Study Notes on Cardiac System and Cycle

Cardiac System Overview

  • Heart Structure:

    • Specialized muscle that contracts to eject blood.

    • Located slightly left of the sternum, apex points toward left hip.

    • Apex sits at the fourth intercostal space; base at the third rib.

  • Heart Cycle:

    • Systole: Contraction of the heart; ejects blood.

    • Diastole: Relaxation of the heart; fills with blood.

  • Electrical Conduction:

    • Follows an ECG pattern identifiable by peaks (P wave, QRS complex, T wave).

    • SA Node: Initiates depolarization; spreads through atria, resulting in P wave.

    • AV Node: Delays signal; QRS complex represents ventricular depolarization.

    • T wave indicates ventricular repolarization.

  •  Mechanical Phases:

    • Diastole: Atria fill ventricles passively.

    • Atrial Contraction: Actively fills ventricles post-passive filling.

    • Isovolumetric Contraction: Ventricles contract, AV valves close (no blood ejection yet).

    • Ventricular Ejection: Blood moves out through semilunar valves; AV valves closed.

    • Isovolumetric Relaxation: Ventricles relax; semilunar valves close.

  • Heart Sounds:

    • S1 (first heart sound) heard during isovolumetric contraction.

    • S2 (second heart sound) heard during isovolumetric relaxation.

  • Electrical Events Correlation:

    • Atrial contraction starts halfway through P wave.

    • Ventricular contraction starts halfway through QRS complex.


Cardiac System Overview
  • Heart Structure:

    • Specialized cardiac muscle tissue (myocardium) that exhibits automaticity and rhythmicity, contracting involuntarily to eject blood.

      • Contains intercalated discs with gap junctions, facilitating rapid spread of electrical signals and synchronized contraction.

    • Located slightly left of the sternum in the mediastinum, within the thoracic cavity, protected by the rib cage.

    • Its apex, the pointed inferior part, points toward the left hip and rests on the diaphragm.

    • The apex typically sits at the fifth intercostal space (midclavicular line) for auscultation, while the broader base (superior aspect) is located at the level of the third rib.

    • Composed of four chambers: two atria (collecting chambers) and two ventricles (pumping chambers).

    • Contains four valves: tricuspid (right AV), mitral or bicuspid (left AV), pulmonary (right semilunar), and aortic (left semilunar), ensuring unidirectional blood flow.

  • Heart Cycle:

    • Systole: The contraction phase of the heart chambers (atrial and ventricular systole) during which blood is ejected into the arteries.

      • Ventricular systole involves a sharp increase in intraventricular pressure to overcome arterial pressure.

    • Diastole: The relaxation phase of the heart chambers (atrial and ventricular diastole) during which the heart fills with blood.

      • Ventricular diastole involves a drop in intraventricular pressure, allowing blood to flow from the atria.

  • Electrical Conduction:

    • The electrical activity of the heart follows a precise sequence, generating an ECG (Electrocardiogram) pattern identifiable by distinct peaks:

    • SA Node (Sinoatrial Node): Located in the right atrium, it is the primary pacemaker of the heart, initiating electrical impulses (depolarization) at a rate of 60-100 beats/min.

      • The impulse spreads rapidly through the atrial muscle, causing atrial contraction and resulting in the P wave on the ECG, which signifies atrial depolarization.

    • AV Node (Atrioventricular Node): Located near the interatrial septum, it receives the signal from the atria and introduces a crucial delay of approximately 0.1 seconds.

      • This delay allows for complete ventricular filling before ventricular contraction begins.

      • After the delay, the signal passes through the Bundle of His (AV bundle), bundle branches (left and right), and Purkinje fibers, rapidly spreading depolarization throughout the ventricles.

    • The QRS complex on the ECG represents ventricular depolarization, leading to ventricular contraction. Atrial repolarization also occurs during this complex but is usually masked by the larger ventricular event.

    • The T wave indicates ventricular repolarization, during which the ventricles relax and reset electrically.

  • Mechanical Phases:

    • These phases closely follow the electrical events, orchestrating blood flow:

    • Diastole (Ventricular Filling): The ventricles are relaxed; AV valves (mitral and tricuspid) are open, and semilunar valves are closed.

      • Approximately 70-80% of ventricular filling occurs passively as blood flows from the atria due to a pressure gradient.

    • Atrial Contraction (Atrial Systole): Occurs after passive filling, initiated by the SA node.

      • The atria contract, actively pushing the remaining 20-30% of blood into the ventricules. This final push is known as the "atrial kick."

    • Isovolumetric Contraction: Ventricles begin to contract, initiated by ventricular depolarization.

      • Ventricular pressure rapidly increases, exceeding atrial pressure, causing the AV valves to snap shut.

      • For a brief moment, all four heart valves are closed, so ventricular blood volume remains constant (isovolumetric) while pressure rises sharply.

    • Ventricular Ejection: When ventricular pressure exceeds the pressure in the aorta and pulmonary artery, the semilunar valves (aortic and pulmonary) are forced open.

      • Blood is then rapidly ejected from the ventricles into the great arteries. The AV valves remain closed.

    • Isovolumetric Relaxation: Ventricles begin to relax (repolarization).

      • Ventricular pressure falls rapidly below arterial pressure, causing the semilunar valves to close, preventing backflow.

      • For a brief period, all four valves are again closed, and ventricular volume remains constant (isovolumetric) as pressure continues to drop, preparing for the next filling phase.

  • Heart Sounds:

    • S1 (First Heart Sound): Often described as a "lubb" sound, it is heard during isovolumetric contraction.

      • It is caused by the sudden closure of the AV valves (mitral and tricuspid) as ventricular pressure rises, preventing backflow into the atria.

    • S2 (Second Heart Sound): Often described as a "dupp" sound, it is heard during isovolumetric relaxation.

      • It is caused by the sudden closure of the semilunar valves (aortic and pulmonary) as ventricular pressure drops below arterial pressure, preventing backflow from the great arteries.

    • Additional heart sounds, S3 and S4, can sometimes be heard, often indicating abnormalities but can be normal in some individuals (e.g., S3 in children or trained athletes).

  • Electrical Events Correlation:

    • Atrial contraction (mechanical event) begins approximately halfway through the P wave (electrical event).

    • Ventricular contraction (mechanical event) begins approximately halfway through the QRS complex (electrical event).