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ICD-10-CM 2026

Chapter 1: Certain Infectious and Parasitic Diseases

Guidelines and Examples
Overview of Coding Structure

The ICD-10-CM coding system organizes diseases and health-related conditions into chapters categorized based on the nature of the disease. Chapter 1 focuses on certain infectious and parasitic diseases. Each code corresponds to a specific condition, allowing healthcare providers to document their patient’s conditions accurately for diagnosis and treatment purposes.

Coding for Organisms Related to Infection
  1. Use of Codes B95-B97:

    • A code from category B95 (Streptococcus, Staphylococcus, and Enterococcus as the cause of diseases classified to other chapters) or B96 (Other bacterial agents) or B97 (Viral agents) must be used as an additional code to identify the organism responsible for a particular infection. This is emphasized in instructional notes accompanying infection codes.
  2. Example:

    • Acute E. coli cystitis:
      • Primary Code: N30.00
      • Additional Code: B96.20 (Unspecified Escherichia coli as the cause of diseases classified elsewhere)
      • Explanation: An instructional note under the cystitis code directs the coder to include the specific organism responsible for the infection, which in this case is E. coli.
Antibiotic Resistance and Coding
  1. Antibiotic Resistant Infections:
    • It is crucial to identify all infections documented as resistant to current antibiotics. This should be done using a code from category Z16 (Resistance to antimicrobial drugs) only if the infection code does not already specify drug resistance.
    • Example:
      • Penicillin-resistant Streptococcus pneumoniae pneumonia:
      • Primary Code: J13 (Pneumonia due to Streptococcus pneumoniae)
      • Additional Code: Z16.11 (Resistance to penicillins, which includes amoxicillin and ampicillin)
Sepsis, Severe Sepsis, and Septic Shock
  1. Coding of Sepsis and Severe Sepsis:

    • Sepsis: For a diagnosis of sepsis, assign the corresponding code for the underlying systemic infection. If unspecified, assign code A41.9 (Sepsis, unspecified organism).
    • Codes from subcategory R65.2 (Severe sepsis) should only be used if severe sepsis or acute organ dysfunction is documented.
    • Example:
      • Gram-negative sepsis: Primary Code: A41.50 (Gram-negative sepsis, unspecified)
      • Staphylococcal sepsis: Primary Code: A41.2 (Sepsis due to unspecified Staphylococcus)
    • Extreme Case:
      • Sepsis with acute organ dysfunction: If sepsis is accompanied by organ dysfunction, follow rules for severe sepsis coding, which requires both the underlying infection code and R65.2.
  2. Septic Shock:

    • Septic shock is defined as circulatory failure associated with severe sepsis, representing acute organ dysfunction. Under these conditions, the coding sequence requires the systemic infection first, followed by complication codes.
    • Example:
      • Sepsis with septic shock:
      • Primary Code: A41.9 (Sepsis, unspecified organism)
      • Follow-up Code: R65.21 (Severe sepsis with septic shock)
      • Note: Documentation of septic shock inherently implies severe sepsis, and thus it is not coded as a principal diagnosis.
Sequencing of Codes in Sepsis Diagnosis
  1. Determining Principal Diagnosis:
    • If severe sepsis is present at admission and qualifies as a principal diagnosis, the underlying systemic infection should be coded as the primary diagnosis, followed by the appropriate code from R65.2.
    • For instances where severe sepsis develops after admission, assign the underlying infection and R65.2 as secondary diagnoses. Consult the provider if documentation on the presence of severe sepsis on admission is unclear.
    • Example: If severe sepsis due to pneumonia is coded, document the pneumonia first, followed by the severe sepsis code:
      • Primary Code: A41.52 (Sepsis due to Pseudomonas)
      • Secondary Code: R65.29 (Severe sepsis without septic shock)
Postprocedural Sepsis
  1. Sepsis Following Postprocedural Infections:

    • Coding assignments for infections occurring post-procedure depend on the provider's notation of the relationship between the infection and the procedure.
    • Example: If a patient presents with a postprocedural infection leading to sepsis,
      • Primary Code: T81.41 - T81.43 (Infection following a procedure) plus appropriate sepsis codes (e.g., T81.44 for sepsis).
  2. Non-infectious Process Leading to Sepsis:

    • If sepsis or severe sepsis arises from a non-infectious process, document the non-infectious condition first, if it meets the definition of the principal diagnosis, followed by the resulting infection code.
    • Example: If a patient experiences severe sepsis due to a burn:
      • Primary Code: T20.9 (Burn of unspecified body part)
      • Secondary Code: R65.2 (Severe sepsis)
    • Only one code from category R65 should be assigned.
  3. Sepsis Associated with Pregnancy:

    • Refer to Section I.C.15 for coding of sepsis and septic shock complicating abortion, pregnancy, childbirth, and the puerperium.
  4. Newborn Sepsis:

    • For newborns, see Section I.C.16 for specific guidelines regarding bacterial sepsis with respect to age-related considerations in coding.
  5. Hemolytic-Uremic Syndrome Associated with Sepsis:

    • When hemolytic-uremic syndrome is the principal diagnosis associated with sepsis, assign code D59.31 (Infection-associated hemolytic-uremic syndrome) as the principal, with additional codes for the systemic infection and other related conditions.
Final Notes

Overall, accurate coding for infectious diseases follows a strict methodology that ensures precise documentation and treatment records. Each code serves a specific place in the diagnosis, reflecting the patient's state at the time of assessment. It is essential to understand the hierarchical nature of these codes to avoid misrepresentation of patient health conditions and ensure effective treatment pathways.