Organisms must respond to their environment for survival.
Stimuli include light, sound, touch, pressure, taste, temperature, and chemicals.
Advanced animals and humans have two coordination systems:
Nervous system: rapid reactions.
Endocrine system: slower reactions via hormones.
Two main divisions:
Central Nervous System (CNS): brain and spinal cord.
Peripheral Nervous System (PNS): 12 pairs of cranial nerves and 31 pairs of spinal nerves.
Receptors detect stimuli and send impulses to the CNS for processing.
Processed information is sent to effectors (nerves or glands).
Composed of millions of neurons and neuroglia (connective tissue).
Neurons: structural units of the nervous system.
Function: conduct nerve impulses.
Myelin sheath: encloses nerve fibers, formed by Schwann cells, and accelerates conduction.
Based on structure (number of extensions) and function (direction of conduction).
Types include bipolar, unipolar, and multipolar neurons.
Sensory (afferent) neurons: conduct impulses from receptors to the CNS; mostly unipolar.
Motor (efferent) neurons: conduct impulses away from the CNS to effectors; mostly multipolar.
Interneurons: connect sensory and motor neurons in the CNS; multipolar.
Axon of one neuron connects to the dendrite of another without direct contact.
The gap is called the synapse or synaptic cleft.
Synaptic vesicles contain neurotransmitters like acetylcholine or serotonin.
Neurotransmitter release is one-way, ensuring unidirectional impulse movement.
Synapses filter unimportant stimuli and prevent CNS overload.
Bone (skull and spine), cartilage, and S-shaped curvature.
Three meninges: pia mater, dura mater, and arachnoid membrane.
Cerebrospinal fluid.
Shock absorption, nutrient supply, waste removal, prevention of dehydration, and maintenance of constant pressure.
Grey matter: neuron cell bodies and dendrites.
White matter: myelinated axons.
Largest part of the brain with an outer layer called the cerebral cortex.
Functions include voluntary actions, sensations, and higher mental functions.
C-shaped structure consisting of white matter (axons) that connects the two hemispheres.
Functions: conducts impulses between hemispheres, forming a communication bridge.
Located behind and below the cerebrum; two hemispheres connected by the vermis.
Functions: coordinates voluntary actions and controls muscle tone.
Extension of the spinal cord with white matter outside and grey matter inside.
Functions: conducts nerve impulses between the spinal cord and the brain, controls autonomic functions (breathing, heart rate, etc.).
Extends from the medulla oblongata to the lumbar region.
Dorsal root: sensory neurons with a ganglion (cell body).
Ventral root: motor neurons.
Dorsal and ventral roots form the mixed spinal nerve.
Functions: provides pathways (ascending and descending tracts) and contains reflex centers.
Sensory nerves (receptors to CNS) and motor nerves (CNS to effectors).
Somatic nervous system (voluntary muscles) and autonomic nervous system (involuntary muscles).
Rapid, involuntary response to a stimulus; protective function.
Reflex centers are mainly in the spinal cord.
Natural (unconditioned) vs. learned (conditioned) reflexes.
Significance: rapid action to prevent injury and prevents overloading of the brain.
Sympathetic division: prepares the body for emergencies (fight-or-flight).
e.g., faster heart rate, higher blood pressure.
Parasympathetic division: returns the body to normal.
Two divisions are antagonistic with double innervation of target organs.
Alzheimer's Disease (AD): irreversible, progressive brain disease.
Causes: plaque accumulation, tangled nerves, neurotransmitter deficiency.
Symptoms: memory loss, confusion, and mood swings.
Treatment: manage symptoms and regulate neurotransmitters.
Multiple Sclerosis (MS): autoimmune condition affecting the brain and spinal cord.
Causes: immune system destroys myelin sheaths.
Symptoms: speech loss, inability to walk, and vision problems.
Treatment: anti-inflammatory drugs, muscle relaxants, and physical therapy.
Brain Damage
Causes: traumatic brain injury, stroke, hypoxia, cancer, and infection.
Symptoms: loss of consciousness, headaches, dizziness, and memory loss.
