Acid

  • Tryptophan is not a Ketogenic amino acid.

Bleomycin Type

  • Bleomycin is a Peptide anticancer drug.

Glutathione Properties

  • Glutathione is both an antioxidant and a tripeptide.

Aspartame Use

  • Aspartame is a peptide used as a food sweetener.

Enkephalins Function

  • Enkephalins are painkillers.

Peptide Hormone Regulating Muscle Tone

  • Vasopressin is a peptide hormone that plays a role in regulating the tone of muscles in blood vessels.

Non-Fibrous Protein

  • Actin is not a fibrous protein.

GABA Synthesis

  • GABA is made from Glu (Glutamate).

Serotonin Synthesis

  • Serotonin is made from Tryptophan.

Histamine Synthesis

  • Histamine is made from Histidine.

Porphyrin Synthesis

  • Porphyrins are made from Succinyl CoA and Glycine.

Largest Known Protein

  • The largest known protein is Titin.

Smallest Known Protein

  • None of the options given are correct

Solely Glucogenic Amino Acid

  • Proline is solely Glucogenic.

Number of Peptide Bonds

  • A protein with 879 amino acids would contain 878 peptide bonds.

Hemoglobin Properties

  • Hemoglobin is both a globular protein and a transport protein.

Lipoprotein Properties

  • Lipoproteins are transport proteins, used to transport lipids, and are globular proteins.

Non-Protein Function

  • Relaxation of muscles is not a function for Proteins.

Non-Amino Acid Neurotransmitter

  • None of the above are NOT neurotransmitter made from amino acids.