Hypoglycemia Protocol Notes

Hypoglycemia Screening & Management in Level I Neonates

Dextrose Gel Dosing

  • Weight-based:
    • 2000-2500g: 1 ml
    • 2502-3500g: 1.5 ml
    • 3501-4500g: 2 ml
    • 4501-5500g: 2.5 ml

Initial Management (< 72 hours, >35 weeks gestation)

  • Symptomatic/Cannot Feed:

    • Feed within 30-60 minutes of birth (breast/chest/EHM or 5ml/kg ABM).
  • CBG < 2.6 mmol/L:

    • Give dextrose gel 0.5ml/kg.
    • Feed immediately (breast/chest/EHM or 5ml/kg ABM).
    • Repeat CBG 30 minutes post-feed (within 60 minutes of previous).
  • Stable, Well, Can Feed, CBG ≥ 2.6 mmol/L:

    • Feed every 2-3 hours.
    • Check CBG pre-feed.

CBG Results & Actions

  • CBG ≥ 2.6 mmol/L:
    • Continue feeding q2-3h, check CBG AC.
    • When TWO consecutive pre-feed samples \ge 2.6 mmol/L, Repeat AC q3-6 h until 12 hours of age for LGA/IDP or until 24 hours of age for LPT/SGA
  • CBG ≥ 1.8 and < 2.6 mmol/L:
    • STAT CBG to lab.
    • Give dextrose gel 0.5ml/kg.
    • Supplement STAT with 5 ml/kg EHM or ABM.
    • Notify MRP
    • Repeat CBG 30 minutes post-feed (within 60 minutes of previous).
  • CBG < 1.8 mmol/L:
    • Admit to NICU for IV D10W.
    • Give dextrose gel 0.5ml/kg.
    • Supplement 5ml/kg EHM/ABM immediately AND then breast/chest feed.

Hypoglycemia Symptoms

  • Jitteriness/tremors, cyanotic episodes, convulsions, apnea, tachypnea, weak/high-pitched cry, hunger, lethargy/limpness/hypotonia, feeding difficulty, eye rolling.
  • Rare: sweating, pallor, hypothermia, cardiac arrest/heart failure.

Mandatory CBG Screening

  • Late preterm (LPT) < 37 weeks GA
  • Small for GA (SGA) < 10th %ile
  • Large for GA (LGA) > 90th %ile
  • Infant of diabetic parents (IDP)
  • Birth parent on Labetalol
  • Antenatal steroids for lung maturation within 5 days of birth