Neural Information Processing – Key Points

Neural Communication

  • Neurons transmit signals via action potentials that travel down the axon at 0.50.5130130 m/s, then cross the synapse (~1010 ms total) through neurotransmitter release.

  • Synaptic effect is either excitatory (decreases membrane potential difference → higher firing rate) or inhibitory (increases difference → lower firing rate).

Neural Representation & Computation

  • Information is encoded in firing rate (continuous quantity, up to >100100 spikes/s), not discrete 0/10/1 states.

  • Cognitive operations arise from spreading activation through excitatory and inhibitory networks.

Synaptic Plasticity & Memory

  • Activation patterns are transient; durable knowledge is stored via long-term synaptic strength changes (more transmitter release, heightened receptor sensitivity) induced by repeated use.

Distributed vs. Local Coding

  • Single-cell studies reveal feature detectors (e.g., color cones, line cells; some face-responsive neurons).

  • fMRI evidence (e.g., Haxby et al.) shows complex items (faces, objects) represented as distributed activation patterns across cortex.

Brain Organization Basics

  • Cerebral cortex (≈33 mm thick, ≈25002500 cm^2 unfolded) overlies older subcortical structures.

  • Key orientations: dorsal/superior, ventral/inferior, anterior/rostral, posterior/caudal; planes: sagittal, coronal, horizontal.

  • Lobes: frontal, parietal, temporal, occipital; major landmarks include central sulcus & Sylvian fissure.

Cortical Topography

  • Adjacent cortical neurons map adjacent sensory/motor regions (e.g., retinotopic, somatotopic maps).

  • Coarse coding: each location encoded by overlapping receptive fields → patterns across many cells.

Neuroimaging Methods (Essentials)

  • ERPs: millisecond temporal resolution from scalp potentials.

  • fMRI: detects increased oxygenated blood in active areas; high spatial but limited temporal resolution; costly & restrictive environment.

  • DTI: traces water diffusion along axons to reveal white-matter pathways.