Infection Control and Isolation

Infection Control and Isolation

Chain of Infection

  • The chain of infection is a sequence of necessary elements for an infection to occur:

    • Infectious Agent: The element that causes the infection, which can be bacteria, fungi, viruses, parasites, or prions.

    • Reservoir: The habitat where the infectious agent lives, grows, and multiplies. Examples include:

    • A stethoscope not cleaned between clients.

    • Hospital surfaces or linens and healthcare equipment.

    • Portal of Exit: The method by which the infectious agent exits the reservoir. Examples include:

    • A draining wound.

    • Vomiting.

    • Mode of Transmission: The process by which the infectious agent is transferred from the reservoir to a susceptible host. Examples include:

    • Contact Transmission: Movement of microorganisms through direct or indirect contact.

      • Direct Contact: Transfer without a contaminated object (e.g., coughing without covering mouth).

      • Indirect Contact: Transfer via contaminated objects (e.g., touching bed rails).

    • Droplet Transmission: Airborne droplets travel from an infected person's respiratory tract.

    • Airborne Transmission: Small particles in the air can infect others.

    • Portal of Entry: The route through which the infectious agent enters the susceptible host, which can be through multiple body orifices (e.g., nose, mouth, skin breaks).

    • Susceptible Host: An individual who has increased chances of infection due to weakened immune system or other factors.

Breaking the Chain of Infection

  • Hand Hygiene: The most effective way to break the chain of infection is through proper hand hygiene, both when entering and leaving a client’s room (regardless of contact).

Infectious Agents

  • Infectious agents include:

    • Bacteria

    • Fungi

    • Viruses

    • Parasites

    • Prions

  • An example includes C. Diff (Clostridium difficile) or **Staphylococcus aureus (Staph aureus)".

  • Understanding the aspects of infectious agents like their habitat and transmission is crucial.

Immunity

  • Nonspecific Immunity: Involves neutrophils and macrophages acting as phagocytes that consume and destroy microorganisms, thus providing protection.

  • Specific Immunity: Involves antibodies (immunoglobulins) that bind to infectious agents, aiding in their destruction by signaling white blood cells.

Inflammatory Response

  • Recognizes harmful stimuli via pattern receptors, activates inflammatory pathways, releases inflammatory markers, and recruits inflammatory cells.

Stages of Infection

  1. Incubation Stage: The infectious agent enters the host and multiplies.

  2. Prodromal Stage: Initial symptoms begin to manifest.

  3. Acute Illness Stage: Specific disease symptoms become pronounced and can be severe.

  4. Decline Stage: Symptoms diminish as infection is controlled.

  5. Convalescence Stage: Patient begins recovery, returning to health.

Types of Infections

  • Local Infections: Restricted to one area of the body; can be treated with topical or oral antibiotics. Symptoms include edema, redness, tenderness, and loss of function.

  • Systemic Infections: Begin as localized but spread through the bloodstream, impacting the entire body; require IV antibiotics and careful monitoring.

Hand Hygiene

  • Encompasses any cleansing method for hands, including:

    • Soap and Water: Undergoing normal hand washing procedure.

    • Alcohol-Based Hand Sanitizers: Using antiseptic hand rubs.

    • Surgical Antisepsis: Follow specific protocols in clinical settings.

  • Understand the duration needed for effective hand sanitation:

    • Handwashing: At least 20 seconds

    • Hand Sanitizers: Rubbing hands for at least 15-20 seconds

Patient Education for Infection Prevention

  • Key strategies include:

    • Vaccinations: Essential for disease prevention.

    • Cough Etiquette: Utilizing elbow to cover coughs or sneezes.

    • Nutritional Support: Good nutrition enhances immune function.

    • Control Blood Sugar Levels: Important for preventing infections.

Aseptic Techniques

  1. Medical Asepsis (Clean Technique): Aims to reduce disease-causing microorganisms.

  2. Surgical Asepsis (Sterile Technique): Eliminates or prevents transmission of infection-causing organisms.

    • Key principles include:

      • A sterile object can only remain sterile if touched by another sterile object.

      • Only sterile objects dropped from no more than 6 inches can be placed in a sterile field.

Standard Precautions

  • Infection prevention practices applied universally to all clients to avoid cross-contamination:

    • Always adhere to basic hygiene and wear appropriate personal protective equipment (PPE).

Types of Precautions Based on Client Diagnosis

  • Contact Precautions: For direct/indirect transmission involving skin or secretions.

    • Use gown and gloves.

    • Specific protocols for C. Diff (soap and water only, no alcohol gel).

  • Droplet Precautions:

    • Maintain a 3 feet distance; use surgical masks when near the patient.

    • Patient must wear a mask when leaving the room.

  • Airborne Precautions:

    • Requires a negative HEPA filtration pressure room and N95 mask that is fit tested.

  • Protective Isolation:

    • For immunocompromised patients requiring a positive HEPA filtration pressure room, with strict controls on visitor health.

Personal Protective Equipment (PPE)

  • PPE should be donned correctly before entering patient areas and removed properly to prevent self-contamination:

    • Must change PPE after each patient interaction, even without direct contact.

    • Order of PPE removal is crucial to avoid contamination.

Healthcare-Associated Infections (HAIs)

  • Major HAIs Include:

    1. Central Line Associated Bloodstream Infections (CLABSI)

    2. Catheter-Associated Urinary Tract Infections (CAUTI)

    3. Surgical Site Infections (SSI)

    4. Ventilator-Associated Pneumonia (VAP)

  • Risk Factors for infection include:

    • IV catheters.

    • Catheters or tubes.

    • Compromised immune systems due to various treatments and age considerations (elderly).

  • It is essential for nurses to use appropriate PPE and follow infection control protocols rigorously.