Spinal Damage
Causes: trauma, car accidents, violence, sports injuries, and diseases.
Symptoms: pain, loss of sensation, breathing difficulties, and muscle spasms.
- Any substance that alters normal body function by stimulating or inhibiting neurotransmitters.
- **Neurotransmitters** - Chemicals released in the synapse to conduct nerve impulses.
-Addictive drugs increase neurotransmitters and stimulate pleasure centers, creating the desire for more.
Three main types of drugs:
Stimulants: accelerate nerve impulses (e.g., caffeine, nicotine).
Depressants: slow down nerve impulses (e.g., alcohol, heroin).
Hallucinogens: cause distorted perceptions (e.g., ecstasy).
Marijuana / Dagga (Cannabis sativa)
It is commonly smoked but can be added to food or infused to drink as a tea.
Active ingredient affects brain areas related to memory, concentration, perception and movement.
Low-Medium Doses: Drowsiness, reduced coordination, excessive talkativeness, altered sense of time and space.
High Doses: Hallucinations, paranoia and panic attacks.
Heroin
Most addictive substance that mimics endorphins causing an exaggerated sense of happiness.
Side effects include vision problems, reduced concentration, decreasing libido etc.
Sharing needles can increase the odds of diseases like (HIV).
Ecstasy
Stimulant taken in social gatherings dance parties.
Side effects includes negative impact on emotions, memory, learning, anxiety, depression.
Tik / Metamfetamien
Creates a feeling of pleasure due to release of neurotransmitter dopamine.
Short term symptoms - Enlarged pupils, Assertion, Excessive sweating, Nausea Dizziness, Diarrhoea etc.
-Long term symptoms - causes insomnia, anxiety, paranoia, hallucinations, violent/aggressive behaviours and eventually death.
Respond to stimuli: light, sound, temperature, pressure, pain, and chemicals (taste and smell).
Consists of the following:
Sclera, Cornea, Choroid, Ciliary Body, Iris, Lens, Retina, Optic Nerve, Vitreous Humor
Reflex reactions adjusting to the amount of incoming light.
Bright light: pupil constricts, radial muscles relax, and circular muscles contract.
Dim light: pupil dilates, radial muscles contract, and circular muscles relax.
Far object (6m or further) Normal Eye
Suspensory ligaments exert force on the lens with less convex light is bent less.
-Near object (Closer than 6m)
Siliarily muscles contract with elastic lens becoming more convex, where light rays are refracted more.
Short-Sightedness (Myopia) - Nearby objects focus, but far objects can't be seen.
-Causes by extended eyeball abnormal curvature of the cornea, which can be corrected with concave lenses and surgery.
Long-Sightedness (Hyperopia) - Distant objects are clearly seen.
-Causes by a shorter eyeball with abnormal flat cornea, which can be corrected with convex lenses and surgery.
Astigmatism - Hazy image due to cornea/lens having an irregular shape,which can be treated with medical procedures.
Cataracts - lens starts getting dense thus not letting enough light passing through, treated with medical procedures.
Responds to sound stimuli and detects head movements to help maintain balance/equilibrium.
Human Ear is divided into three parts - External Ear, Middle Ear, and Internal Ear.
Pinna - Captures Sound waves to audience opening
External Auditory Canal - conducts sound waves
Tympanic Membrane - converts sound waves into vibrations
Middle Ear bones - hammer (Malleus), anvil (Incus) and stapes (Stapes)
-Oval window - Transmits vibrations from air filled middle ear cavity.
Round window - pressure waves in the perilymph are absorbed
Eustachian tube - Connects the Middle ear to the pharynx
Vestibular Apparatus - Balance
Cochlea - Hearing
Maculae - provides position related info
Cristae (in Ampulla of semicircular canals) - observes changes
Amplification due toLever system formed by decrease in size of the ossicles
Larger tympanic membrane transmitting vibrations to the smaller oval window
Conductive deafness - Transferring vibrations to internal part,can be temporary/permanent which could need surgery.
Nerve Deafness - Due to sensory hair-cells getting damaged leading to auditory nerves which can be permanent with/without Cochler implants.